Impact of Excipient Interactions on Drug Bioavailability from Solid Dosage Forms

2015 ◽  
pp. 273-310 ◽  
Author(s):  
Ravikiran Panakanti ◽  
Ajit S. Narang
Keyword(s):  
Dosage Forms ◽  
Drug Bioavailability ◽  
Solid Dosage Forms ◽  
Solid Dosage ◽  
Excipient Interactions

Recent Strategic Developments in the Use of Superdisintegrants for Drug Delivery

2020 ◽  
Vol 26 (6) ◽  
pp. 701-709
Author(s):  
Phuong H.L. Tran ◽  
Thao T.D. Tran
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Controlled Drug Release ◽  
Dosage Forms ◽  
Delivery Systems ◽  
Therapeutic Effects ◽  
Drug Bioavailability ◽  
Solid Dosage Forms ◽  
Solid Dosage ◽  
Innovative Materials

Improving drug bioavailability in the pharmaceutical field is a challenge that has attracted substantial interest worldwide. The controlled release of a drug can be achieved with a variety of strategies and novel materials in the field. In addition to the vast development of innovative materials for improving therapeutic effects and reducing side effects, the exploration of remarkable existing materials could encourage the discovery of diverse approaches for adapted drug delivery systems. Recently, superdisintegrants have been proposed for drug delivery systems as alternative approaches to maximize the efficiency of therapy. Although superdisintegrants are well known and used in solid dosage forms, studies on strategies for the development of drug delivery systems using superdisintegrants are lacking. Therefore, this study reviews the use of superdisintegrants in controlled drug release dosage formulations. This overview of superdisintegrants covers developed strategies, types (including synthetic and natural materials), dosage forms and techniques and will help to improve drug delivery systems.

Extrusion-based 3D printing of oral solid dosage forms: Material requirements and equipment dependencies

2021 ◽  
Vol 598 ◽  
pp. 120361 ◽  
Author(s):  
S. Henry ◽  
A. Samaro ◽  
F.H. Marchesini ◽  
B. Shaqour ◽  
J. Macedo ◽  
...  
Keyword(s):  
3D Printing ◽  
Dosage Forms ◽  
Solid Dosage Forms ◽  
Solid Dosage ◽  
Material Requirements
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