Intracranial Aneurysm Rupture Prediction with Computational Fluid Dynamics Point Clouds

AbstractComputational fluid dynamics (CFD) has been studied as a tool for the stratification of aneurysm rupture risk. We performed CFD analysis in a patient operated on for a ruptured anterior communicating artery aneurysm. The point of rupture was identified during surgery. The aneurysm and blood vessels were segmented from computed tomography angiography to prepare a model for simulations. We found that the streamlines showed a concentrated inflow jet directed straight at the rupture point, and high wall shear stress was found at the point of rupture in the aneurysm sac. Thus specific local hemodynamics may be indicative of the aneurysm rupture site.

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Computational fluid dynamics as a risk assessment tool for aneurysm rupture

Neurosurgical FOCUS ◽

10.3171/2019.4.focus19189 ◽

2019 ◽

Vol 47 (1) ◽

pp. E12 ◽

Cited By ~ 8

Author(s):

Yuichi Murayama ◽

Soichiro Fujimura ◽

Tomoaki Suzuki ◽

Hiroyuki Takao

Keyword(s):

Fluid Dynamics ◽

Computational Fluid Dynamics ◽

Clinical Decision Making ◽

Assessment Tool ◽

Clinical Decision ◽

Aneurysm Rupture ◽

Hemodynamic Parameters ◽

Rupture Risk ◽

Clinical Role ◽

Risk Of Rupture

OBJECTIVEThe authors reviewed the clinical role of computational fluid dynamics (CFD) in assessing the risk of intracranial aneurysm rupture.METHODSA literature review was performed to identify reports on CFD assessment of aneurysms using PubMed. The usefulness of various hemodynamic parameters, such as wall shear stress (WSS) and the Oscillatory Shear Index (OSI), and their role in aneurysm rupture risk analysis, were analyzed.RESULTSThe authors identified a total of 258 published articles evaluating rupture risk, growth, and endovascular device assessment. Of these 258 articles, 113 matching for CFD and hemodynamic parameters that contribute to the risk of rupture (such as WSS and OSI) were identified. However, due to a lack of standardized methodology, controversy remains on each parameter’s role.CONCLUSIONSAlthough controversy continues to exist on which risk factors contribute to predict aneurysm rupture, CFD can provide additional parameters to assess this rupture risk. This technology can contribute to clinical decision-making or evaluation of efficacy for endovascular methods and devices.

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3D Modeling of Blood Flow in Simulated Abdominal Aortic Aneurysm

Vascular and Endovascular Surgery ◽

10.1177/15385744211012926 ◽

2021 ◽

pp. 153857442110129

Author(s):

Mauricio Gonzalez-Urquijo ◽

Raul Garza de Zamacona ◽

Ana Karen Martinez Mendoza ◽

Miranda Zamora Iribarren ◽

Erika Garza Ibarra ◽

...

Keyword(s):

Fluid Dynamics ◽

Computational Fluid Dynamics ◽

Shear Stress ◽

Abdominal Aortic Aneurysm ◽

Aortic Aneurysm ◽

Abdominal Aortic Aneurysms ◽

Aneurysm Rupture ◽

Aortic Aneurysms ◽

Abdominal Aortic ◽

Computer Aided

Background: Besides biological factors, abdominal aortic aneurysm rupture is also caused by mechanical parameters, which are constantly affecting the wall’s tissue due to their abnormal values. The ability to evaluate these parameters could vastly improve the clinical treatment of patients with abdominal aortic aneurysms. The objective of this study was to develop and demonstrate a methodology to analyze the fluid dynamics that cause the wall stress distribution in abdominal aortic aneurysms, using accurate 3D geometry and a realistic, nonlinear, elastic biomechanical model using a computer-aided software. Methods: The geometry of the abdominal aortic aneurysm; was constructed on a 3D scale using computer-aided software SolidWorks (Dassault Systems SolidWorksCorp., Waltham MA). Due to the complex nature of the abdominal aortic aneurysm geometry, the physiological forces and constraints acting on the abdominal aortic aneurysm wall were measured by using a simulation setup using boundary conditions and initial conditions for different studies such as finite element analysis or computational fluid dynamics. Results: The flow pattern showed an increase velocity at the angular neck, followed by a stagnated flow inside the aneurysm sack. Furthermore, the wall shear stress analysis showed to focalized points of higher stress, the top and bottom of the aneurysm sack, where the flow collides against the wall. An increase of the viscosity showed no significant velocity changed but results in a slight increase in overall pressure and wall shear stress. Conclusions: Conducting computational fluid dynamics modeling of the abdominal aortic aneurysm using computer-aided software SolidWorks (Dassault Systems SolidWorksCorp., Waltham MA) proves to be an insightful approach for the clinical setting. The careful consideration of the biomechanics of the abdominal aortic aneurysm may lead to an improved, case-specific prediction of the abdominal aortic aneurysm rupture potential, which could significantly improve the clinical management of these patients.

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Pressure Increase after Stent Intervention Treatment for an Aneurysm Accompanied by a Stenosis

International Journal of Computational Methods ◽

10.1142/s0219876218420100 ◽

2019 ◽

Vol 16 (03) ◽

pp. 1842010 ◽

Cited By ~ 1

Author(s):

Wenyu Fu ◽

Aike Qiao

Keyword(s):

Fluid Dynamics ◽

Computational Fluid Dynamics ◽

Treatment Plan ◽

Giant Aneurysm ◽

Aneurysm Rupture ◽

Pressure Increase ◽

The Third ◽

Intervention Treatment ◽

Dynamics Analyses

Computational fluid dynamics analyses were performed on three models which have a giant aneurysm with or without a stenosis. The first is a model with an aneurysm (no stenosis and no stent), the second is a model with a preaneurysm stenosis, and the third is a model with an aneurysm implanted with a stent. The increase in pressure in aneurismal sac caused by a 50% stenosis is about 10.3[Formula: see text]mmHg at peak systole (comparison between the second model and the first model). It must pay attention to the increase of the pressure for the patient which has an aneurysm accompanied by a stenosis when making the treatment plan. Otherwise, it may cause the aneurysm rupture.

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