scholarly journals Procedural Modelling as a Tool for Morphological Analysis of the Design Idea

2019 ◽  
pp. 243-253
Author(s):  
Jessica Romor
Keyword(s):  
Morphological Analysis ◽  
Design Idea

Structural and Chemical Studies of Pathological Fibers in Human Neurofibrillary Degeneration

1985 ◽  
Vol 43 ◽  
pp. 726-729
Author(s):  
K.S. Kosik ◽  
L.K. Duffy ◽  
S. Bakalis ◽  
C. Abraham ◽  
D.J. Selkoe
Keyword(s):  
Monoclonal Antibodies ◽  
Alzheimer Disease ◽  
Human Brain ◽  
Neurofibrillary Tangles ◽  
Morphological Analysis ◽  
High Specificity ◽  
Cytoskeletal Proteins ◽  
Neuritic Plaque ◽  
Protein Chemistry ◽  
Chemical Studies

The major structural lesions of the human brain during aging and in Alzheimer disease (AD) are the neurofibrillary tangles (NFT) and the senile (neuritic) plaque. Although these fibrous alterations have been recognized by light microscopists for almost a century, detailed biochemical and morphological analysis of the lesions has been undertaken only recently. Because the intraneuronal deposits in the NFT and the plaque neurites and the extraneuronal amyloid cores of the plaques have a filamentous ultrastructure, the neuronal cytoskeleton has played a prominent role in most pathogenetic hypotheses.The approach of our laboratory toward elucidating the origin of plaques and tangles in AD has been two-fold: the use of analytical protein chemistry to purify and then characterize the pathological fibers comprising the tangles and plaques, and the use of certain monoclonal antibodies to neuronal cytoskeletal proteins that, despite high specificity, cross-react with NFT and thus implicate epitopes of these proteins as constituents of the tangles.

Design idea of 'ultra hypotoxic multidrug' based on the “efficacy theory” of traditional Chinese medicines

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
SQ Cai ◽  
X Feng ◽  
MY Shang ◽  
X Wang
Keyword(s):  
Traditional Chinese Medicines ◽  
Chinese Medicines ◽  
Design Idea

Morphological analysis of selective destruction of pancreatic beta-cells by cytotoxic T lymphocytes in NOD mice

Diabetes ◽  
1991 ◽  
Vol 40 (9) ◽  
pp. 1210-1217 ◽  
Author(s):  
M. Hayakawa ◽  
K. Yokono ◽  
M. Nagata ◽  
N. Hatamori ◽  
W. Ogawa ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
Beta Cells ◽  
Cytotoxic T Lymphocytes ◽  
Pancreatic Beta Cells ◽  
Morphological Analysis ◽  
Nod Mice ◽  
Selective Destruction

Systemic mastocytosis: clinical and morphological analysis five patients with a rare disease

2019 ◽  
Vol XIV (2) ◽  
Author(s):  
I.L. Plaksa ◽  
S.S. Savin ◽  
E.M. Charlanova ◽  
V.M. Kravcova ◽  
B.V. Afanasiev
Keyword(s):  
Rare Disease ◽  
Morphological Analysis ◽  
Systemic Mastocytosis

Taxonomic Revision of Chionoloma (Pottiaceae, Bryophyta)

2019 ◽  
Vol 104 (4) ◽  
pp. 563-632 ◽  
Author(s):  
Marta Alonso ◽  
Juan A. Jiménez ◽  
María J. Cano
Keyword(s):  
Morphological Analysis ◽  
New Records ◽  
Taxonomic Revision ◽  
Field Trips ◽  
Distribution Data

A worldwide taxonomic revision of the species belonging to the moss genus Chionoloma Dixon (Pottiaceae) is here presented. Our work is based on the morphological analysis of more than 2600 specimens deposited in different herbaria or collected during field trips. A total of 131 names were found and their nomenclatural types were examined, resulting in the lectotypification of 45 names. It is concluded that Chionoloma is composed of 22 species and one variety, seven of them are here newly combined (C. circinatum (Besch.) M. Alonso, M. J. Cano & J. A. Jiménez; C. cylindrotheca (Mitt.) M. Alonso, M. J. Cano & J. A. Jiménez; C. hyalinoblastum (Broth.) M. Alonso, M. J. Cano & J. A. Jiménez; C. melanostomum (Mitt.) M. Alonso, M. J. Cano & J. A. Jiménez; C. orthodontum (Müll. Hal.) M. Alonso, M. J. Cano & J. A. Jiménez; C. sarawakense (Dixon) M. Alonso, M. J. Cano & J. A. Jiménez; and C. stenocarpum (Thér) M. Alonso, M. J. Cano & J. A. Jiménez). Moreover, 42 names are newly synonymized and a total of 74 new records for various countries are reported. Keys, descriptions, illustrations, photographs, and distribution data of each species are provided.

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