Genetic Mouse Models of Psychiatric Disorders

2007 ◽  
pp. 177-191
Author(s):  
Joseph A. Gogos ◽  
Maria Karayiorgou
Keyword(s):  
Psychiatric Disorders ◽  
Mouse Models ◽  
Genetic Mouse Models

Behavioral phenotyping of Nestin-Cre mice: Implications for genetic mouse models of psychiatric disorders

2014 ◽  
Vol 55 ◽  
pp. 87-95 ◽  
Author(s):  
Sebastian A. Giusti ◽  
Claudia A. Vercelli ◽  
Annette M. Vogl ◽  
Adam W. Kolarz ◽  
Natalia S. Pino ◽  
...  
Keyword(s):  
Psychiatric Disorders ◽  
Mouse Models ◽  
Behavioral Phenotyping ◽  
Genetic Mouse Models

The function of NO-sensitive guanylyl cyclase: What we can learn from genetic mouse models

Nitric Oxide ◽  
2009 ◽  
Vol 21 (3-4) ◽  
pp. 149-156 ◽  
Author(s):  
Andreas Friebe ◽  
Doris Koesling
Keyword(s):  
Mouse Models ◽  
Guanylyl Cyclase ◽  
Genetic Mouse Models

scholarly journals Association of Nrf2 with airway pathogenesis: lessons learned from genetic mouse models

2015 ◽  
Vol 89 (11) ◽  
pp. 1931-1957 ◽  
Author(s):  
Hye-Youn Cho ◽  
Steven R. Kleeberger
Keyword(s):  
Mouse Models ◽  
Lessons Learned ◽  
Genetic Mouse Models

scholarly journals Characterization of spatio-temporal epidural event-related potentials for mouse models of psychiatric disorders

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Xin Wang ◽  
António Pinto-Duarte ◽  
M. Margarita Behrens ◽  
Xianjin Zhou ◽  
Terrence J. Sejnowski
Keyword(s):  
Psychiatric Disorders ◽  
Mouse Models ◽  
Event Related Potentials ◽  
Related Potentials ◽  
Spatio Temporal

Functional genetic mouse models: promising tools for investigation of the proteolytic internet

2009 ◽  
Vol 390 (2) ◽  
pp. 91-97 ◽  
Author(s):  
Achim Krüger
Keyword(s):  
Mouse Models ◽  
Knockout Mice ◽  
Gold Standard ◽  
Disease Susceptibility ◽  
Molecular Polymorphism ◽  
Specific Protease ◽  
Molecular Phenotypes ◽  
The Impact ◽  
Genetic Mouse Models

Abstract Knockout mice are the gold standard to probe for the role of a specific protease within the interacting network of proteases, substrates, and inhibitors. This proteolytic network, or protease web, determines cell signaling and organ homeostasis. Therefore, protease deficiency or inhibition is intrinsically tied to alterations within this network, always leading to new molecular phenotypes, which define susceptibility of an organ to disease. Furthermore, recent hints, mainly from research on matrix metalloproteinases, about the impact of the protease web on inter-organ signaling molecules suggest the existence of a proteolytic internet of communicating local organ- or molecular polymorphism-specific networks, thereby defining homeostasis and disease susceptibility in the whole organism.

Behavioral phenotypes and pharmacology in genetic mouse models of Parkinsonism

2006 ◽  
Vol 17 (5-6) ◽  
pp. 383-391 ◽  
Author(s):  
Sheila M. Fleming ◽  
Marie-Fran??oise Chesselet
Keyword(s):  
Mouse Models ◽  
Behavioral Phenotypes ◽  
Genetic Mouse Models
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