Role of Oxalobacter formigenes Colonization in Calcium Oxalate Kidney Stone Disease

2016 ◽  
pp. 77-84
Author(s):  
John Knight ◽  
Ross P. Holmes
Keyword(s):  
Calcium Oxalate ◽  
Kidney Stone ◽  
Stone Disease ◽  
Oxalobacter Formigenes ◽  
Kidney Stone Disease

scholarly journals 40 Years of Oxalobacter formigenes , a Gutsy Oxalate-Degrading Specialist

2021 ◽  
Author(s):  
Steven L. Daniel ◽  
Luke Moradi ◽  
Henry Paiste ◽  
Kyle D. Wood ◽  
Dean G. Assimos ◽  
...  
Keyword(s):  
Calcium Oxalate ◽  
Kidney Stone ◽  
Critical Role ◽  
Primary Hyperoxaluria ◽  
Severe Form ◽  
Stone Disease ◽  
Future Research ◽  
Oxalobacter Formigenes ◽  
Kidney Stone Disease ◽  
Degrading Bacterium

Oxalobacter formigenes , a unique anaerobic bacterium that relies solely on oxalate for growth, is a key oxalate-degrading bacterium in the mammalian intestinal tract. Degradation of oxalate in the gut by O. formigenes plays a critical role in preventing renal toxicity in animals that feed on oxalate-rich plants. The role of O. formigenes in reducing the risk of calcium oxalate kidney stone disease and oxalate nephropathy in humans is less clear, in part due to difficulties in culturing this organism, and the lack of studies which have utilized diets controlled in their content of oxalate. Herein, we review the literature on the 40 th anniversary of the discovery of O. formigenes , with a focus on its biology, its role in gut oxalate metabolism and calcium oxalate kidney stone disease, and potential areas of future research. Results from ongoing clinical trials utilizing O. formigenes in healthy volunteers and in patients with Primary Hyperoxaluria Type 1 (PH1), a rare but severe form of calcium oxalate kidney stone disease, will also be discussed. Information has been consolidated on O. formigenes strains and best practices to culture this bacterium, which should serve as a good resource for researchers.

A Porcine Model of Calcium Oxalate Kidney Stone Disease

2004 ◽  
Vol 171 (3) ◽  
pp. 1301-1303 ◽  
Author(s):  
NEIL S. MANDEL ◽  
JAMES D. HENDERSON ◽  
LINDA Y. HUNG ◽  
DAVID F. WILLE ◽  
JOHN H. WIESSNER
Keyword(s):  
Calcium Oxalate ◽  
Kidney Stone ◽  
Porcine Model ◽  
Stone Disease ◽  
Kidney Stone Disease

Factors Differentiating the Effectiveness of Polyprotic Acids as Inhibitors of Calcium Oxalate Crystallization in Kidney Stone Disease

2018 ◽  
Vol 18 (9) ◽  
pp. 5617-5627 ◽  
Author(s):  
Jihae Chung ◽  
Michael G. Taylor ◽  
Ignacio Granja ◽  
John R. Asplin ◽  
Giannis Mpourmpakis ◽  
...  
Keyword(s):  
Calcium Oxalate ◽  
Kidney Stone ◽  
Stone Disease ◽  
Calcium Oxalate Crystallization ◽  
Kidney Stone Disease

Prevalence of Hyperoxaluria in Idiopathic Calcium Oxalate Kidney Stone Disease

Nephron ◽  
1983 ◽  
Vol 35 (1) ◽  
pp. 11-14 ◽  
Author(s):  
B. Baggio ◽  
G. Gambaro ◽  
S. Favaro ◽  
A. Borsatti
Keyword(s):  
Calcium Oxalate ◽  
Kidney Stone ◽  
Stone Disease ◽  
Kidney Stone Disease

scholarly journals The role of fluid intake in the prevention of kidney stone disease: A systematic review over the last two decades

2020 ◽  
Vol 46 (Supp1) ◽  
pp. S92-S103
Author(s):  
Kithmini Nadeeshani Gamage ◽  
◽  
Enakshee Jamnadass ◽  
Sadaf Karim Sulaiman ◽  
Amelia Pietropaolo ◽  
...  
Keyword(s):  
Systematic Review ◽  
Kidney Stone ◽  
Fluid Intake ◽  
Stone Disease ◽  
Kidney Stone Disease

Role of urinary biomarkers for diagnosis and prognosis of kidney stone disease

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Anna Brewin ◽  
Sheshadri Sriprasad ◽  
Bhaskar K. Somani
Keyword(s):  
Kidney Stone ◽  
Stone Disease ◽  
Urinary Biomarkers ◽  
Kidney Stone Disease ◽  
Diagnosis And Prognosis
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