scholarly journals Coordinating Multi-party Vehicle Routing with Location Congestion via Iterative Best Response

Author(s):  
Waldy Joe ◽  
Hoong Chuin Lau
Author(s):  
Karl Widerquist ◽  
Grant S. McCall

Earlier chapters of this book found that the Hobbesian hypothesis is false; the Lockean proviso is unfulfilled; contemporary states and property rights systems fail to meet the standard that social contract and natural property rights theories require for their justification. This chapter assesses the implications of those findings for the two theories. Section 1 argues that, whether contractarians accept or reject these findings, they need to clarify their argument to remove equivocation. Section 2 invites efforts to refute this book’s empirical findings. Section 3 discusses a response open only to property rights theorists: concede this book’s empirical findings and blame government failure. Section 4 considers the argument that this book misidentifies the state of nature. Section 5 considers a “bracketing strategy,” which admits that observed stateless societies fit the definition of the state of nature, but argues that they are not the relevant forms of statelessness today. Section 6 discusses the implications of accepting both the truth and relevance of the book’s findings, concluding that the best response is to fulfil the Lockean proviso by taking action to improve the lives of disadvantaged people.


2015 ◽  
Vol 24 (3) ◽  
pp. 379-382
Author(s):  
Tadahisa Inoue ◽  
Hitoshi Sano ◽  
Takashi Mizushima ◽  
Hirotada Nishie ◽  
Hiroyasu Iwasaki ◽  
...  

We present the case of a Japanese man in his 60s with duodenal neuroendocrine carcinoma with distant metastases. Chemotherapy with irinotecan plus cisplatin was initiated as a first-line regimen. However, disease progression was observed after only two cycles. Therefore, amrubicin was administered as a second-line chemotherapy. The patient showed a long-term effect of amrubicin therapy, and the best response was a partial response after seven cycles. For duodenal neuroendocrine carcinoma, amrubicin therapy can be considered an effective treatment option as salvage chemotherapy.


Agrotek ◽  
2018 ◽  
Vol 3 (2) ◽  
Author(s):  
Baso Daeng

<em>The rate of conversion of paddy fields and irrigation water crisis suggest to consider the development of upland rice.� Empowerment of organic-based dryland done to increase rice, as well as environmental sustainability efforts.� The purpose of this experiment was to determine the effect of organic fertilizer residue to upland rice in the second growing season.� Experiments using a split-split plot design.� The main plot consisted of a dosage of 50% and 100% organic fertilizer in the first growing season.� Sub plot consisted of chicken manure (20 tons ha<sup>-1</sup>), <span style="text-decoration: underline;">Centrosema</span>� <span style="text-decoration: underline;">pubescens</span> (4.3 tons ha<sup>-1</sup>) + chicken manure (10 tons ha<sup>-1</sup>), and <span style="text-decoration: underline;">Thitonia</span> <span style="text-decoration: underline;">diversifolia</span> (4.3 tons ha<sup>-1</sup>) + chicken manure (10 tons ha<sup>-1</sup>).� Sub-sub plot consist of Danau Gaung and Batu Tegi varieties.� The different types of fertilizer had no effect on plant productivity.� The addition of <span style="text-decoration: underline;">Thitonia</span> <span style="text-decoration: underline;">diversifolia</span> gave a good effect on some growth variable and its resistance due pathogen attack.� Batu Tegi varieties are varieties that give the best response from an organic fertilizer.� Interaction between dosage, type of fertilizer, and varieties do not provide areal impact.</em>


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