Methods to Screen Compounds Against Mutant p53 Misfolding and Aggregation for Cancer Therapeutics

2018 ◽  
pp. 265-277
Author(s):  
Giulia Diniz da Silva Ferretti ◽  
Danielly C. Ferraz da Costa ◽  
Jerson L. Silva ◽  
Luciana Pereira Rangel
Keyword(s):  
Cancer Therapeutics ◽  
Mutant P53

scholarly journals Zinc Metallochaperones Reactivate Mutant p53 Using an ON/OFF Switch Mechanism: A New Paradigm in Cancer Therapeutics

2018 ◽  
Vol 24 (18) ◽  
pp. 4505-4517 ◽  
Author(s):  
Xin Yu ◽  
Samuel Kogan ◽  
Ying Chen ◽  
Ashley T. Tsang ◽  
Tracy Withers ◽  
...  
Keyword(s):  
Cancer Therapeutics ◽  
Mutant P53 ◽  
New Paradigm ◽  
Switch Mechanism

scholarly journals Zinc Metallochaperones as Mutant p53 Reactivators: A New Paradigm in Cancer Therapeutics

Cancers ◽  
2018 ◽  
Vol 10 (6) ◽  
pp. 166 ◽  
Author(s):  
Samuel Kogan ◽  
Darren Carpizo
Keyword(s):  
Cancer Therapeutics ◽  
Mutant P53 ◽  
New Paradigm

Abstract 3432: Zinc metallochaperones for mutant p53 reactivation in cancer therapeutics

2020 ◽  
Author(s):  
Xin Yu ◽  
Bing Na ◽  
Saif Zaman ◽  
Tracy Withers ◽  
John Gilleran ◽  
...  
Keyword(s):  
Cancer Therapeutics ◽  
Mutant P53 ◽  
P53 Reactivation

Mutant p53 inhibits helicobacter-induced premalignant lesions through downregulation of Th1 proinflammatory responses

2001 ◽  
Vol 120 (5) ◽  
pp. A87-A87
Author(s):  
J FOX ◽  
B SHEPPARD ◽  
C DANGLER ◽  
M WHARY ◽  
M IHRIG ◽  
...  
Keyword(s):  
Premalignant Lesions ◽  
Mutant P53 ◽  
Proinflammatory Responses

In Search of Novel Cancer Therapeutics: Assessing the NCI Natural Product Library against Ten Anti-Apoptotic Protein Targets

Planta Medica ◽  
2013 ◽  
Vol 79 (10) ◽  
Author(s):  
DB Divlianska ◽  
AE Wright ◽  
S Francis ◽  
MA Walters ◽  
CE Salomon ◽  
...  
Keyword(s):  
Natural Product ◽  
Cancer Therapeutics ◽  
Protein Targets ◽  
Apoptotic Protein ◽  
Natural Product Library

Src Kinase Inhibitors: Promising Cancer Therapeutics?

2012 ◽  
Vol 17 (2) ◽  
pp. 145-159 ◽  
Author(s):  
Helen Creedon ◽  
Valerie G . Brunton
Keyword(s):  
Kinase Inhibitors ◽  
Src Kinase ◽  
Cancer Therapeutics
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