Selecting Regions of Interest in SPECT Images Using Wilcoxon Test for the Diagnosis of Alzheimer’s Disease

2010 ◽  
pp. 446-451 ◽  
Author(s):  
D. Salas-Gonzalez ◽  
J. M. Górriz ◽  
J. Ramírez ◽  
F. Segovia ◽  
R. Chaves ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Regions Of Interest ◽  
Wilcoxon Test ◽  
Spect Images

scholarly journals Prospective and retrospective memory in mild Alzheimer's disease

2008 ◽  
Vol 66 (2b) ◽  
pp. 318-322 ◽  
Author(s):  
Sergilaine Pereira Martins ◽  
Benito Pereira Damasceno
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Prospective Memory ◽  
Verbal Learning ◽  
Wilcoxon Test ◽  
Retrospective Memory ◽  
Memory Tests ◽  
Memory And Attention ◽  
Auditory Verbal Learning ◽  
Learning Test

OBJECTIVE: To study prospective and retrospective memory in patients with mild Alzheimer's disease (AD). METHOD: Twenty mild AD and 20 matched normal control subjects were included. Diagnosis of AD was based on DSM-IV and NINCDS-ADRDA criteria, using CDR 1 and MMSE scores from 16 to 24 for mild AD. All subjects underwent retrospective (Rey Auditory Verbal Learning Test, RAVLT) and prospective memory tests (the appointment and belonging subtests of the Rivermead Behavioral Memory Test, RBMT; and two tests made to this study: the clock and the animals test), as well as MMSE, neuropsychological counterproofs, and Cornell Scale for Depression in Dementia. The data was analyzed with Wilcoxon test and Spearman correlation coefficient. RESULTS: AD patients performed worse than controls in prospective and retrospective memory tests, with poorer performance in retrospective memory. There was no correlation between prospective memory and attention, visual perception, executive function, or depression scores. CONCLUSION: Prospective and, in higher degree, retrospective memory are primarily and independently impaired in mild AD.

5-12-05 “Reversed triangle” pattern on 3D SPECT images is characteristic of Alzheimer's disease

1997 ◽  
Vol 150 ◽  
pp. S293
Author(s):  
Takahiro Sasaki ◽  
Yasuo Fukuuchi ◽  
Takahiro Amano ◽  
Kazuhiro Muramatsu ◽  
Yoshiaki Itoh ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Spect Images

P2-425: PIB-PET images, compared with MR, FDG-PET, and IMP-SPECT images, of a patient with Alzheimer's disease with presenilin-1 mutation (Met233Leu) showing a new phenotype

2010 ◽  
Vol 6 ◽  
pp. S443-S444
Author(s):  
Masahiko Takaya ◽  
Toshihisa Tanaka ◽  
Suzuka Ataka ◽  
Hiroyuki Shimada ◽  
Takashi Morihara ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Fdg Pet ◽  
Presenilin 1 ◽  
Presenilin 1 Mutation ◽  
Spect Images

scholarly journals Neuropsychiatric Symptoms in Behavioral Variant Frontotemporal Dementia and Alzheimer's Disease: A 12-Month Follow-Up Study

2021 ◽  
Vol 12 ◽  
Author(s):  
Thais Bento Lima Da Silva ◽  
Tiago Nascimento Ordonez ◽  
Allan Gustavo Bregola ◽  
Valéria Santoro Bahia ◽  
Mário Amore Cecchini ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Frontotemporal Dementia ◽  
Neuropsychiatric Symptoms ◽  
Linear Regression Analysis ◽  
Predictor Variable ◽  
Wilcoxon Test ◽  
Chi Square ◽  
Behavioral Variant Frontotemporal Dementia

Introduction: Neuropsychiatric symptoms in patients with frontotemporal dementia (FTD) are highly prevalent and may complicate clinical managements.Objective: To test whether the Neuropsychiatry Inventory (NPI) could detect change in neuropsychiatric symptoms and caregiver's distress in patients diagnosed with behavioral variant frontotemporal dementia (bvFTD) and Alzheimer's disease (AD) from baseline to a 12-month follow-up and to investigate possible predictors of change in NPI scores.Methods: The sample consisted of 31 patients diagnosed with bvFTD and 28 patients with AD and their caregivers. The Mini-Mental State Examination (MMSE), Addenbrooke's Cognitive Examination Revised (ACE-R), the INECO Frontal Screening (IFS), the Frontal Assessment Battery (FAB), the Executive Interview (EXIT-25) and the NPI were applied. Descriptive statistics, Mann-Whitney U test, Wilcoxon test, Chi square (χ2) test and Linear Regression Analysis were used.Results: NPI total and caregiver distress scores were statistically higher among bvFTD patients at both assessment points. MMSE, ACE-R scores significantly declined and NPI Total and Distress scores significantly increased in both groups. In the bvFTD group, age was the only independent predictor variable for the NPI total score at follow up. In the AD group, ACE-R and EXIT-25, conjunctively, were associated with the NPI total score at follow up.Conclusions: In 12 months, cognition declined and neuropsychiatric symptoms increased in bvFTD and AD groups. In the AD group only, cognitive impairment was a significant predictor of change in neuropsychiatric symptoms.

Differential automatic diagnosis between Alzheimer's disease and frontotemporal dementia based on perfusion SPECT images

2009 ◽  
Vol 47 (2) ◽  
pp. 147-158 ◽  
Author(s):  
Jean-François Horn ◽  
Marie-Odile Habert ◽  
Aurélie Kas ◽  
Zoulikha Malek ◽  
Philippe Maksud ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Frontotemporal Dementia ◽  
Automatic Diagnosis ◽  
Perfusion Spect ◽  
Spect Images

Statistical Parametric Mapping of 99mTc-HMPAO-SPECT Images for the Diagnosis of Alzheimer's Disease: Normalizing to Cerebellar Tracer Uptake

NeuroImage ◽  
2002 ◽  
Vol 17 (3) ◽  
pp. 1193-1202 ◽  
Author(s):  
Darius Soonawala ◽  
Tania Amin ◽  
Klaus P. Ebmeier ◽  
J.Douglas Steele ◽  
Nadine J. Dougall ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Statistical Parametric Mapping ◽  
Tracer Uptake ◽  
Parametric Mapping ◽  
Hmpao Spect ◽  
99Mtc Hmpao ◽  
Spect Images
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