Tangible Assets to Improve Research Quality: A Meta Analysis Case Study

Author(s):  
Alessander Osorio ◽  
Marina Dias ◽  
Gerson Geraldo H. Cavalheiro
Author(s):  
Neville Owen ◽  
Ana Goode ◽  
Takemi Sugiyama ◽  
Mohammad Javad Koohsari ◽  
Genevieve Healy ◽  
...  

This chapter emphasizes the need for research that is designed and implemented explicitly with dissemination in mind. This is illustrated in relation to environmental and policy initiatives to influence physical activity through active transport, and through the example of initiatives to reduce workplace sitting. The other element of this chapter, the broad-reach intervention-dissemination case study of a health behavior-change program, highlights the need to maintain key elements of research quality in designing for dissemination, to the extent that is practically possible: a rigorous study design; the systematic tracking of implementation and related costs; and, the conduct of dose-response, maintenance and cost-effectiveness analyses. These examples of designing for dissemination illustrate not only the exciting opportunities for real-world dissemination research, but also the resourcefulness and commitment required for success.


2018 ◽  
Vol 29 (05) ◽  
pp. 401-407 ◽  
Author(s):  
Wei Yao ◽  
Kai Li ◽  
Zuopeng Wang ◽  
Jiahao Pei ◽  
Xiangqi Liu ◽  
...  

Objective To evaluate the outcome and safety of corticosteroids and vincristine (VCR) in the treatment of kaposiform hemangioendothelioma (KHE) and tufted angioma (TA). Materials and Methods Clinical studies involving corticosteroids and VCR therapies in treating KHE/TA were identified by using PubMed, Cochrane Library, OVID, EBSCO, CNKI, VIP, and Wanfang databases from their establishment date to December 2017. Randomized controlled trials, case–control, or case series with more than five cases were included. The following data were extracted: study sample, demographics, responses rate, recurrence rate, and adverse reactions. Two reviewers completed screening and extraction. Methodological quality was evaluated with quality appraisal tool. Results A total of 266 studies were found, and 27 studies were finally included in this research; quality of all studies was low. Seven studies with a total of 123 participants, which compared the effect of systemic corticosteroids with that of VCR, were performed for the meta-analysis. The results indicated that the effect of VCR was significantly higher than that of corticosteroids (relative risk [RR] = 2.08, 95% confidence interval [CI]: 1.38–3.16). The recurrence rate of VCR (11.1%) was lower than that of corticosteroids (50%), but there was no statistical difference between the two therapies (p = 0.1312). The result of pooled adverse reactions response rate for VCR was 18.2%, significantly lower than that for corticosteroids, which was 52.0%. Conclusion The present profile shows that VCR is relatively more effective and safer in treating KHE/TA than corticosteroids are. So, we believe VCR could be used as a first-line medication agent in the treatment of KHE/TA.


2019 ◽  
Vol 9 (3) ◽  
pp. 487-510
Author(s):  
Sejla Almadi

Conceptual frameworks are conjectural/hypothetical research tools that are particularly important and widely used in the disciplined inquiry, including educational (technology) research. However, there is a lack of guidance on how to construct them. Hence, the objective of the current research was to provide a methodological perspective through a case study on how to develop such a framework for deductive research with a complex research subject. To this end, a five-step technique was constructed and implemented: text database, research panorama, authors’ network and thread, location, and definition. The case of Pygmalion effect was actual and significant as a recent meta-analysis found it to have an outstanding impact, among other leadership interventions, and relevant to educational research as it was first experimented in educational context. The conclusion found the five steps to be intertwined as they were built upon each other, carried the thread forward and opened it up deeper and closer to the research subject by each section. The errors and limitations involved uniqueness, availability, less is more, meaningfulness, approach, and space. Hence, the recommendations were defined as the regard for the complexity of the research subject and the approach to which the defined steps were delegated, the preliminary search on the most up-to-date academic papers on the subject, the only necessary number of collected sources and classes, the sense-making in implementing the steps, and the adaptation to longer essays, theses, or to prepare the foundation of research proposals.


2018 ◽  
Vol 1 (2) ◽  
pp. 174-185 ◽  
Author(s):  
Evan C. Carter ◽  
Michael E. McCullough

Recent discussions of the influence of publication bias and questionable research practices on psychological science have increased researchers’ interest in both bias-correcting meta-analytic techniques and preregistered replication. Both approaches have their strengths: For example, meta-analyses can quantitatively characterize the full body of work done in the field of interest, and preregistered replications can be immune to bias. Both approaches also have clear weaknesses: Decisions about which meta-analytic estimates to interpret tend to be controversial, and replications can be discounted for failing to address important methodological heterogeneity. Using the experimental literature on ego depletion as a case study, we illustrate a principled approach to combining information from meta-analysis with information from subsequently conducted high-quality replications. This approach (a) compels researchers to explicate their beliefs in meta-analytic conclusions (and also, when controversy arises, to defend the basis for those beliefs), (b) encourages consideration of practical significance, and (c) facilitates the process of planning replications by specifying the sample sizes necessary to have a reasonable chance of changing the minds of other researchers.


2018 ◽  
pp. 285-302
Author(s):  
Eliana Al Haddad ◽  
Hutan Ashrafian ◽  
Thanos Athanasiou
Keyword(s):  

2018 ◽  
pp. 263-284
Author(s):  
Sulbaran Marianny ◽  
Sousa Afonso ◽  
Bustamante-Lopez Leonardo
Keyword(s):  

2018 ◽  
pp. 249-261
Author(s):  
Bashar J. Qumseya ◽  
Michael Wallace
Keyword(s):  

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