Recent Advances in Numerical Analysis of Nonlinear Vibrations of Complex Structures with Friction Contact Interfaces

Recent Advances in the Chemical Biology of N-Glycans

Molecules ◽

10.3390/molecules26041040 ◽

2021 ◽

Vol 26 (4) ◽

pp. 1040

Author(s):

Asuka Shirakawa ◽

Yoshiyuki Manabe ◽

Koichi Fukase

Keyword(s):

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Molecular Basis ◽

Chemical Biology ◽

Molecular Level ◽

Chemoenzymatic Synthesis ◽

Complex Structures ◽

Recent Advances ◽

Protein Functions ◽

Potential Applications

Asparagine-linked N-glycans on proteins have diverse structures, and their functions vary according to their structures. In recent years, it has become possible to obtain high quantities of N-glycans via isolation and chemical/enzymatic/chemoenzymatic synthesis. This has allowed for progress in the elucidation of N-glycan functions at the molecular level. Interaction analyses with lectins by glycan arrays or nuclear magnetic resonance (NMR) using various N-glycans have revealed the molecular basis for the recognition of complex structures of N-glycans. Preparation of proteins modified with homogeneous N-glycans revealed the influence of N-glycan modifications on protein functions. Furthermore, N-glycans have potential applications in drug development. This review discusses recent advances in the chemical biology of N-glycans.

Download Full-text

Recent Advances in Numerical Analysis.

Mathematics of Computation ◽

10.2307/2007307 ◽

1982 ◽

Vol 38 (158) ◽

pp. 654

Author(s):

Carl de Boor ◽

Gene H. Golub

Keyword(s):

Numerical Analysis ◽

Recent Advances

Download Full-text

Tube Bending Forming Technologies: Advances and Trends

Encyclopedia of Aluminum and Its Alloys ◽

10.1201/9781351045636-140000210 ◽

2019 ◽

Author(s):

Li Heng ◽

Yang He ◽

Ma Jun

Keyword(s):

Health Care ◽

High Performance ◽

Optimization Design ◽

High Efficiency ◽

Complex Structures ◽

Tube Bending ◽

Multiple Defects ◽

Recent Advances ◽

Key Technologies

Bent tube parts have been widely used, as one kind of key components with enormous quantities and diversities, to satisfy the increasing demands for lightweight and high-performance products in broad industries such as aerospace, marine, automobile, energy, and health care. Tube bending is one of the key technologies used for manufacturing these lightweight products. The recent advances in tube bending are critically reviewed from four fundamental issues in tube bending, viz. characterization of tubular materials, prediction of multiple defects, bending formability, and innovative optimization design. Advantages and limitations of some recently developed innovative bending approaches are reviewed. Finally, considering the urgent requirements of more lightweight and high-performance bent tubes with hard-to-deform materials with complex structures, the development trends and corresponding challenges are thereafter presented for realizing the precision and high-efficiency tube bending.

Download Full-text