Optimization of Radial Dose Function for Varian Ir-192 Brachytherapy Source Model VS2000

Author(s):  
A. M. Outif ◽  
A. A. Elawadi
2022 ◽  
Vol 30 (1) ◽  
pp. 691-708
Author(s):  
Nor Shazleen Ab Shukor ◽  
Marianie Musarudin ◽  
Reduan Abdullah ◽  
Mohd Zahri Abdul Aziz

This study aims to measure the radial dose function and anisotropy function F(r, θ) of high Dose Rate (HDR) 192Ir source in a fabricated water-equivalent phantom using Gafchromic® EBT3 film and TLD-100H and to compare the results obtained with the MCNP5 calculated values. The phantom was fabricated using Perspex PMMA material. For, the EBT3 films with a required dimension and TLD-100H chips were placed at r=1, 2, 3, 5, and 10 cm from the source. The F(r, θ) measurements were carried out at r=1, 2, 3, 5, and 10 cm with the angle range from 10° to 170°. The result of from EBT3 film and TLD-100H was in good agreement (2.10%±1.99). Compared to MCNP5, the differences are within 0.31% to 11.47% for EBT3 film and 0.08% to 10.58% for TLD-100H. For the F(r, θ), an average deviation with the MCNP5 calculation is 4.94%±2.7. For both and F(r, θ), the effects are prominent at r=10 cm. At this distance, the response of both Gafchromic® EBT3 film and TLD-100H shows less sensitivity as the dose followed the inverse square law. This work demonstrates that Gafchromic® EBT3 film dosimeter and TLD-100H are suitable dosimeters in 192Ir dosimetric measurements at a radial distance of ˂5 cm


2019 ◽  
Vol 25 (1) ◽  
pp. 15-22 ◽  
Author(s):  
Zeinab Fardi ◽  
Payvand Taherparvar

Abstract Permanent and temporary implantation of I-125 brachytherapy sources has become an official method for the treatment of different cancers. In this technique, it is essential to determine dose distribution around the brachytherapy source to choose the optimal treatment plan. In this study, the dosimetric parameters for a new interstitial brachytherapy source I-125 (IrSeed-125) were calculated with GATE/GEANT4 Monte Carlo code. Dose rate constant, radial dose function and 2D anisotropy function were calculated inside a water phantom (based on the recommendations of TG-43U1 protocol), and inside several tissue phantoms around the IrSeed-125 capsule. Acquired results were compared with MCNP simulation and experimental data. The dose rate constant of IrSeed-125 in the water phantom was about 1.038 cGy·h−1U−1 that shows good consistency with the experimental data. The radial dose function at 0.5, 0.9, 1.8, 3 and 7 cm radial distances were obtained as 1.095, 1.019, 0.826, 0.605, and 0.188, respectively. The results of the IrSeed-125 is not only in good agreement with those calculated by other simulation with MCNP code but also are closer to the experimental results. Discrepancies in the estimation of dose around IrSeed-125 capsule in the muscle and fat tissue phantoms are greater than the breast and lung phantoms in comparison with the water phantom. Results show that GATE/GEANT4 Monte Carlo code produces accurate results for dosimetric parameters of the IrSeed-125 LDR brachytherapy source with choosing the appropriate physics list. There are some differences in the dose calculation in the tissue phantoms in comparison with water phantom, especially in long distances from the source center, which may cause errors in the estimation of dose around brachytherapy sources that are not taken account by the TG43-U1 formalism.


2005 ◽  
Vol 50 (6) ◽  
pp. 1109-1117 ◽  
Author(s):  
Carmen S Guzmán Calcina ◽  
Adelaide de Almeida ◽  
José R Oliveira Rocha ◽  
Felipe Chen Abrego ◽  
Oswaldo Baffa

Author(s):  
Ning J. Yue ◽  
Kent Lambert ◽  
Jay E. Reiff ◽  
Anthony E. Dragun ◽  
Ning J. Yue ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-11
Author(s):  
C. H. Wu ◽  
Y. J. Liao ◽  
Y. W. Hsueh Liu ◽  
S. K. Hung ◽  
M. S. Lee ◽  
...  

This study used MCNPX code to investigate the brachytherapy192Ir dose distributions in water, bone, and lung tissue and performed radiophotoluminescent glass dosimeter measurements to verify the obtained MCNPX results. The results showed that the dose-rate constant, radial dose function, and anisotropy function in water were highly consistent with data in the literature. However, the lung dose near the source would be overestimated by up to 12%, if the lung tissue is assumed to be water, and, hence, if a tumor is located in the lung, the tumor dose will be overestimated, if the material density is not taken into consideration. In contrast, the lung dose far from the source would be underestimated by up to 30%. Radial dose functions were found to depend not only on the phantom size but also on the material density. The phantom size affects the radial dose function in bone more than those in the other tissues. On the other hand, the anisotropy function in lung tissue was not dependent on the radial distance. Our simulation results could represent valid clinical reference data and be used to improve the accuracy of the doses delivered during brachytherapy applied to patients with lung cancer.


Sign in / Sign up

Export Citation Format

Share Document