Weakly Supervised Retinal Detachment Segmentation Using Deep Feature Propagation Learning in SD-OCT Images

Purpose: This article characterizes widefield fundus autofluorescence (WF-FAF) patterns in retinoschisis (RS), retinal detachment (RD), and combined retinoschisis-detachment (RS/RD), and to correlate them with spectral-domain optical coherence tomography (SD-OCT) findings. Methods: A retrospective case series of 13 eyes with senile RS, RD, or RS/RD is presented. One eye underwent imaging of 2 areas within the retina, resulting in 14 data points. Independent, masked graders classified pathology on SD-OCT as RS, RD, or RS/RD and graded WF-FAF images for either hypoautofluorescent areas or mixed autofluorescence (AF) (hyper-AF, iso-AF, hyper-AF with hypo-AF, hyper-AF with iso-AF, or hypo-AF with iso-AF). Results: There was no statistically significant correlation between the autofluorescence pattern and the type of retinal abnormality ( P = .74). Conclusions: High variability was found in the characterization of WF-FAF in patients with RS and RD. SD-OCT remains the criterion-standard imaging modality in distinguishing RS from RD in clinically ambiguous cases.

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Weakly Supervised Localization Using Deep Feature Maps

Computer Vision – ECCV 2016 - Lecture Notes in Computer Science ◽

10.1007/978-3-319-46448-0_43 ◽

2016 ◽

pp. 714-731 ◽

Cited By ~ 21

Author(s):

Archith John Bency ◽

Heesung Kwon ◽

Hyungtae Lee ◽

S. Karthikeyan ◽

B. S. Manjunath

Keyword(s):

Feature Maps ◽

Deep Feature ◽

Weakly Supervised

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Persistent Subretinal Fluid Mimicking Central Serous Retinopathy after Scleral Buckling Surgery: Possible Vortex Vein Compression Role

European Journal of Ophthalmology ◽

10.5301/ejo.5000876 ◽

2017 ◽

Vol 27 (2) ◽

pp. e54-e56 ◽

Cited By ~ 2

Author(s):

Chiara Giuffrè ◽

Adriano Carnevali ◽

Marco Codenotti ◽

Eleonora Corbelli ◽

Luigi A. De Vitis ◽

...

Keyword(s):

Retinal Detachment ◽

Indocyanine Green Angiography ◽

Serous Retinal Detachment ◽

Subretinal Fluid ◽

Scleral Buckling ◽

Central Serous Retinopathy ◽

Retinal Detachment Surgery ◽

Encircling Band ◽

Vortex Vein ◽

Sd Oct

Purpose To describe the case of a woman who developed persistent subretinal fluid in the macular region after the placement of encircling band for retinal detachment surgery, possibly due to vortex vein compression. Methods Case report. Results A 66-year-old woman diagnosed with central serous retinopathy presented with poor vision and metamorphopsia in the left eye (LE). Her visual acuity had deteriorated to 20/100 in LE after retinal detachment surgery with scleral buckling 8 months before. Multimodal imaging including fundus autofluorescence and fluorescein angiography disclosed a gravitational hyperfluorescent area involving the macular region that appeared to originate from the superotemporal quadrant in correspondence with the buckling. This area corresponded to a serous retinal detachment on structural spectral-domain optical coherence tomography (SD-OCT). Interestingly, on indocyanine green angiography, the encircling band of the scleral buckling appeared located at the emergence of the superotemporal vortex vein. Based on these findings, the patient was diagnosed with gravitational serous retinal detachment secondary to vortex vein compression. Successful rapid visual recovery and decrease of retinal fluid on SD-OCT was achieved with prompt surgery of scleral buckling removal, confirming the diagnosis. Conclusions Choroidal veins can be obliterated during retinal detachment surgery, especially when retinal breaks are posterior to the equator. Indocyanine green angiography is the gold standard to study choroidal circulation and in our case allowed us to visualize the compression of the superotemporal vortex vein at the site of scleral buckling.

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Association of Spectral-Domain Optical Coherence Tomography Findings with Visual Outcome of Macula-Off Rhegmatogenous Retinal Detachment Surgery

Ophthalmologica ◽

10.1159/000381786 ◽

2015 ◽

Vol 234 (2) ◽

pp. 83-90 ◽

Cited By ~ 16

Author(s):

Hae Min Kang ◽

Sung Chul Lee ◽

Christopher Seungkyu Lee

Keyword(s):

Optical Coherence Tomography ◽

Retinal Detachment ◽

Rhegmatogenous Retinal Detachment ◽

Subretinal Fluid ◽

Visual Outcome ◽

Spectral Domain ◽

Optical Coherence ◽

Foveal Thickness ◽

Central Foveal Thickness ◽

Sd Oct

Purpose: To identify prognostic factors for the visual outcome for patients with macula-off rhegmatogenous retinal detachment (RRD). Methods: The medical records of 27 patients (27 eyes) with macula-off RRD were retrospectively investigated. In addition to clinical characteristics, spectral-domain optical coherence tomography (SD OCT) images were analyzed. Results: The central foveal thickness at baseline was 923 ± 499.5 µm, and the mean height of the subretinal fluid was 697.8 ± 463.6 µm. Dropout of backreflection at the fovea was detected on preoperative SD OCT in 8 patients (29.6%). The external limiting membrane was disrupted in 5 patients (18.5%) as was the photoreceptor integrity in 9 patients (33.3%) at 12 months. On multiple regression analysis, backreflection integrity was the only predictive factor for postoperative visual outcome (B = 0.179, p = 0.020). Conclusions: Backreflection integrity on preoperative SD OCT seems to be helpful in predicting the postoperative visual outcome in macula-off RRD patients.

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Deep feature mining in weakly supervised perception

10.14711/thesis-991012762369403412 ◽

2019 ◽

Author(s):

Ting Sun

Keyword(s):

Deep Feature ◽

Weakly Supervised ◽

Feature Mining

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Outcome and SD-OCT Macular Findings Following Surgery in Spared Macula Giant Retinal Tear Retinal Detachment.

Journal of Ophthalmic Science ◽

10.14302/issn.2470-0436.jos-19-2829 ◽

2019 ◽

Vol 2 (2) ◽

pp. 17-22

Author(s):

Eman Abo Taleb ◽

Manish p. Nagpal ◽

Navneet S. Mehrotra ◽

Raddhi Arya

Keyword(s):

Retinal Detachment ◽

P Value ◽

Scleral Buckle ◽

Poor Functional Outcome ◽

Retinal Tear ◽

Giant Retinal Tear ◽

Primary Surgery ◽

Corrected Visual Acuity ◽

Sd Oct

Purpose To study outcome and spectral domain optical coherence tomography (SD-OCT) macular findings in patients who underwent surgery for spared macula giant retinal tear (GRT) retinal detachment. Methods a retrospective study of 12 patients with spared macula giant retinal tear (GRT) retinal detachment who underwent vitrectomy (N=7), vitrectomy with an encircling scleral buckle (n=4) and scleral buckle (n=1) with at least 3 months follow up after silicon oil removal (SOR) . Post-SOR macular SD-OCT scans were studied in all eyes. Results Final reattachment achieved in all eyes with single primary surgery. Post-SOR SD-OCT macular finding was photoreceptors layer disruption in 6 eyes, epiretinal membrane (ERM) in 4 eyes, Macular hole in 1 eye and choroidal neovascularisation in 1 eye. Significant correlation found between final Best-Corrected Visual Acuity (BCVA) and macular pathology on SD-OCT p value (0.048). Conclusion SD-OCT plays a high role in diagnosis of macular alterations that can be associated with poor functional outcome in anatomically successful GRT surgery with spared macula pre-operatively.

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The Influence of Silicone Oil on the Ganglion Cell Complex After Pars Plana Vitrectomy for Rhegmatogenous Retinal Detachment

Current Pharmaceutical Design ◽

10.2174/1381612824666180813115438 ◽

2018 ◽

Vol 24 (29) ◽

pp. 3476-3493 ◽

Cited By ~ 5

Author(s):

Dorota Raczyńska ◽

Kamila Mitrosz ◽

Krystyna Raczyńska ◽

Leopold Glasner

Keyword(s):

Retinal Detachment ◽

Ganglion Cell ◽

Pars Plana Vitrectomy ◽

Silicone Oil ◽

Cell Complex ◽

Ganglion Cell Complex ◽

Pars Plana ◽

Silicone Oil Tamponade ◽

The Impact ◽

Sd Oct

Purpose: Pars plana vitrectomy (PPV) and silicone oil endotamponade have been used as a treatment in rhegmatogenous retinal detachment (RRD). Improvement in the modality of spectral-domain optical coherence tomography (SD-OCT) allows for the assessment of ganglion cell layer-inner plexiform layer (GCL-IPL) in the macular region. Information about the GCL-IPL status may be a response to the question as to why the visual recovery after PPV with silicone oil tamponade is incomplete. The aim of the study was to evaluate the impact of silicone oil on GCL-IPL and compare it with other endotamponade types such as Sulfur hexafluoride gas (SF6), Perfluoropropane gas (C3F8) used during PPV performed due to RRD. Patients and Methods: The study involved 57 eyes after PPV and 57 healthy, control eyes of patients with primary RRD who had undergone successful PPV. The patients were divided into three subgroups depending on the endotamponade type, and were tracked with complete ophthalmological examination during a period of 6 months. PPV with internal tamponade silicone oil, 24% SF6 or 14% C3F8 was performed. The medical records were reviewed and compared between the groups. Results: SD-OCT analysis detected a significant reduction of average GCL-IPL thickness and reduction of GCLIPL parameter in almost all examined sectors in the group with silicone oil endotamponade during all follow-up visits (P<0.05). The study showed a significant vision deterioration in the silicone oil group in comparison with the SF6 group on all follow-up visits (P<0.05). Conclusion: This is the first in vivo SD-OCT study describing the toxic effect of silicone oil endotamponade on GCL-IPL complex after PPV for RRD. The study confirmed that the GCL-IPL complex value can be a predictive factor for assessing the final visual acuity. SD-OCT should be recommended as a clinical standard in the followup treatment of patients after PPV for RRD, especially with the use of silicone oil endotamponade. Plain Language Summary: The aim of the study was to examine the impact of silicone oil on the ganglion cell complex. The ganglion cell is a neuron type located in the retina and takes part in transmitting visual information from the retina to the brain. Silicone oil is a substance used during eye surgery called pars plana vitrectomy. This tamponade type acts to hold the retina in a proper position. However, during the retinal detachment, which is the separation of the retina from the layer underneath, a reduction of neurons is observed. We decided to use a new technology device called SD-OCT to determine the thickness of the ganglion cell complex. We compared the impact of silicone oil with other tamponade types. We found that silicone oil causes a reduction in the ganglion cell complex. Moreover, we observed vision deterioration in eyes treated with a silicone oil tamponade. The research describes the toxic effect of silicone oil on ganglion cells. Ganglion cell values may be used to determine visual improvement or deterioration after eye surgery with silicone oil tamponade. SD-OCT should be a clinical standard in monitoring patients with silicone oil tamponade.

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Clinical and Spectral-Domain Optical Coherence Tomography Findings of Patients with Incomplete Visual Recovery after Anatomically Successful Retinal Detachment Surgery

Journal of Ophthalmology ◽

10.1155/2015/420401 ◽

2015 ◽

Vol 2015 ◽

pp. 1-5 ◽

Cited By ~ 1

Author(s):

Miltiadis K. Tsilimbaris ◽

Aikaterini Chalkia ◽

Chrysanthi Tsika ◽

Anastasios Anastasakis ◽

Georgios A. Kontadakis

Keyword(s):

Retinal Detachment ◽

Spectral Domain ◽

Strongly Correlated ◽

Visual Recovery ◽

Retinal Detachment Surgery ◽

Spectral Domain Oct ◽

Pars Plana ◽

Oct Imaging ◽

Sd Oct

Purpose. To identify causes of incomplete visual recovery in patients with anatomically successful retinal detachment surgery.Methods. This was a retrospective study of 61 eyes of 61 patients with at least 12-month follow-up and complete preoperative, intraoperative, and postoperative record. Postoperative visual acuity (VA) more than 0.18 logMAR was considered as incomplete visual recovery. Complete ophthalmic examination and Spectral-Domain OCT (SD-OCT) imaging were performed at last follow-up.Results. Twenty-nine eyes (47.5%) had a postoperative VA < 0.18 logMAR and 32 eyes (52.5%) had a postoperative VA ≥ 0.18 logMAR. Mean follow-up was 32.8 ± 17.3 months. Incomplete visual recovery was strongly correlated with presence of macular pathology (P= 0.002), a detached macula preoperatively (P= 0.02), retinotomy (P= 0.025), and pars plana vitrectomy and use of silicon oil as a tamponade agent (P= 0.009). Also, although there was a strong correlation between ellipsoid zone disruption and incomplete visual recovery, a distinct, more course pathology could be identified in all cases of poor visual recovery related to edema, thickening, or atrophy of the macula.Conclusion. The careful postoperative evaluation of the macula using biomicroscopy and SD-OCT can help in diagnosis of alterations that can be associated with incomplete visual recovery.

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Role of Concomitant Internal Limiting Membrane (ILM) Peeling during Rhegmatogenous Retinal Detachment (RRD) Surgery in Preventing Postoperative Epiretinal Membrane (ERM) Formation

Pakistan Journal of Medical Sciences ◽

10.12669/pjms.37.3.3576 ◽

2021 ◽

Vol 37 (3) ◽

Author(s):

Asaad Mahmood Syed ◽

Fawad Rizvi Syed ◽

Burhan Abdul Majid Khan ◽

Tanweer Hasan Khan

Keyword(s):

Visual Acuity ◽

Retinal Detachment ◽

Epiretinal Membrane ◽

Rhegmatogenous Retinal Detachment ◽

Internal Limiting Membrane ◽

Ilm Peeling ◽

Group A ◽

Group B ◽

Sd Oct

Objective: To investigate the role of concomitant Internal Limiting Membrane (ILM) peeling during surgery for macula off Rhegmatogenous Retinal Detachment (RRD) in preventing postoperative Epiretinal Membrane (ERM) formation; and its effect on the visual acuity. Methods: This was a prospective, quasi-experimental study conducted from August 2018 to July 2019 at LRBT Tertiary Eye Care hospital, Karachi. Fifty-six patients with macula off RRD were divided into groups A (with ILM peeling) and B (without ILM peeling) via non-probability convenience sampling. All patients underwent standard 3 ports pars plana vitrectomy with silicon oil tamponade. In Group-A, ILM was stained using 0.5% ICG. Patients were evaluated clinically and by spectral domain optical coherence tomography (SD-OCT), pre- and post-operatively. Main outcomes recorded were best corrected visual acuity (BCVA) and occurrence of ERM on SD-OCT. Results: There were 26 patients in Group-A and 30 patients in Group-B. At six months’ follow-up, ERM had not developed in any case in Group-A compared to five patients (16.7%) in Group-B. There was no statistical difference in mean BCVA change from baseline. Conclusion: ILM peeling during vitrectomy for RRD prevents the formation of macular ERM post-operatively. This may reduce the need of a second vitrectomy. However, visual outcomes were comparable to the non-ILM peeling vitrectomy. doi: https://doi.org/10.12669/pjms.37.3.3576 How to cite this:Mahmood SA, Rizvi SF, Khan BAM, Khan TH. Role of Concomitant Internal Limiting Membrane (ILM) Peeling During Rhegmatogenous Retinal Detachment (RRD) Surgery in Preventing Postoperative Epiretinal Membrane (ERM) Formation. Pak J Med Sci. 2021;37(3):---------. doi: https://doi.org/10.12669/pjms.37.3.3576 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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