Alterations of Receptors and of Agonist Effectiveness in Myocardial Failure

1988 ◽  
pp. 441-448 ◽  
Author(s):  
E. Erdmann ◽  
M. Böhm
Keyword(s):  
Myocardial Failure

Diagnosis of coronary affection in patients with AADA and treatment of postcardiotomy myocardial failure using extracorporeal life support (ECLS)

2014 ◽  
Vol 17 (5) ◽  
pp. 253 ◽  
Author(s):  
Sabina P W Guenther ◽  
Sven Peterss ◽  
Angela Reichelt ◽  
Frank Born ◽  
Matthias Fischer ◽  
...  
Keyword(s):  
Heart Failure ◽  
Coronary Artery ◽  
Life Support ◽  
Extracorporeal Life Support ◽  
Artery Bypass ◽  
Preoperative Evaluation ◽  
Left Heart Failure ◽  
Myocardial Failure ◽  
Coronary Abnormalities ◽  
Ventricular Support

<p><b>Background:</b> Myocardial ischemia due to concomitant coronary artery disease (CAD) or coronary dissection in patients with acute aortic dissection type Stanford A (AADA) is associated with myocardial failure and poor outcomes. Preoperative coronary angiography in this group of patients is still debated. The use of CT scan to diagnose coronary affection along with the establishment of high-pitched dual-spiral CT protocols are essential for improving outcomes.</p><p><b>Methods:</b> We retrospectively analyzed six AADA patients with heart failure who were treated using extracorporeal life support (ECLS). Options for diagnosing coronary affection and different therapeutic strategies for postcardiotomy cardiogenic shock in this patient cohort are discussed.</p><p><b>Results:</b> Retrospective review of CT images showed coronary abnormalities in 83% (n = 5). Four patients (67%) underwent unplanned coronary artery bypass grafting (CABG). ECLS was instituted in 67% (n = 4) due to left heart failure and in 33% (n = 2) due to right heart failure. Thirty day mortality was 67% (n = 4). The two patients that received ECLS for right ventricular support survived and both had undergone CABG.</p><p><b>Conclusion:</b> Besides preoperative evaluation of the extent of the dissection, focus on coronary affection in CT-scans helps to triage the operative procedure. Hybrid operating rooms allow for immediate interventional and/or surgical treatment and enable for immediate control of revascularization results. The use of ECLS over other types of ventricular support systems may allow for myocardial recovery in selected cases.</p>

Pathologic Hypertrophy with Fibrosis: The Structural Basis for Myocardial Failure

1992 ◽  
Vol 1 (2) ◽  
pp. 75-85 ◽  
Author(s):  
Karl T. Weber ◽  
Christian G. Brilla ◽  
Scott E. Campbell ◽  
Guoping Zhou ◽  
Luiz Matsubara ◽  
...  
Keyword(s):  
Structural Basis ◽  
Myocardial Failure

Role of Endothelin-1 in Myocardial Failure

1999 ◽  
Vol 111 (5) ◽  
pp. 417-422 ◽  
Author(s):  
Flora Sam ◽  
Wilson S. Colucci
Keyword(s):  
Endothelin 1 ◽  
Myocardial Failure

ISOPRENALINE IN MYOCARDIAL FAILURE

The Lancet ◽  
1965 ◽  
Vol 286 (7409) ◽  
pp. 442-443 ◽  
Author(s):  
M.J. Greenberg
Keyword(s):  
Myocardial Failure

Successful treatment of severe myocardial failure after postpartum haemorrhage with the use of an intra-aortic balloon pump

1999 ◽  
Vol 25 (2) ◽  
pp. 223-225 ◽  
Author(s):  
A. Mayr ◽  
W. Lederer ◽  
M. Mörtl ◽  
J. Margreiter ◽  
M. Hoi ◽  
...  
Keyword(s):  
Successful Treatment ◽  
Postpartum Haemorrhage ◽  
Intra Aortic Balloon Pump ◽  
Myocardial Failure

RESUSCITATION AND TREATMENT FOLLOWING SUBMERSION

PEDIATRICS ◽  
1966 ◽  
Vol 37 (4) ◽  
pp. 666-668
Author(s):  
Joseph S. Redding
Keyword(s):  
Fresh Water ◽  
Positive Pressure Ventilation ◽  
Sea Water ◽  
Intermittent Positive Pressure Ventilation ◽  
Positive Pressure ◽  
Cardiac Massage ◽  
Closed Chest ◽  
Myocardial Failure ◽  
Exhaled Air ◽  
Electrical Defibrillation

In resuscitation from drowning it must be remembered that when breathing movements are absent no time must be wasted in attempts to drain the lungs. Reoxygenation must be started immediately with exhaled air. Positive pressure ventilation with oxygen should be substituted as soon as possible. It should be continued in victims of sea water submersion until a blood specimen can be examined and any plasma deficiency corrected. In fresh water drowning intermittent positive pressure ventilation combined with closed chest cardiac massage is a preliminary to external electrical defibrillation. Prevention of delayed death depends upon the management of massive hemolysis, hypervolemia, electrolyte imbalances, aspiration pneumonitis, and myocardial failure.

Cardiorespiratory Status of Erythroblastotic Newborn Infants: III. Intravascular Pressures During the First Hours of Life

PEDIATRICS ◽  
1976 ◽  
Vol 58 (4) ◽  
pp. 484-493
Author(s):  
Roderic H. Phibbs ◽  
Paul Johnson ◽  
Joseph A. Kitterman ◽  
George A. Gregory ◽  
William H. Tooley ◽  
...  
Keyword(s):  
Central Venous Pressure ◽  
Blood Volume ◽  
High Pressures ◽  
Venous Pressure ◽  
Newborn Infants ◽  
Hydrops Fetalis ◽  
Central Venous ◽  
Myocardial Failure ◽  
Prematurely Born Infants

We measured aortic and central venous pressures beginning soon after birth in 40 prematurely born infants with moderate or severe erythroblastosis fetalis, including 13 with severe and 10 with mild hydrops fetalis. All but four were asphyxiated at birth and this affected intravascular pressures. Before resuscitation, aortic or central venous pressure or both were elevated in more than one third. All but two of the remaining infants had normal initial pressures. Following resuscitation which relieved acidosis, hypoxia, and anemia, but did not reduce blood volume, the high pressures usually fell to normal and occasionally to subnormal levels, normal pressures fell to subnormal in almost one half, and those with initial subnormal pressures remained hypotensive. In all, 40% were hypotensive after resuscitation; treatment with blood volume expanders consistently returned these pressures to normal. Only two of the 13 severely hydropic infants and none of the mildly hydropic had findings indicative of hypervolemia and myocardial failure which persisted after treatment of asphyxia.

Cardiovascular functions in the dog rewarmed rapidly and slowly from deep hypothermia

1960 ◽  
Vol 198 (2) ◽  
pp. 333-335 ◽  
Author(s):  
H. E. D'Amato ◽  
Suzanne Kronheim ◽  
B. G. Covino
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Cardiac Output ◽  
Superior Vena ◽  
Vena Cava ◽  
Deep Hypothermia ◽  
Cardiovascular Collapse ◽  
Cardiovascular Failure ◽  
Myocardial Failure ◽  
Cardiovascular Functions

Heart rate, blood pressure, cardiac output and cardiac minute work were measured in pentobarbitalized dogs prior to induction of hypothermia, at rectal temperatures of 25°C or 20°C and following rapid rewarming in warm water or slow rewarming by wrapping in heated sheeting. During rapid rewarming from either 25°C or 20°C no consistent failure in recovery of normal cardiovascular function was observed, although 1 out of 10 dogs did suffer cardiovascular collapse during rapid rewarming. Slow rewarming from 25° and 20°C resulted in consistent failure of some or all of these functions to recover to prehypothermic levels. Moreover, 5 out of 15 slowly rewarmed dogs suffered cardiovascular collapse during the rewarming process. In five dogs slowly rewarmed from 20°C saline was infused into the superior vena cava. This procedure resulted in moderate increases in blood pressure but dramatic increases in cardiac output and minute work (200% and 270%, respectively), thereby negating myocardial failure as the primary cause of the occasionally observed cardiovascular failure.

scholarly journals Expression of a  -adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice

1998 ◽  
Vol 95 (12) ◽  
pp. 7000-7005 ◽  
Author(s):  
H. A. Rockman ◽  
K. R. Chien ◽  
D.-J. Choi ◽  
G. Iaccarino ◽  
J. J. Hunter ◽  
...  
Keyword(s):  
Adrenergic Receptor ◽  
Receptor Kinase ◽  
Myocardial Failure
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