Medical Management of Chronic Rhinosinusitis

Author(s):  
Thunchai Thanasumpun ◽  
Pete S. Batra
2021 ◽  
pp. 019459982110069
Author(s):  
Lauren E. Miller ◽  
Neil Bhattacharyya

Chronic rhinosinusitis (CRS) management frequently comprises conservative treatment, including a combination of topical and oral corticosteroids (OCSs). However, in the midst of the coronavirus disease 2019 (COVID-19) pandemic, providers may have been reluctant to prescribe OCSs out of possible concern for an increased risk of contracting COVID-19 or developing more severe COVID-19 symptoms. This study thus sought to explore the association between the use of OCSs and the development of COVID-19 in patients with CRS. We found no statistically significant difference in the rates of patients with a positive diagnosis of COVID-19 who underwent an OCS treatment regimen compared to those who did not, both within 28 days ( P = .389) and 14 days ( P = .676) prior to the COVID-19 test. Given OCSs are often a major component of medical management of CRS, this study proves helpful in counseling patients on risks of steroid use in CRS treatment during the COVID-19 pandemic.


2020 ◽  
pp. 014556131987690
Author(s):  
Ahmed Mansi ◽  
Roger Bui ◽  
Mohamad R. Chaaban

Background: Oral corticosteroids are often used in the medical management of chronic rhinosinusitis (CRS) with and without polyps. The purpose of our study is to review the literature for studies reporting the dosage of oral corticosteroids as part of the appropriate medical management prior to, immediately before, and after surgical intervention. Methods: We reviewed the literature for oral corticosteroid regimens given to patients with CRS from March 2012 to September 2018. Studies that did not disclose the exact doses of the regimen were excluded from our analysis. Results: Our search resulted in 7 articles with 4 studies of Level of Evidence (LOE) 1b, 2 studies with LOE III, and 1 study with LOE IV. The daily doses varied from 15 mg to 1 mg/kg, and with total doses ranging from 150 to 352 mg. In addition, several studies gave the same regimen to both subtypes of CRS. There was no mention of side effects in most of the studies. Conclusion: There is a wide variation in the steroid doses given to patients with CRS and prospective or randomized controlled trials are needed to provide better improved evidence.


2008 ◽  
Vol 100 (6) ◽  
pp. 529-532 ◽  
Author(s):  
Edward W. Skorpinski ◽  
Patrick M. Vannelli ◽  
Ejaz Yousef ◽  
Timothy Brunell ◽  
Stephen J. McGeady

2015 ◽  
Vol 5 (11) ◽  
pp. 1018-1027 ◽  
Author(s):  
Lauren J. Luk ◽  
Toby O. Steele ◽  
Jess C. Mace ◽  
Zachary M. Soler ◽  
Luke Rudmik ◽  
...  

2019 ◽  
Vol 7 (2) ◽  
pp. 32 ◽  
Author(s):  
Chetan Safi ◽  
Zhong Zheng ◽  
Emily Dimango ◽  
Claire Keating ◽  
David Gudis

Chronic rhinosinusitis (CRS) is nearly ubiquitous in patients with cystic fibrosis (CF). CF CRS is a challenging entity to define, diagnose, and treat, as patients often have severe refractory sinus disease in addition to complex medical comorbidities. The purpose of this article is to review the literature on the medical management of CF CRS and determine how to best identify, diagnose, and manage CF CRS. Ultimately, the treatment of these patients requires a multi-disciplinary approach involving the pulmonologist and otolaryngologist.


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