Pharmacological Treatment of Patients with Personality Disorders

2021 ◽  
pp. 209-220
Author(s):  
Giuseppe Nicolò ◽  
Michele Procacci ◽  
Antonino Carcione
Keyword(s):  
Personality Disorders ◽  
Pharmacological Treatment

Pharmacological Treatment of Personality Disorders

1988 ◽  
Vol 11 (6) ◽  
pp. 493-499 ◽  
Author(s):  
Peter Tyrer ◽  
Nicholas Seivewright
Keyword(s):  
Personality Disorders ◽  
Pharmacological Treatment

The Fundamentals of Brain Neurotransmission

2018 ◽  
Author(s):  
Robert O. Friedel ◽  
Stephen M. Stahl
Keyword(s):  
Synaptic Transmission ◽  
Personality Disorders ◽  
Pharmacological Treatment ◽  
Brain Function ◽  
Mechanisms Of Action ◽  
Mood Stabilizers ◽  
Neurotransmitter Systems ◽  
Psychoactive Medications

This chapter outlines the fundamental principles underlying neuroscience, particularly as it relates to neurotransmission and neuropharmacology. It then reviews and synthesizes of the role of different neurochemical and neurotransmitter systems that underlie brain function and synaptic transmission, including GABA, glutamate, serotonin, dopamine, norepinephrine, acetylcholine, and histamine. In addition, it describes various psychoactive medications are used in the treatment of personality disorders, such as mood stabilizers and antipsychotics. Moreover, it describes how these agents target these systems by describing their different mechanisms of action. It provides a primer to better understand the pathophysiology and pharmacological treatment of personality disorders discussed in the book.

Tools & Resources: Impairment and Disability Web Sites

1999 ◽  
Vol 4 (6) ◽  
pp. 5-6
Keyword(s):  
Personality Disorder ◽  
Personality Disorders ◽  
Interpersonal Relationships ◽  
Web Sites ◽  
Outpatient Psychotherapy ◽  
Obsessive Compulsive ◽  
Not Otherwise Specified ◽  
Cluster B Personality Disorders ◽  
Clinically Significant ◽  
And Behavior

Abstract Personality disorders are enduring patterns of inner experience and behavior that deviate markedly from those expected by the individual's culture; these inflexible and pervasive patterns reflect issues with cognition, affectivity, interpersonal functioning and impulse control, and lead to clinically significant distress or impairment in social, occupational, or other important areas of functioning. The AMA Guides to the Evaluation of Permanent Impairment, Fourth Edition, defines two specific personality disorders, in addition to an eleventh condition, Personality Disorder Not Otherwise Specified. Cluster A personality disorders include paranoid, schizoid, and schizotypal personalities; of these, Paranoid Personality Disorder probably is most common in the legal arena. Cluster B personality disorders include antisocial, borderline, histrionic, and narcissistic personality. Such people may suffer from frantic efforts to avoid perceived abandonment, patterns of unstable and intense interpersonal relationships, an identity disturbance, and impulsivity. Legal issues that involve individuals with cluster B personality disorders often involve determination of causation of the person's problems, assessment of claims of harassment, and assessment of the person's fitness for employment. Cluster C personality disorders include avoidant, dependent, and obsessive-compulsive personality. Two case histories illustrate some of the complexities of assessing impairment in workers with personality disorders, including drug abuse, hospitalizations, and inpatient and outpatient psychotherapy.

Test-Retest Reliability of a Self-Report Questionnaire for DSM-IV and ICD-10 Personality Disorders

2000 ◽  
Vol 16 (1) ◽  
pp. 53-58 ◽  
Author(s):  
Hans Ottosson ◽  
Martin Grann ◽  
Gunnar Kullgren
Keyword(s):  
Personality Disorder ◽  
Anxiety Disorders ◽  
Personality Disorders ◽  
Clinical Sample ◽  
Self Report ◽  
Anxiety State ◽  
Short Term ◽  
Retest Reliability ◽  
Axis I ◽  
Test Retest Reliability

Summary: Short-term stability or test-retest reliability of self-reported personality traits is likely to be biased if the respondent is affected by a depressive or anxiety state. However, in some studies, DSM-oriented self-reported instruments have proved to be reasonably stable in the short term, regardless of co-occurring depressive or anxiety disorders. In the present study, we examined the short-term test-retest reliability of a new self-report questionnaire for personality disorder diagnosis (DIP-Q) on a clinical sample of 30 individuals, having either a depressive, an anxiety, or no axis-I disorder. Test-retest scorings from subjects with depressive disorders were mostly unstable, with a significant change in fulfilled criteria between entry and retest for three out of ten personality disorders: borderline, avoidant and obsessive-compulsive personality disorder. Scorings from subjects with anxiety disorders were unstable only for cluster C and dependent personality disorder items. In the absence of co-morbid depressive or anxiety disorders, mean dimensional scores of DIP-Q showed no significant differences between entry and retest. Overall, the effect from state on trait scorings was moderate, and it is concluded that test-retest reliability for DIP-Q is acceptable.

Factors of Impulsivity and Cluster B Personality Dimensions

2017 ◽  
Vol 38 (4) ◽  
pp. 203-210 ◽  
Author(s):  
Christopher M. Lootens ◽  
Christopher D. Robertson ◽  
John T. Mitchell ◽  
Nathan A. Kimbrel ◽  
Natalie E. Hundt ◽  
...  
Keyword(s):  
Personality Disorders ◽  
The Other ◽  
Diagnostic Classification ◽  
Personality Dimensions ◽  
Cluster B Personality Disorders ◽  
Classification And Treatment

Abstract. The goal of the present investigation was to expand the literature on impulsivity and Cluster B personality disorders (PDs) by conceptualizing impulsivity in a multidimensional manner. Two separate undergraduate samples (n = 223; n = 204) completed measures of impulsivity and Cluster B dimensions. Impulsivity was indeed predictive of Cluster B dimensions and, importantly, each PD scale exhibited a unique impulsivity profile. Findings for borderline PD scores were highly consistent across samples and strongly and positively associated with urgency and lack of perseverance, as expected. Findings for the other PD dimensions also exhibited a fair amount of consistency. Implications of these findings for diagnostic classification and treatment are discussed.

Cognitive Treatment of Personality Disorders:: Difficult Clients or Difficult Process?

2003 ◽  
Vol 48 (5) ◽  
pp. 657-660
Author(s):  
Lisa Wallner Samstag ◽  
J. Christopher Muran
Keyword(s):  
Personality Disorders ◽  
Cognitive Treatment

A Science of Personality Disorders?

1990 ◽  
Vol 35 (12) ◽  
pp. 1164-1165
Author(s):  
Theodore Millon
Keyword(s):  
Personality Disorders
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