Enteral Nutrition in Preterm Neonates

2021 ◽  
pp. 65-85
Author(s):  
Gianluca Terrin ◽  
Maria Di Chiara ◽  
Giulia Sabatini ◽  
Thibault Senterre ◽  
Mario De Curtis
Keyword(s):  
Enteral Nutrition ◽  
Preterm Neonates

Enteral Nutrition in Preterm Neonates

2015 ◽  
pp. 53-71 ◽  
Author(s):  
Gianluca Terrin ◽  
Thibault Senterre ◽  
Jacques Rigo ◽  
Mario De Curtis
Keyword(s):  
Enteral Nutrition ◽  
Preterm Neonates

scholarly journals Benefits of probiotics on enteral nutrition in preterm neonates: a systematic review

2014 ◽  
Vol 100 (6) ◽  
pp. 1508-1519 ◽  
Author(s):  
Gayatri Athalye-Jape ◽  
Girish Deshpande ◽  
Shripada Rao ◽  
Sanjay Patole
Keyword(s):  
Systematic Review ◽  
Enteral Nutrition ◽  
Preterm Neonates

Transition from parenteral to enteral nutrition induces immediate diet-dependent gut histological and immunological responses in preterm neonates

2011 ◽  
Vol 301 (3) ◽  
pp. G435-G445 ◽  
Author(s):  
Jayda Siggers ◽  
Per T. Sangild ◽  
Tim K. Jensen ◽  
Richard H. Siggers ◽  
Kerstin Skovgaard ◽  
...  
Keyword(s):  
Enteral Nutrition ◽  
Preterm Infants ◽  
Enteral Feeding ◽  
Digestive Enzyme ◽  
Immune Defense ◽  
Preterm Neonates ◽  
Gene Expressions ◽  
Altered Expression ◽  
Histopathological Lesions ◽  
Induced Changes

Necrotizing enterocolitis (NEC) in preterm infants develops very rapidly from a mild intolerance to enteral feeding into intestinal mucosal hemorrhage, inflammation, and necrosis. We hypothesized that immediate feeding-induced gut responses precede later clinical NEC symptoms in preterm pigs. Fifty-six preterm pigs were fed total parenteral nutrition (TPN) for 48 h followed by enteral feeding for 0, 8, 17, or 34 h with either colostrum (Colos, n = 20) or formula (Form, n = 31). Macroscopic NEC lesions were detected in Form pigs throughout the enteral feeding period (20/31, 65%), whereas most Colos pigs remained protected (1/20, 5%). Just 8 h of formula feeding induced histopathological lesions, as evidenced by capillary stasis and necrosis, epithelial degeneration, edema, and mucosal hemorrhage. These immediate formula-induced changes were paralleled by decreased digestive enzyme activities (lactase and dipeptidylpeptidase IV), increased nutrient fermentation, and altered expression of innate immune defense genes such as interleukins (IL-1α, IL-6, IL-18), nitric oxide synthetase, tight junction proteins (claudins), Toll-like receptors (TLR-4), and TNF-α. In contrast, the first hours of colostrum feeding induced no histopathological lesions, increased maltase activity, and induced changes in gene expressions related to tissue development. Total bacterial density was high after 2 days of parenteral feeding and was not significantly affected by diet (colostrum, formula) or length of enteral feeding (8–34 h), except that a few bacterial groups ( Clostridium, Enterococcus, Streptococcus species) increased with time. We conclude that a switch from parenteral to enteral nutrition rapidly induces diet-dependent histopathological, functional, and proinflammatory insults to the immature intestine. Great care is required when introducing enteral feeds to TPN-fed preterm infants, particularly when using formula, because early feeding-induced insults may predispose to NEC lesions that are difficult to revert by later dietary or medical interventions.

Developmental care approaches for mitigating stress in preterm neonates in the neonatal intensive care unit: A systematic review.

2018 ◽  
Vol 11 (2) ◽  
pp. 117-131 ◽  
Author(s):  
Nathália de Figueiredo Silva ◽  
Maria Beatriz Martins Linhares ◽  
Cláudia Maria Gaspardo
Keyword(s):  
Systematic Review ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care ◽  
Preterm Neonates ◽  
Developmental Care

Genomic risk factors for bronchopulmonary dysplasia (BPD) in preterm neonates

2012 ◽  
Vol 224 (07) ◽  
Author(s):  
L Gortner ◽  
P Ahnert ◽  
W Göpel ◽  
P Nürnberg
Keyword(s):  
Risk Factors ◽  
Bronchopulmonary Dysplasia ◽  
Preterm Neonates ◽  
Genomic Risk

Immediate Effects of Phototherapy on Sleep of Very Preterm Neonates: An Observational Study

2015 ◽  
Vol 46 (S 01) ◽  
Author(s):  
M. Cremer ◽  
K. Jost ◽  
S. Schulzke ◽  
P. Weber ◽  
A. Datta
Keyword(s):  
Observational Study ◽  
Preterm Neonates ◽  
Very Preterm
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