Functional Analysis of Human D1 and D5 Dopaminergic G Protein-Coupled Receptors: Lessons from Mutagenesis of a Conserved Serine Residue in the Cytosolic End of Transmembrane Region 6

2012 ◽  
pp. 141-180 ◽  
Author(s):  
Bianca Plouffe ◽  
Mario Tiberi
Keyword(s):  
Functional Analysis ◽  
G Protein ◽  
G Protein Coupled Receptors ◽  
Serine Residue ◽  
Transmembrane Region ◽  
G Protein Coupled

scholarly journals GPCRtm: An amino acid substitution matrix for the transmembrane region of class A G Protein-Coupled Receptors

2015 ◽  
Vol 16 (1) ◽  
Author(s):  
Santiago Rios ◽  
Marta F. Fernandez ◽  
Gianluigi Caltabiano ◽  
Mercedes Campillo ◽  
Leonardo Pardo ◽  
...  
Keyword(s):  
Amino Acid ◽  
G Protein ◽  
Amino Acid Substitution ◽  
G Protein Coupled Receptors ◽  
Substitution Matrix ◽  
Transmembrane Region ◽  
Class A ◽  
Amino Acid Substitution Matrix ◽  
G Protein Coupled

An atlas and functional analysis of G-protein coupled receptors in human islets of Langerhans

2013 ◽  
Vol 139 (3) ◽  
pp. 359-391 ◽  
Author(s):  
Stefan Amisten ◽  
Albert Salehi ◽  
Patrik Rorsman ◽  
Peter M. Jones ◽  
Shanta J. Persaud
Keyword(s):  
Functional Analysis ◽  
G Protein ◽  
Islets Of Langerhans ◽  
Human Islets ◽  
G Protein Coupled Receptors ◽  
Human Islets Of Langerhans ◽  
G Protein Coupled

A cholesterol consensus motif is required for efficient intracellular transport and raft association of a group 2 HA from influenza virus

2015 ◽  
Vol 465 (2) ◽  
pp. 305-314 ◽  
Author(s):  
Maren de Vries ◽  
Andreas Herrmann ◽  
Michael Veit
Keyword(s):  
Influenza Virus ◽  
G Protein ◽  
Intracellular Transport ◽  
G Protein Coupled Receptors ◽  
Transmembrane Region ◽  
Consensus Motif ◽  
Group 2 ◽  
External Part ◽  
G Protein Coupled

The external part of the transmembrane region of HA (haemagglutinin) of influenza virus contains a cholesterol consensus motif originally identified in G-protein-coupled receptors. Various mutations in this motif retard transport of HA through the Golgi and reduce raft association.

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