Simulation of the Dynamic and Thermodynamic Structure and Microphysical Evolution of a Squall Line in South China

A squall line that occurred in south China on 31 March 2014 was simulated with the Weather Research and Forecasting model. The microphysical processes had an important influence on the dynamic and thermodynamic structure of the squall line. The process of water vapor condensation (PCC+) provided heat for the ascending movement inside the squall line. The forward movement of the heating area of PCC+ was an important reason for the squall line’s tilting. The convergence of the outflow of the cold pool and the warm and wet air constantly triggered new convection cells in the front of the cold pool, which made the squall line propagate forwards. The cooling process of graupel melting into rain corresponded closely with the rear inflow jet. During the mature period of the squall line, the effect of cooling strengthened the rear inflow jet. This promoted low-layer inflow and a convective ascending motion, thus further promoting the development of the squall line system. During the decay period, the strong backflow center of the stratospheric region cut off the forward inflow of the middle and low layer towards the high layer, and cooperated with the cold pool to cut off the warm and wet air transport of the low layer, making the system decline gradually.

A Dissipation Function–Based Method for Calculating the Energy Loss of Intracranial Aneurysms

At present, the energy loss (EL) mechanism of intracranial aneurysm (IA) rupture is explored based on the global EL calculated by Bernoulli equation, but the details of EL are still unclear. This study aimed to explore the temporal and spatial characteristics of EL of IAs and reveal its mechanism. A novel method for calculating the EL of IAs based on dissipation function (DF) was proposed. DF was derived from the differential form of the energy equation and reflected the irreversible conversion from mechanical energy to internal energy caused by the friction between the fluid micelles. Eight sidewall IAs located at the posterior communicating segment of the internal carotid artery were collected; the three-dimensional (3D) geometric models of IAs were established employing image segmentation and 3D reconstruction. Computational fluid dynamics was applied to obtain hemodynamic parameters of IAs. The temporal and spatial characteristics of EL of IAs were achieved utilizing our proposed method. The simulation results indicated that EL occurred mainly in the boundary layer and the region adjacent to high-velocity inflow jet, EL increased rapidly during cardiac systole and reached its maximum at end-systolic phase and then decreased gradually during diastole until the end of cardiac cycle. The proposed method achieved some improvements over the traditional Bernoulli equation–based method by acquiring the temporal and spatial characteristics of EL, and it could provide insights into the EL of IAs and contribute to further rupture mechanism investigation.

Impacts of Stochastic Mixing in Idealized Convection-Permitting Simulations of Squall Lines

This study investigates impacts of altering subgrid-scale mixing in “convection-permitting” kilometer-scale horizontal-grid-spacing (Δh) simulations by applying either constant or stochastic multiplicative factors to the horizontal mixing coefficients within the Weather Research and Forecasting Model. In quasi-idealized 1-km Δh simulations of two observationally based squall-line cases, constant enhanced mixing produces larger updraft cores that are more dilute at upper levels, weakens the cold pool, rear-inflow jet, and front-to-rear flow of the squall line, and degrades the model’s effective resolution. Reducing mixing by a constant multiplicative factor has the opposite effect on all metrics. Completely turning off parameterized horizontal mixing produces bulk updraft statistics and squall-line mesoscale structure closest to an LES “benchmark” among all 1-km simulations, although the updraft cores are too undilute. The stochastic mixing scheme, which applies a multiplicative factor to the mixing coefficients that varies stochastically in time and space, is employed at 0.5-, 1-, and 2-km Δh. It generally reduces midlevel vertical velocities and enhances upper-level vertical velocities compared to simulations using the standard mixing scheme, with more substantial impacts at 1- and 2-km Δh compared to 0.5-km Δh. The stochastic scheme also increases updraft dilution to better agree with the LES for one case, but has less impact on the other case. Stochastic mixing acts to weaken the cold pool but without a significant impact on squall-line propagation. It also does not affect the model’s overall effective resolution unlike applying constant multiplicative factors to the mixing coefficients.

On the Modal Analysis of Blood Flow Dynamics in Brain Aneurysms

Complex, unstable inflow jet has been linked to aneurysm growth and rupture. However, methodologies to characterize this inflow jet have not been well established. Our previous works (Le et al., J. Biomech. Engr., 2010 and Le et al., Annals Biomedical Eng., 2013) have shown a possible transition from the stable mode (cavity) to the unstable mode (vortex ring) of this jet. We have proposed the use of a non-dimensional index called Aneurysm Number to characterize this transition (Le et al., 2013). However, the quantification of such a transition is lacking. Currently, there have no efforts in quantifying unstable flows in intracranial aneurysms, which is essential in stratifying rupture risks. In this work, the aneurysmal geometries from three patients at Sanford Health, North Dakota are reconstructed from Magnetic Resonance Angiogram and Digital Subtraction Angiogram data. Using our in-house CFD code (Virtual Flow Simulator), high-resolution flow data is obtained via numerical simulation. We perform modal analysis of blood flow dynamics for these cases using Proper Orthogonal Decomposition. Our results show that there are up to five dominant modes in the flow arising from the interaction of the incoming jet and the aneurysm dome. The spatial distribution of these modes reflect the characteristics of the inflow jet and can be used to quantify flow unsteadiness. Future works will be needed to apply the same procedure for a larger population of patients to examine its relevance in clinical practice.

Spatiotemporal Evolution of the Microphysical and Thermodynamic Characteristics of the 20 June 2015 PECAN MCS

This study examines microphysical and thermodynamic characteristics of the 20 June 2015 mesoscale convective system (MCS) observed during the Plains Elevated Convection At Night (PECAN) experiment, specifically within the transition zone (TZ), enhanced stratiform rain region (ESR), anvil region, melting layer (ML), and the rear inflow jet (RIJ). Analyses are developed from airborne optical array probe data and multiple-Doppler wind and reflectivity syntheses using data from the airborne NOAA Tail Doppler Radar (TDR) and ground-based Weather Surveillance Radar-1988 Doppler (WSR-88D) radars. Seven spiral ascents/descents of the NOAA P-3 aircraft were executed within various regions of the 20 June MCS. Aggregation modified by sublimation was observed in each MCS region, regardless of whether the sampling was within the RIJ. Sustained sublimation and evaporation of precipitation in subsaturated layers led to a trend of downward moistening across the ESR spirals, with greater degrees of subsaturation maintained when in the vicinity of the descending RIJ. In all cases where melting was observed, the ML acted as a prominent thermodynamic boundary, with differing rates of change in temperature and relative humidity above and below the ML. Two spiral profiles coincident with the rear inflow notch provided unique observations within the TZ and were interpreted in the context of similar observations from the 29 June 2003 Bow Echo and Mesoscale Convective Vortex Experiment MCS. There, sublimation cooling and enhanced descent within the RIJ allowed ice particles to survive to temperatures as warm as +6.8°C before completely sublimating/evaporating.

Relationship between haemodynamic changes and outcomes of intracranial aneurysms after implantation of the pipeline embolisation device: a single centre study

Background Intracranial aneurysms are increasingly being treated by the placement of flow diverters; however, the factors affecting the outcome of aneurysms treated using flow diverters remain unclarified. Methods The present study investigated 94 aneurysms treated with pipeline embolisation device placement, and used a computational fluid dynamics method to explore the factors influencing the outcome of aneurysms. Results Seventy-six completely occluded aneurysms and 18 incompletely occluded aneurysms were analysed. Before treatment, inflow jets were found in 13 (72.2%) aneurysms in the incompletely occluded group and 34 (44.7%) in the completely occluded group ( P = 0.292). After deployment of the pipeline embolisation device, inflow jets remained in nine (50%) aneurysms in the incompletely occluded group and nine (11.8%) in the completely occluded group ( P = 0.001). In the incompletely occluded group, regions with inflow jets after treatment corresponded with the patent areas shown on follow-up digital subtraction angiography. The mean reduction ratios of velocity in the whole aneurysm and on the neck plane were lower in the incompletely occluded than in the completely occluded group ( P = 0.003; P = 0.017). Multivariate analysis revealed that the only independent risk factors for incomplete aneurysm occlusion were the reduction ratios of velocity (in the whole aneurysm, threshold 0.362, P = 0.005; on the neck plane, threshold 0.273, P = 0.015). Conclusions After pipeline embolisation device placement, reduction ratios of velocity in the whole aneurysm of less than 0.362 and on the neck plane of less than 0.273 are significantly associated with a greater risk of aneurysm incomplete occlusion. In addition, the persistence of inflow jets in aneurysms is associated with incomplete occlusion in the inflow jet area.

Origins of Vorticity in a Simulated Tornadic Mesovortex Observed during PECAN on 6 July 2015

To better understand and forecast nocturnal thunderstorms and their hazards, an expansive network of fixed and mobile observing systems was deployed in the summer of 2015 for the Plains Elevated Convection at Night (PECAN) field experiment to observe low-level jets, convection initiation, bores, and mesoscale convective systems. On 5–6 July 2015, mobile radars and ground-based surface and upper-air profiling systems sampled a nocturnal, quasi-linear convective system (QLCS) over South Dakota. The QLCS produced several severe wind reports and an EF-0 tornado. The QLCS and its environment leading up to the mesovortex that produced this tornado were well observed by the PECAN observing network. In this study, observations from radiosondes, Doppler radars, and aircraft are assimilated into an ensemble analysis and forecasting system to analyze this event with a focus on the development of the observed tornadic mesovortex. All ensemble members simulated low-level mesovortices with one member in particular generating two mesovortices in a manner very similar to that observed. Forecasts from this member were analyzed to examine the processes increasing vertical vorticity during the development of the tornadic mesovortex. Cyclonic vertical vorticity was traced to three separate airstreams: the first from southerly inflow that was characterized by tilting of predominantly crosswise horizontal vorticity along the gust front, the second from the north that imported streamwise horizontal vorticity directly into the low-level updraft, and the third from a localized downdraft/rear-inflow jet in which the horizontal vorticity became streamwise during descent. The cyclonic vertical vorticity then intensified rapidly through intense stretching as the parcels entered the low-level updraft of the developing mesovortex.

Entry remnants in flow-diverted aneurysms: Does branch geometry influence aneurysm closure?

Objective Numerous studies have suggested a relationship between delayed occlusion of intracranial aneurysms treated with the Pipeline Embolization Device (PED) and the presence of an incorporated branch. However, in some cases, flow diversion may still be the preferred treatment option. This study sought to determine whether geometric factors pertaining to relative size and angulation of branch vessel(s) can be measured in a reliable fashion and whether they are related to occlusion rates. Methods Eighty aneurysms treated at a single neurovascular center from November 2008 to June 2014 were identified. Two blinded raters prospectively reviewed the imaging performed at the time of the procedure and measured the following geometric variables: inflow jet/incorporated branch direction angle and branch artery/ parent artery ratio. Delayed occlusion was defined as the absence of complete aneurysmal occlusion at one year. Analysis was performed using logistic regression and intra-class correlation co-efficient (ICC). Results Twenty-four (30%) aneurysms with 28 incorporated branches were identified. A trend toward higher inflow jet/incorporated branch direction angle was found in the group of aneurysms demonstrating delayed occlusion when compared to the group with complete occlusion. ICC revealed high correlation. Overall lower one-year occlusion rates of 53% versus 73% for aneurysms with and without incorporated branches, respectively, were also noted. Conclusions The presence of an incorporated branch conferred a 20% absolute risk increase for delayed aneurysmal occlusion. Incorporated branches with a larger angle between the inflow jet and the incorporated branch direction exhibited a trend toward lower occlusion rates. This might be further investigated using a multicenter approach in conjunction with other potentially relevant clinical and angiographic variables.