Comparison of Autogenous Cortical Graft and Demineralized Allogenic Bone Matrix (DABM) in the Fixation of Segmental Prosthesis

Limb Salvage ◽  
1991 ◽  
pp. 335-343
Author(s):  
B. W. Wippermann ◽  
R. W. W. Hsu ◽  
E. Y. S. Chao ◽  
F. H. Sim
Keyword(s):  
Bone Matrix ◽  
Allogenic Bone

Current Approaches of Bone Morphogenetic Proteins in Dentistry

2015 ◽  
Vol 41 (3) ◽  
pp. 337-342 ◽  
Author(s):  
Rosa-María Díaz-Sánchez ◽  
Rosa-María Yáñez-Vico ◽  
Ana Fernández-Olavarría ◽  
Regina Mosquera-Pérez ◽  
Alejandro Iglesias-Linares ◽  
...  
Keyword(s):  
Bone Morphogenetic Proteins ◽  
Specific Growth ◽  
Bone Matrix ◽  
Bone Lesions ◽  
Allogenic Bone ◽  
Bone Morphogenic Proteins ◽  
Alloplastic Materials ◽  
Bone Response ◽  
Near Future

Bone morphogenic proteins (BMPs) are a group of osteoinductive proteins obtained from nonmineralized bone matrix; they are capable of stimulating the differentiation of pluripotent mesenchymal cells to osteoprogenitor cells. They have become a likely treatment option, given their action on regeneration and remodeling of bone lesions and increasing the bone response around alloplastic materials. It may be feasible in the near future for BMPs to replace autologous and allogenic bone grafts. The application of specific growth factors for osteoinduction without using a bone graft constitutes a real impact on bone regeneration. The use of BMP is not only focused on osteogenic regeneration: There are a variety of studies investigating other properties, such as periodontal or dental regeneration from the conservative viewpoint. In this review, we will highlight the role of the BMP in bone, periodontal and dental regeneration.

Grafton Allogenic Bone Matrix

Neurosurgery ◽  
1994 ◽  
Vol 35 (2) ◽  
pp. 337-337
Author(s):  
Stephen T. Onesti
Keyword(s):  
Bone Matrix ◽  
Allogenic Bone

Grafton Allogenic Bone Matrix

Neurosurgery ◽  
1994 ◽  
Vol 35 (2) ◽  
pp. 337
Author(s):  
Stephen T. Onesti
Keyword(s):  
Bone Matrix ◽  
Allogenic Bone

scholarly journals In Vitro Evaluation of the Allogeneic Bone Matrix Effect on the Adipose Mesenchymal Stromal Cells Characteristics in Combined Tissue Engineering

2021 ◽  
Vol 27 (1) ◽  
pp. 53-65
Author(s):  
L. A. Cherdantseva ◽  
E. A. Anastasieva ◽  
D. Ya. Aleynik ◽  
M. N. Egorikhina ◽  
I. A. Kirilova
Keyword(s):  
Tissue Engineering ◽  
Mesenchymal Stromal Cells ◽  
Stromal Cells ◽  
Bone Matrix ◽  
Allogeneic Bone ◽  
Spongy Bone ◽  
Allogenic Bone ◽  
Native Bone ◽  
Deproteinized Bone

The aim of the study was to evaluate in vitro the effect of native and deproteinized compact and spongy allogenic bone matrices on the characteristics of adipose mesenchymal stromal cells (ASC) in combined tissue engineering.Material and Methods. 24 samples of native and deproteinized compact and spongy bone were examined, which were exposed to mechanical treatment, modeling, followed by sterilization of the samples by ionizing radiation and bacteriological control of sterilization. Some of the samples underwent deproteinization. The characterized cultures of human ASC were used as test cultures to assess the interaction with the bone samples. The Cytation-5 fluorescent imager and Hoechst 3334 fluorochromes (BD Pharmingen™) and calcein (Calcein AM, BD Pharmingen™) were used to characterize the degree of adhesion, migration, and viability of ASC on bone matrix samples. Matrix cytotoxicity was evaluated by MTT assay on days 1 and 7 of extraction.Results. The bone matrix samples are characterized by the absence of cytotoxicity (rank 1). ASC demonstrated good adhesion and migration on any surface of the bone matrix and preservation of cell viability during 7 days of observation. Nuclei sizes of the cells adhered to the deproteinized bone matrix of the spongy structure increased by 25–30% compared to other samples. The cells on deproteinized bone matrix had greater size (the size of the cells from nuclei 8.8 to 11.5 μm, the average size of cells nuclei from an 86.3 μm to 129,0 μm, the average perimeter of the cells nuclei from 30.7 μm to 40.7 μm) than in the native bone matrix samples.Conclusion. The results of the study of various allogeneic bone matrices demonstrate that deep purification of the bone matrix determines the absence of cytotoxicity and the most favorable conditions for the adhesion, migration, proliferation and viability of ASC. Also makes it possible to use tissue engineering based on bone matrices of different structures. Deproteinized spongy bone matrices are best suited for this purpose.

scholarly journals Heterotopic osteogenesis induced by implantation of allogenic bone matrix graft into mouse muscle perimysium. A morphometric study

2010 ◽  
Vol 7 (1) ◽  
Author(s):  
Renato Faria Yassutaka Yaedú ◽  
Fernanda Lourenção Brighentti ◽  
Tania Mary Cestari ◽  
José Mauro Granjeiro ◽  
Rumio Taga
Keyword(s):  
Bone Matrix ◽  
Morphometric Study ◽  
Mouse Muscle ◽  
Allogenic Bone

Novel methods for demonstrating osseointegration of hydroxylapatite-coated titanium hip prostheses

1991 ◽  
Vol 49 ◽  
pp. 34-35 ◽  
Author(s):  
P. Frayssinet ◽  
J. Hanker ◽  
D. Hardy ◽  
B. Giammara
Keyword(s):  
Hip Prosthesis ◽  
Ethanol Concentration ◽  
Bone Matrix ◽  
Electron Microscopic Examination ◽  
Electron Microscopic ◽  
Hip Prostheses ◽  
Cellular Inclusions ◽  
Microscopic Studies ◽  
Diamond Saw ◽  
Plasma Sprayed

Prostheses implanted in hard tissues cannot be processed for electron microscopic examination or microanalysis in the same way as those in other tissues. For these reasons, we have developed methods allowing light and electron microscopic studies as well as microanalysis of the interface between bone and a metal biomaterial coated by plasma-sprayed hydroxylapatite(HA) ceramic.An HA-coated titanium hip prosthesis (Corail, Landos, France), which had been implanted for two years, was removed after death (unrelated to the orthopaedic problem). After fixation it was dehydrated in solutions of increasing ethanol concentration prior to embedment in polymethylmethacrylate(PMMA). Transverse femur sections were obtained with a diamond saw and the sections then carefully ground to a thickness of 200 microns. Plastic-embedded sections were stained for calcium with a silver methenamine modification of the von Kossa method for calcium staining and coated by carbon. They have been examined by back-scatter SEM on an ISI-SS60 operated at 25 KV. EDAX has been done on cellular inclusions and extracellular bone matrix.

Collagen XV as a bone matrix organizer

2013 ◽  
Author(s):  
David Vicente ◽  
Mikko Finnila ◽  
Valerio Izzi ◽  
Jarkko Koivunen ◽  
Taina Pihlajaniemi
Keyword(s):  
Bone Matrix ◽  
Collagen Xv
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