Over the last decade age-related dementias emerged as a significant health concern for Indigenous populations in Canada. Current research suggest that Indigenous communities hold culturally grounded understandings of dementia that are important in determining health services use and needs. This chapter combines a cultural safety framework with a health equity lens to discuss Indigenous dementia care needs in rural and remote Indigenous communities. Based on qualitative ethnographic data from Canada supported by published accounts of Indigenous experiences with dementia and dementia care internationally, we discuss promising approaches grounded in cultural safety aimed at improving prevention, diagnosis and care practices. Developing Indigenous specific care tools and adapting best practice mainstream approaches to care to adequately address cultural frameworks for dementia and the impacts of colonial trauma are necessary steps in providing decolonized, culturally safe care for Indigenous patients and fundamental to health equity.