Technologies, for memory preservation and enhancement of our humane bodies, are developing at a fast pace, and the corresponding dystopic and utopic future scenarios are presented in speculative news reports, science research studies and popular culture such as science fiction films. Lopes' artistic/research projects explore ways of expanding concepts of memory, body, and representation/mediation, using art as a tool to enhance public awareness of several anxieties and technologies, raising ethical dilemmas and questioning norms of behavior and normality. This chapter is an exploration of the issues raised on the development of several artwork projects during the course of the author's PhD and present Postdoc research, when in residency at several Medical and Scientific Research Institutes, dealing with distinct studies on memory (functioning, loss and enhancement).