Postoperative Adjuvant Therapy for Completely Resected Esophageal Cancer

2007 ◽  
pp. 265-270
Author(s):  
Nobutoshi Ando
Keyword(s):  
Esophageal Cancer ◽  
Adjuvant Therapy ◽  
Postoperative Adjuvant Therapy

Analysis of new N descriptors on prognosis of esophageal cancer with positive lymph nodes in a Chinese population.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e14678-e14678
Author(s):  
Yaping Xu
Keyword(s):  
Decision Making ◽  
Esophageal Cancer ◽  
Adjuvant Therapy ◽  
Lymph Nodes ◽  
Staging System ◽  
Postoperative Adjuvant Therapy ◽  
Cox Regression Analysis ◽  
Significant Difference ◽  
N Staging ◽  
Positive Lymph Nodes

e14678 Background: The 7th edition of the American Joint Committee on Cancer / Union International Against Cancer (AJCC/UICC) TNM staining system for esophageal cancer (EC) has been published. N descriptors are now divided into N0, N1, N2 and N3. In this study, we aimed to validate the prognostic ability of the new N staging system in patients with resectable EC and positive lymph nodes, and evaluate whether the new N staging system can help the decision-making for postoperative adjuvant therapy in this population. Methods: From 2002 to 2008, patients with stage T1-4N1-3M0 EC who underwent esophagectomy were retrospectively analyzed. EC was classified according to the new N staging system. Kaplan-Meier method and Cox regression analysis were employed to compare overall survival (OS). Results: A total of545 patients met the inclusion criteria: 346 (63.5%) received esophagectomy alone, 199 (36.5%) received esophagectomy and adjuvant radiotherapy, and 36.1% (197/545) received esophagectomy and adjuvant chemotherapy. Univariate analysis and multivariate analysis revealed significant difference in OS among patients with EC at different N stages (p<0.001). Significant difference in OS was also present among patients receiving radiotherapy (p<0.001) and those undergoing chemotherapy (p<0.001). Subgroup analysis indicated that postoperative adjuvant therapy did not significantly affect the OS among patients with EC at different N stages. Conclusions: Our results validated the prognostic ability of new N staging system. N descriptor is an independent prognostic factor in patients with resectable EC who were positive for lymph nodes. Further studies are required to clarify the role of new N staging system in the decision-making for postoperative adjuvant therapy in this population.

scholarly journals PO-0685: The value of postoperative adjuvant therapy for pT2-3 esophageal cancer treated by radical resection

2017 ◽  
Vol 123 ◽  
pp. S358
Author(s):  
S. Zhu ◽  
L. Shuguang ◽  
L. Youmei ◽  
S. Wenbin ◽  
L. Juan ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Adjuvant Therapy ◽  
Radical Resection ◽  
Postoperative Adjuvant Therapy

scholarly journals Nutritional support for the patients with esophageal cancer during the postoperative adjuvant therapy.

1988 ◽  
Vol 21 (7) ◽  
pp. 1919-1923
Author(s):  
Yorikazu NIITSU ◽  
Kaoru ISHIDA ◽  
Kazumi OKAMOTO ◽  
Shunsuke SUZUKI ◽  
Kouji MURAKAMI ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Adjuvant Therapy ◽  
Nutritional Support ◽  
Postoperative Adjuvant Therapy

scholarly journals Postoperative adjuvant therapy for resectable esophageal cancer

Medicine ◽  
2019 ◽  
Vol 98 (20) ◽  
pp. e15485 ◽  
Author(s):  
Tianci Chai ◽  
Zhimin Shen ◽  
Peipei Zhang ◽  
Yuhan Lin ◽  
Sui Chen ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Adjuvant Therapy ◽  
Postoperative Adjuvant Therapy ◽  
Resectable Esophageal ◽  
Resectable Esophageal Cancer
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