Computer Aided Protein Design: Three Dimensional Model Building of the Saruplase Structure

1991 ◽  
pp. 159-166
Author(s):  
W. Straßburger ◽  
W. Winter ◽  
G. J. Steffens ◽  
W. A. Günzler ◽  
L. Flohé
2017 ◽  
Vol 903 ◽  
pp. 120-127 ◽  
Author(s):  
Elena María Beamud González ◽  
Pedro Jose Núñez López ◽  
Eustaquio García Plaza ◽  
David Rodríguez Salgado ◽  
Alfonso González González ◽  
...  

One of the main shortcomings of individualized training in the use of computer aided design (CAD), and computer aided manufacturing (CAM) tools is that students lack a sound and broad understanding of the type of tools, and their specific and integrated applications in industrial manufacturing. This study aimed to design an integrated curricular training programme in computer aided tools for the design and manufacture of mechanical components based on reverse engineering techniques. By using real products that students can see and touch, a scanned copy is obtained for subsequent reconstruction into a virtual three-dimensional model using the software for optimizing the point cloud, meshing, and creating both the surface and solid. Once the virtual three-dimensional model has been obtained, it is exported to a solid modelling CAD (3D-CAD) software for modification according to the geometrical requirements. The next step is for students to manufacture a component using rapid prototyping techniques, which allow them to visualize, analyse, and inspect a component to optimize its design. The use of computer aided manufacturing software enables students to design and plan machining operations virtually to obtain a computer numeric control (CNC) program for the manufacture of a component with a CNC machine tool. Finally, students perform a quality control of the component by employing a range of measurement techniques. This training program is integrated into the subjects of the mechanical engineering degree, where students can work with these tools in line with an intergraded curriculum.


Author(s):  
Kadir Gok

Viruses spreads very quickly and has a fatal risk in people with chronic disease. As the virus vaccine and medications to be used for treatment are not fully developed, alternative ways to protect it from the virus are being investigated. In this study, the effects of a classical face mask on human face were investigated and computer-aided analyses were performed. Three-dimensional model of the classical face mask was performed with the SolidWorks software. The analyses were performed using AnsysWorkbench Static Structural module. The load, boundary conditions and material were defined in the AnsysWorkbench. As a result of the analyses, it has been determined that classical masks influence human face. The classical masks have a negative effective in terms of irritation on the human face. The occurred stresses cause irritation on one's skin. The use of silicone pads has been shown to reduce these effects. It was proved by this study that silicon pads can be used as an alternative method to reduce these stresses. In the future, it is planned to conduct studies investigating mask materials that do not irritate the human face.


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