Alcohol Abuse in Adolescents: Relevance of Animal Models and Experimental Results in Adolescent Animals

2015 ◽  
pp. 101-112
Author(s):  
Rosana Camarini ◽  
Ricardo M. Pautassi
Keyword(s):  
Animal Models ◽  
Alcohol Abuse ◽  
Experimental Results

scholarly journals Animal models for medications development targeting alcohol abuse using selectively bred rat lines: Neurobiological and pharmacological validity

2012 ◽  
Vol 103 (1) ◽  
pp. 119-155 ◽  
Author(s):  
Richard L. Bell ◽  
Helen J.K. Sable ◽  
Giancarlo Colombo ◽  
Petri Hyytia ◽  
Zachary A. Rodd ◽  
...  
Keyword(s):  
Animal Models ◽  
Alcohol Abuse

scholarly journals Independent validation of experimental results requires timely and unrestricted access to animal models and reagents

PLoS Genetics ◽  
2020 ◽  
Vol 16 (6) ◽  
pp. e1008940 ◽  
Author(s):  
Cassandra R. Diegel ◽  
Steven Hann ◽  
Ugur M. Ayturk ◽  
Jennifer C. W. Hu ◽  
Kyung-Eun Lim ◽  
...  
Keyword(s):  
Animal Models ◽  
Experimental Results ◽  
Independent Validation ◽  
Unrestricted Access

scholarly journals Right Ventricular-Pulmonary Vascular Interactions

Physiology ◽  
2017 ◽  
Vol 32 (5) ◽  
pp. 346-356 ◽  
Author(s):  
Diana M. Tabima ◽  
Jennifer L. Philip ◽  
Naomi C. Chesler
Keyword(s):  
Clinical Trials ◽  
Animal Models ◽  
Right Ventricular ◽  
Comprehensive Evaluation ◽  
Small Animal ◽  
Experimental Results ◽  
Cardiopulmonary Function ◽  
Volume Analysis ◽  
Future Studies ◽  
Small Animal Models

Accurate and comprehensive evaluation of right ventricular (RV)-pulmonary vascular (PV) interactions is critical to the assessment of cardiopulmonary function, dysfunction, and failure. Here, we review methods of quantifying RV-PV interactions and experimental results from clinical trials as well as large- and small-animal models based on pressure-volume analysis. We conclude by outlining critical gaps in knowledge that should drive future studies.

Reductionist thinking and animal models in neuropsychiatric research

2019 ◽  
Vol 42 ◽  
Author(s):  
Nicole M. Baran
Keyword(s):  
Animal Models ◽  
Mental Disorders ◽  
Environmental Factors ◽  
Neuropsychiatric Disorders ◽  
Model Organisms ◽  
Developmental Genetic ◽  
Term Study ◽  
Genetic And Environmental Factors ◽  
Mechanisms Of Plasticity

AbstractReductionist thinking in neuroscience is manifest in the widespread use of animal models of neuropsychiatric disorders. Broader investigations of diverse behaviors in non-model organisms and longer-term study of the mechanisms of plasticity will yield fundamental insights into the neurobiological, developmental, genetic, and environmental factors contributing to the “massively multifactorial system networks” which go awry in mental disorders.

Diagnostics of Gold Laser Plasmas

1988 ◽  
Vol 102 ◽  
pp. 357-360
Author(s):  
J.C. Gauthier ◽  
J.P. Geindre ◽  
P. Monier ◽  
C. Chenais-Popovics ◽  
N. Tragin ◽  
...  
Keyword(s):  
Experimental Results ◽  
Pure Gold ◽  
Electronic Temperature ◽  
X Ray ◽  
Laser Plasmas ◽  
Collisional Radiative Model ◽  
Radiative Model

AbstractIn order to achieve a nickel-like X ray laser scheme we need a tool to determine the parameters which characterise the high-Z plasma. The aim of this work is to study gold laser plasmas and to compare experimental results to a collisional-radiative model which describes nickel-like ions. The electronic temperature and density are measured by the emission of an aluminium tracer. They are compared to the predictions of the nickel-like model for pure gold. The results show that the density and temperature can be estimated in a pure gold plasma.

Observation of Phase Contrast Images in STEM and CTEM Modes by Using 100 kV Field Emission Electron Gun

1974 ◽  
Vol 32 ◽  
pp. 390-391
Author(s):  
Y. Harada ◽  
T. Goto ◽  
H. Koike ◽  
T. Someya
Keyword(s):  
Field Emission ◽  
Phase Contrast ◽  
Image Formation ◽  
Fresnel Diffraction ◽  
Experimental Results ◽  
Electron Gun ◽  
Scanning Microscopy ◽  
Emission Electron ◽  
Lattice Images

Since phase contrasts of STEM images, that is, Fresnel diffraction fringes or lattice images, manifest themselves in field emission scanning microscopy, the mechanism for image formation in the STEM mode has been investigated and compared with that in CTEM mode, resulting in the theory of reciprocity. It reveals that contrast in STEM images exhibits the same properties as contrast in CTEM images. However, it appears that the validity of the reciprocity theory, especially on the details of phase contrast, has not yet been fully proven by the experiments. In this work, we shall investigate the phase contrast images obtained in both the STEM and CTEM modes of a field emission microscope (100kV), and evaluate the validity of the reciprocity theory by comparing the experimental results.

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