Heat Shock Proteins and Immune Response

1991 ◽  
Keyword(s):  
Immune Response ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Shock Proteins

Heat shock proteins as regulators of the immune response

The Lancet ◽  
2003 ◽  
Vol 362 (9382) ◽  
pp. 469-476 ◽  
Author(s):  
A Graham Pockley
Keyword(s):  
Immune Response ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Shock Proteins

Enhancement of Th1 immune response by CD8α+ dendritic cells loaded with heat shock proteins enriched tumor extract in tumor-bearing mice

2009 ◽  
Vol 260 (1) ◽  
pp. 28-32 ◽  
Author(s):  
Abbas Azadmehr ◽  
Ali Akbar Pourfathollah ◽  
Zahra Amirghofran ◽  
Zuhair Mohammad Hassan ◽  
Seyed Mohammad Moazzeni
Keyword(s):  
Immune Response ◽  
Dendritic Cells ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Tumor Bearing ◽  
Tumor Extract ◽  
Shock Proteins ◽  
Th1 Immune Response

Detection of the host immune response to Burkholderia mallei heat-shock proteins GroEL and DnaK in a glanders patient and infected mice

2007 ◽  
Vol 59 (2) ◽  
pp. 137-147 ◽  
Author(s):  
Kei Amemiya ◽  
Jennifer L. Meyers ◽  
David DeShazer ◽  
Renaldo N. Riggins ◽  
Stephanie Halasohoris ◽  
...  
Keyword(s):  
Immune Response ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Host Immune Response ◽  
Burkholderia Mallei ◽  
Shock Proteins

scholarly journals Violation of antimitochondrial tolerance in patients with multiple repreduction failure

2019 ◽  
pp. 93-98
Author(s):  
B. V. Dons’koi ◽  
V. P. Chernyshov ◽  
K. S. Stepaniuk ◽  
K. J. Krychkov
Keyword(s):  
Immune Response ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Pregnant Women ◽  
Autoimmune Response ◽  
Implantation Failure ◽  
Repeated Implantation Failure ◽  
Shock Proteins ◽  
Antigen Structure ◽  
Specific Lipid

Mitochondria are semi-autonomic organelle that consist specific lipid and protein antigen structure. Evolutionary this structure is close to bacterial antigens (cardiolipin and heat shock proteins HSP). Immune response to pathogens can result to cross-reaction and development of proto-autoimmune and true autoimmune response in individuals with affected anti-mitochondrial tolerance. Serum from 127 healthy pregnant women (HPW), 58women with infertility (IF) and 149 patients with repeated implantation failure (RIF) (> 2) after IVF, was analyzed by ELISA for anti-Chlamidia IgG anti-HSP60 and cofactor-independent anti cardiolipin IgG (aCL). We show that in RIF patients aCL presence was significantly higher 23.9 % (34/142) than in HP women 7 % (9/127) and IF group 13.7 % (8/58). Anti-HSP60 ab was registered generally in RIF 8.6 % (11/98) while only one patient from IF group was anti-HSP60 positive 1.7 % (1/58) and any in HP group (0/127). We find the association between Anti-HSP60 and aCL ab. Patients with Anti-HSP60 ab was positive for aCL in 36.4 % (4/11) that was more frequently compared to both Anti-HSP60-negative: Chlamydia IgG positive 16.7 % (12/72) or Chlamydia IgG negative patients 10.9 % (33/302). We showed that aCL and Anti-HSP60 associated with repeated implantation failure and both reflect anti-mitochondrial tolerance dysfunction as hyper and hypo diagnostic markers.

Heat shock proteins and immune response: methods to madness

Methods ◽  
2004 ◽  
Vol 32 (1) ◽  
pp. 1-2 ◽  
Author(s):  
Pramod Srivastava
Keyword(s):  
Immune Response ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Shock Proteins
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