Interventional Radiology Therapies for Intrahepatic Cholangiocarcinoma

Diagnosis and Management of Cholangiocarcinoma ◽

10.1007/978-3-030-70936-5_18 ◽

2021 ◽

pp. 397-411

Author(s):

Thomas J. An ◽

Eric Wehrenberg-Klee

Keyword(s):

Interventional Radiology ◽

Intrahepatic Cholangiocarcinoma

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Interventional Radiology Management of Unresectable Intrahepatic Cholangiocarcinoma

Biliary Tract and Gallbladder Cancer - Medical Radiology ◽

10.1007/978-3-642-40558-7_13 ◽

2014 ◽

pp. 201-223

Author(s):

Adam D. Talenfeld ◽

Daniel J. Holzwanger ◽

David C. Madoff

Keyword(s):

Interventional Radiology ◽

Intrahepatic Cholangiocarcinoma ◽

Radiology Management

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Image-Guided Local Treatment for Unresectable Intrahepatic Cholangiocarcinoma—Role of Interventional Radiology

Journal of Clinical Medicine ◽

10.3390/jcm10235574 ◽

2021 ◽

Vol 10 (23) ◽

pp. 5574

Author(s):

Matthias P. Fabritius ◽

Najib Ben Khaled ◽

Wolfgang G. Kunz ◽

Jens Ricke ◽

Max Seidensticker

Keyword(s):

Interventional Radiology ◽

Local Recurrence ◽

Intrahepatic Cholangiocarcinoma ◽

Treatment Options ◽

Local Treatment ◽

Locoregional Treatment ◽

Hepatic Reserve ◽

Small Patient ◽

Initial Resection

Intrahepatic cholangiocarcinoma is a highly aggressive malignancy with an increasing incidence in recent years. Prognosis is poor and most patients are not eligible for resection at the time of initial diagnosis due to the anatomic location, inadequate hepatic reserve, limiting comorbidities or metastatic disease. Several locoregional therapies from the field of interventional radiology exist for patients who are not amenable for surgery, or in case of local recurrence as a single treatment modality or combined with systemic treatment. To date, evidence is limited, with most conclusions drawn from single-center studies with small patient cohorts, often treated in the salvage situation or for local recurrence after initial resection. Nevertheless, the results are promising and suggest a survival benefit in selected patients. This narrative review focuses on the use of different locoregional treatment options for intrahepatic cholangiocarcinoma.

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