Molecularly Imprinted Polymers: Promising Advanced Materials for In Vivo Sensing

Author(s):  
Yi Ge ◽  
Samir Akhtar ◽  
Farhan Mirza ◽  
Sergey Piletsky ◽  
Shenqi Wang ◽  
...  
BioTechniques ◽  
2020 ◽  
Vol 69 (6) ◽  
pp. 406-419
Author(s):  
Zahra El-Schich ◽  
Yuecheng Zhang ◽  
Marek Feith ◽  
Sarah Beyer ◽  
Louise Sternbæk ◽  
...  

Molecularly imprinted polymers (MIPs) are currently widely used and further developed for biological applications. The MIP synthesis procedure is a key process, and a wide variety of protocols exist. The templates that are used for imprinting vary from the smallest glycosylated glycan structures or even amino acids to whole proteins or bacteria. The low cost, quick preparation, stability and reproducibility have been highlighted as advantages of MIPs. The biological applications utilizing MIPs discussed here include enzyme-linked assays, sensors, in vivo applications, drug delivery, cancer diagnostics and more. Indeed, there are numerous examples of how MIPs can be used as recognition elements similar to natural antibodies.


Nano Letters ◽  
2017 ◽  
Vol 17 (4) ◽  
pp. 2307-2312 ◽  
Author(s):  
Alessandra Cecchini ◽  
Vittoria Raffa ◽  
Francesco Canfarotta ◽  
Giovanni Signore ◽  
Sergey Piletsky ◽  
...  

Author(s):  
Maylis Garnier ◽  
Michele Sabbah ◽  
Christine Ménager ◽  
Nébéwia Griffete

Molecularly imprinted polymers (MIPs) have been widely used in nanomedicine during the last few years. However, their potential is limited by their intrinsic properties resulting, for instance, in lack of control in drug release processes or complex detection for in vivo imaging. Recent attempts in creating hybrid nanomaterials combining MIPs with inorganic nanomaterials succeeded in providing a wide range of new interesting properties suitable for nanomedicine. Through this review, we aim to illustrate how hybrids molecularly imprinted polymers may improve patient care with enhanced imaging, treatments and combination of both.


Talanta ◽  
2020 ◽  
Vol 219 ◽  
pp. 121283
Author(s):  
Jia-Wei Zhang ◽  
Jia-Yuan He ◽  
Chong-Zhi Wang ◽  
Feng-Qing Yang ◽  
Lian-Di Zhou ◽  
...  

Nanomaterials ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 3091
Author(s):  
Maylis Garnier ◽  
Michèle Sabbah ◽  
Christine Ménager ◽  
Nébéwia Griffete

Molecularly imprinted polymers (MIPs) have been widely used in nanomedicine in the last few years. However, their potential is limited by their intrinsic properties resulting, for instance, in lack of control in drug release processes or complex detection for in vivo imaging. Recent attempts in creating hybrid nanomaterials combining MIPs with inorganic nanomaterials succeeded in providing a wide range of new interesting properties suitable for nanomedicine. Through this review, we aim to illustrate how hybrid molecularly imprinted polymers may improve patient care with enhanced imaging, treatments, and a combination of both.


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