Thrombolytic Therapy for Acute Myocardial Infarction With ST-Segment Elevation

1999 ◽  
pp. 201-241 ◽  
Author(s):  
Jeffrey L. Anderson ◽  
Sanjeev Trehan
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Thrombolytic Therapy ◽  
St Segment Elevation ◽  
St Segment

Resolution of ST-segment elevation in acute myocardial infarction — Early prognostic significance after thrombolytic therapy

Herz ◽  
1999 ◽  
Vol 24 (6) ◽  
pp. 440-447 ◽  
Author(s):  
Joerg Carlsson ◽  
Uwe Kamp ◽  
Dirk Härtel ◽  
Johannes Brockmeier ◽  
Rainer Meierhenrich ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Thrombolytic Therapy ◽  
Prognostic Significance ◽  
St Segment Elevation ◽  
St Segment

scholarly journals Early ST-segment elevation acute myocardial infarction after thrombolytic therapy for acute ischemic stroke

Medicine ◽  
2018 ◽  
Vol 97 (50) ◽  
pp. e13347 ◽  
Author(s):  
Maria Mirabela Manea ◽  
Dorin Dragoş ◽  
Emanuel Stoica ◽  
Adrian Bucşa ◽  
Ioana Marinică ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Ischemic Stroke ◽  
Thrombolytic Therapy ◽  
Acute Ischemic Stroke ◽  
St Segment Elevation ◽  
St Segment ◽  
Elevation Acute Myocardial Infarction

scholarly journals Что мы знаем сегодня об отечественном тромболитическом препарате рекомбинантная проурокиназа (пуролаза)

2019 ◽  
Author(s):  
S.G. Milenkina ◽  
E.P. Delver ◽  
A.A. Belogurov ◽  
R.SH. Bibilashvilli ◽  
E.V. Arzamastsev ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Thrombolytic Therapy ◽  
Coronary Intervention ◽  
Technical Aspects ◽  
St Segment Elevation ◽  
Thrombolytic Drug ◽  
St Segment ◽  
Percutaneous Coronary ◽  
Current Guidelines

В обзоре представлены основные данные о создании отечественного тромболитического препарата III поколения рекомбинантной проурокиназы и применении ее у пациентов с острым инфарктом миокарда с подъемом сегмента ST (ИМпST). Современные рекомендации отдают предпочтение первичному чрескожному коронарному вмешательству (ЧКВ). Однако ряд логистических и технических особенностей нередко делает проведение ЧКВ в рекомендованные сроки невозможным, и медикаментозная реперфузия остается методом выбора. Своевременная тромболитическая терапия (ТЛТ) позволяет уменьшить время до начала реперфузии и улучшить прогноз больного. Накоплен значительный опыт догоспитального и госпитального применения рекомбинантной проурокиназы. В статье рассмотрены результаты основных исследований эффективности и безопасности, а также особенностей применения рекомбинантной проурокиназы, в том числе при использовании фармакоинвазивного подхода к лечению ИМпST. Ключевые слова: острый инфаркт миокарда с подъемом сегмента ST, тромболитическая терапия, пуролаза, рекомбинантная проурокиназа, фармакоинвазивный подход.The review presents the main data on the development of thrombolytic drug of the III generation of recombinant prourokinase produced in Russia and its administration in patients with acute myocardial infarction with ST segment elevation (STEMI). Current guidelines prefer primary percutaneous coronary intervention (PCI). However, a number of logistical and technical aspects often make it impossible to carry out PCI within the recommended time, and drug reperfusion remains the method of choice. Well-timed thrombolytic therapy (TLT) can reduce the time before reperfusion and improve the patients prognosis. Significant experience in pre-hospital and hospital is adepted at use of recombinant prourokinase. The article considers the results of the main studies of the effectiveness and safety, as well as the aspects of the use of recombinant prourokinase, including the use of pharmacoinvasive approach to the treatment of STEMI. Key words: acute myocardial infarction with ST-segment elevation, thrombolytic therapy, Purolase, pharmacoinvasive approach.

ST Elevation is not Always Equivalent to Acute Myocardial Infarction: a Case of Brugada Syndrome

2003 ◽  
Vol 10 (2) ◽  
pp. 121-123
Author(s):  
YF Choi ◽  
AYC Siu ◽  
TW Wong ◽  
CC Lau
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Emergency Department ◽  
Thrombolytic Therapy ◽  
Brugada Syndrome ◽  
Diagnostic Tools ◽  
St Segment Elevation ◽  
St Segment ◽  
St Elevation ◽  
Electrocardiogram Ecg

Acute myocardial infarction (AMI) is one of the most alerting situations in emergency department. Electrocardiogram (ECG) is one of the most important diagnostic tools and the decision about thrombolytic therapy is usually based upon ECG findings when clinically suspicious. However, ST segment elevation is not always equivalent to acute myocardial infarction. We present a rare syndrome whose ECG shows persistent ST elevation not related to AMI.

scholarly journals Cerebral Infarction Caused by Thrombolytic Therapy for Acute Myocardial Infarction a Case Report and Literature Review

2020 ◽  
Vol 4 (4) ◽  
pp. 01-04
Author(s):  
Wei Liu
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Case Report ◽  
Cerebral Infarction ◽  
Thrombolytic Therapy ◽  
Common Complication ◽  
St Segment Elevation ◽  
Segment Elevation Myocardial Infarction ◽  
St Segment ◽  
The Common

Background: Thrombolytic therapy is one of the effective treatments for ST-segment elevation myocardial infarction. The most common complication of thrombolytic therapy is hemorrhage. Thromboembolism caused by thrombolytic therapy is exceedingly rare in clinical practice. However, we report a case of cerebral infarction caused by thrombolytic therapy for acute myocardial infarction. Case Report: A 70-year-old man complained of burning sensation under the xiphoid process for 7 years and sudden chest pain for 3 hours. He was diagnosed with acute anterior ST-segment elevation myocardial infarction. Thrombolytic therapy was carried out immediately, but the patient developed cerebral infarction 3 hours after thrombolysis. CONCLUSION: The common complication of thrombolytic therapy is cerebral hemorrhage or gastrointestinal hemorrhage, but the possibility of cerebral infarction should also be taken into account when patients have neurological symptoms.

scholarly journals Application Effect of Intelligent Monitoring of Emergency Nursing Process Reengineering in the Thrombolytic Therapy of Acute Myocardial Infarction

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Xueqing Liu ◽  
Sufang Huang ◽  
Jing Cheng ◽  
Ying Zhang
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Thrombolytic Therapy ◽  
First Aid ◽  
Emergency Nursing ◽  
Nursing Process ◽  
St Segment Elevation ◽  
Segment Elevation Myocardial Infarction ◽  
St Segment ◽  
Flow Group

The application of emergency nursing process in intravenous thrombolytic therapy for patients with acute myocardial infarction was discussed. 100 patients with ST segment elevation myocardial infarction who met the inclusion and exclusion criteria were selected for intravenous thrombolysis. 50 patients with ST segment elevation myocardial infarction were treated from December 2018 to June 2019. The first-aid time and treatment effect of the two groups were compared. The results showed that the first aid time in the optimized process group was less than that in the conventional flow group ( P < 0.05 ); the ECG rate was higher within 10 min than that in the conventional flow group ( P < 0.05 ). It indicates that standardized and meticulous nursing procedures can avoid repetition and omissions and improve work efficiency. The application of the emergency care process in the emergency care of patients with acute myocardial infarction can win more rescue time and then improve the success rate of their rescue.

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