Redox Signalling, Autophagy and Ageing

2021 ◽  
pp. 117-145
Author(s):  
Fatma Hussain ◽  
Umm-E-Ammara Warraich ◽  
Amer Jamil
Keyword(s):  
Redox Signalling

Redox signalling and miRNA function in cardiomyocytes

2009 ◽  
Vol 47 (1) ◽  
pp. 2-4 ◽  
Author(s):  
Alison C. Brewer ◽  
Ajay M. Shah
Keyword(s):  
Redox Signalling

scholarly journals Vascular targets of redox signalling in diabetes mellitus

Diabetologia ◽  
2002 ◽  
Vol 45 (4) ◽  
pp. 476-494 ◽  
Author(s):  
M. M. Spitaler ◽  
W. F. Graier
Keyword(s):  
Diabetes Mellitus ◽  
Redox Signalling

scholarly journals Control and dysregulation of redox signalling in the gastrointestinal tract

2018 ◽  
Vol 16 (2) ◽  
pp. 106-120 ◽  
Author(s):  
Eric L. Campbell ◽  
Sean P. Colgan
Keyword(s):  
Gastrointestinal Tract ◽  
Redox Signalling

CHAPTER 2. Oxidative Stress and Redox Signalling in the Parkinson’s Disease Brain

2017 ◽  
pp. 27-60
Author(s):  
Pablo Hernandez-Franco ◽  
Annandurai Anandhan ◽  
Rachel M. Foguth ◽  
Rodrigo Franco
Keyword(s):  
Oxidative Stress ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Redox Signalling

Thiol-Disulphide Redox Signalling/Control during the Life Cycle of Pathogenic Trypanosomatids

2021 ◽  
pp. 37-55
Author(s):  
Gabriela Specker ◽  
Lucía Piacenza ◽  
Rafael Radi ◽  
Marcelo A. Comini
Keyword(s):  
Life Cycle ◽  
Redox Signalling

scholarly journals Roles of Autophagy in Oxidative Stress

2020 ◽  
Vol 21 (9) ◽  
pp. 3289 ◽  
Author(s):  
Hyeong Rok Yun ◽  
Yong Hwa Jo ◽  
Jieun Kim ◽  
Yoonhwa Shin ◽  
Sung Soo Kim ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cell Death ◽  
Stress Responses ◽  
Basic Mechanism ◽  
Redox Signalling ◽  
Mitochondrial Ros ◽  
Related Stress ◽  
And Function ◽  
Catabolic Process

Autophagy is a catabolic process for unnecessary or dysfunctional cytoplasmic contents by lysosomal degradation pathways. Autophagy is implicated in various biological processes such as programmed cell death, stress responses, elimination of damaged organelles and development. The role of autophagy as a crucial mediator has been clarified and expanded in the pathological response to redox signalling. Autophagy is a major sensor of the redox signalling. Reactive oxygen species (ROS) are highly reactive molecules that are generated as by-products of cellular metabolism, principally by mitochondria. Mitochondrial ROS (mROS) are beneficial or detrimental to cells depending on their concentration and location. mROS function as redox messengers in intracellular signalling at physiologically low level, whereas excessive production of mROS causes oxidative damage to cellular constituents and thus incurs cell death. Hence, the balance of autophagy-related stress adaptation and cell death is important to comprehend redox signalling-related pathogenesis. In this review, we attempt to provide an overview the basic mechanism and function of autophagy in the context of response to oxidative stress and redox signalling in pathology.

Tetrahydrobiopterin: coupling nitric oxide and redox signalling in cardiovascular disease

2012 ◽  
Vol 56 (5-6) ◽  
pp. 322
Author(s):  
Keith M. Channon
Keyword(s):  
Nitric Oxide ◽  
Cardiovascular Disease ◽  
Redox Signalling
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