The oxidative stress response system

2004 ◽  
pp. 59-76 ◽  
Author(s):  
André Korsloot ◽  
Cornelis A.M. van Gestel ◽  
Nico M. van Straalen
Keyword(s):  
Oxidative Stress ◽  
Stress Response ◽  
Oxidative Stress Response ◽  
Response System ◽  
Stress Response System

The Evolutionary Life History Model of Externalizing Personality: Bridging Human and Animal Personality Science to Connect Ultimate and Proximate Mechanisms Underlying Aggressive Dominance, Hostility, and Impulsive Sensation Seeking

2017 ◽  
Vol 21 (4) ◽  
pp. 330-353 ◽  
Author(s):  
Michael P. Hengartner
Keyword(s):  
Life History ◽  
Stress Response ◽  
Sensation Seeking ◽  
Inclusive Fitness ◽  
Interpersonal Behavior ◽  
Life History Strategies ◽  
Proximate Mechanisms ◽  
Response System ◽  
Trade Offs ◽  
Stress Response System

The present work proposes an evolutionary model of externalizing personality that defines variation in this broad psychobiological phenotype resulting from genetic influences and a conditional adaptation to high-risk environments with high extrinsic morbidity-mortality. Due to shared selection pressure, externalizing personality is coadapted to fast life history strategies and maximizes inclusive fitness under adverse environmental conditions by governing the major trade-offs between reproductive versus somatic functions, current versus future reproduction, and mating versus parenting efforts. According to this model, externalizing personality is a regulatory device at the interface between the individual and its environment that is mediated by 2 overlapping psychobiological systems, that is, the attachment and the stress-response system. The attachment system coordinates interpersonal behavior and intimacy in close relationships and the stress-response system regulates the responsivity to environmental challenge and both physiological and behavioral reactions to stress. These proximate mechanisms allow for the integration of neuroendocrinological processes underlying interindividual differences in externalizing personality. Hereinafter I further discuss the model's major implications for personality psychology, psychiatry, and public health policy.

scholarly journals Explaining inconsistent results in cancer quality of life studies: the role of the stress–response system

2008 ◽  
Vol 17 (2) ◽  
pp. 174-181 ◽  
Author(s):  
Harry van de Wiel ◽  
Erwin Geerts ◽  
Josette Hoekstra-Weebers
Keyword(s):  
Quality Of Life ◽  
Stress Response ◽  
Response System ◽  
Stress Response System

scholarly journals The Cpx Stress Response System Potentiates the Fitness and Virulence of Uropathogenic Escherichia coli

2013 ◽  
Vol 81 (5) ◽  
pp. 1450-1459 ◽  
Author(s):  
Irina Debnath ◽  
J. Paul Norton ◽  
Amelia E. Barber ◽  
Elizabeth M. Ott ◽  
Bijaya K. Dhakal ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Stress Response ◽  
Aminoglycoside Antibiotic ◽  
Deletion Mutants ◽  
Content Type ◽  
Response System ◽  
Stress Response System ◽  
Tract Infections ◽  
Auxiliary Factor

ABSTRACTStrains of uropathogenicEscherichia coli(UPEC) are the primary cause of urinary tract infections, representing one of the most widespread and successful groups of pathogens on the planet. To colonize and persist within the urinary tract, UPEC must be able to sense and respond appropriately to environmental stresses, many of which can compromise the bacterial envelope. The Cpx two-component envelope stress response system is comprised of the inner membrane histidine kinase CpxA, the cytosolic response regulator CpxR, and the periplasmic auxiliary factor CpxP. Here, by using deletion mutants along with mouse and zebrafish infection models, we show that the Cpx system is critical to the fitness and virulence of two reference UPEC strains, the cystitis isolate UTI89 and the urosepsis isolate CFT073. Specifically, deletion of thecpxRAoperon impaired the ability of UTI89 to colonize the murine bladder and greatly reduced the virulence of CFT073 during both systemic and localized infections within zebrafish embryos. These defects coincided with diminished host cell invasion by UTI89 and increased sensitivity of both strains to complement-mediated killing and the aminoglycoside antibiotic amikacin. Results obtained with thecpxPdeletion mutants were more complicated, indicating variable strain-dependent and niche-specific requirements for this well-conserved auxiliary factor.

Cutaneous Expression of CRH and CRH-R: Is There a “Skin Stress Response System?”

2006 ◽  
Vol 885 (1) ◽  
pp. 287-311 ◽  
Author(s):  
ANDRZEJ T. SLOMINSKI ◽  
VLADIMIR BOTCHKAREV ◽  
MASHKOOR CHOUDHRY ◽  
NADEEM FAZAL ◽  
KLAUS FECHNER ◽  
...  
Keyword(s):  
Stress Response ◽  
Response System ◽  
Stress Response System

Investigation of the Endogenous Stress Response System in Patients with Chronic Schizophrenia

2015 ◽  
Vol 72 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Alessio Maria Monteleone ◽  
Palmiero Monteleone ◽  
Carmela Di Filippo ◽  
Francesca Pellegrino ◽  
Francesco Grillo ◽  
...  
Keyword(s):  
Stress Response ◽  
Chronic Schizophrenia ◽  
Response System ◽  
Stress Response System
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