The Significance of Various Factors Associated with Hemorrhagic Transformation in Patients Treated with Recombinant Tissue Plasminogen Activator for Acute Stroke

Thrombolytic Therapy in Acute Ischemic Stroke II ◽

10.1007/978-3-642-78061-5_21 ◽

1993 ◽

pp. 145-152

Author(s):

M. S. Pessin ◽

S. M. Wolpert

Keyword(s):

Acute Stroke ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Recombinant Tissue Plasminogen Activator ◽

Hemorrhagic Transformation ◽

Factors Associated ◽

Tissue Plasminogen

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Can baseline magnetic resonance angiography (MRA) status become a foremost factor in selecting optimal acute stroke patients for recombinant tissue plasminogen activator (rt-PA) thrombolysis beyond 3 hours?

Neurological Research ◽

10.1179/174313209x444044 ◽

2009 ◽

Vol 31 (4) ◽

pp. 355-361 ◽

Author(s):

Li Ma ◽

Pei-Yi Gao ◽

Yan Lin ◽

Jing Xue ◽

Xiao-Chun Wang ◽

...

Keyword(s):

Magnetic Resonance ◽

Magnetic Resonance Angiography ◽

Acute Stroke ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Recombinant Tissue Plasminogen Activator ◽

Stroke Patients ◽

Tissue Plasminogen

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Rapid Breakdown of Microvascular Barriers and Subsequent Hemorrhagic Transformation After Delayed Recombinant Tissue Plasminogen Activator Treatment in a Rat Embolic Stroke Model

Stroke ◽

10.1161/01.str.0000023534.37670.f7 ◽

2002 ◽

Vol 33 (8) ◽

pp. 2100-2104 ◽

Author(s):

Rick M. Dijkhuizen ◽

Minoru Asahi ◽

Ona Wu ◽

Bruce R. Rosen ◽

Eng H. Lo

Keyword(s):

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Recombinant Tissue Plasminogen Activator ◽

Hemorrhagic Transformation ◽

Embolic Stroke ◽

Stroke Model ◽

Tissue Plasminogen

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Intracerebral Hemorrhage and Infarction Volume Following Recombinant Tissue Plasminogen Activator in an Acute Stroke Model

Thrombolytic Therapy in Acute Ischemic Stroke ◽

10.1007/978-3-642-76439-4_37 ◽

1991 ◽

pp. 259-261

Author(s):

G. J. del Zoppo ◽

K. E. Anderchek ◽

J. A. Koziol ◽

B. R. Copeland ◽

W. Hacke

Keyword(s):

Intracerebral Hemorrhage ◽

Acute Stroke ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Recombinant Tissue Plasminogen Activator ◽

Stroke Model ◽

Infarction Volume ◽

Tissue Plasminogen

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Intravenous Recombinant Tissue Plasminogen Activator in Acute Stroke

Thrombolytic Therapy in Acute Ischemic Stroke ◽

10.1007/978-3-642-76439-4_19 ◽

1991 ◽

pp. 161-167 ◽

Author(s):

R. von Kummer ◽

M. Forsting ◽

K. Sartor ◽

W. Hacke

Keyword(s):

Acute Stroke ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Recombinant Tissue Plasminogen Activator ◽

Tissue Plasminogen

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The Relevance of CT Scanning and Angiography for Patients with Acute Stroke Treated with Recombinant Tissue Plasminogen Activator

Thrombolytic Therapy in Acute Ischemic Stroke II ◽

10.1007/978-3-642-78061-5_26 ◽

1993 ◽

pp. 189-191

Author(s):

S. M. Wolpert ◽

M. S. Pessin

Keyword(s):

Acute Stroke ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Ct Scanning ◽

Recombinant Tissue Plasminogen Activator ◽

Tissue Plasminogen

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Controversies in cerebrovascular disease: high or low doses of recombinant tissue plasminogen activator to treat acute stroke? A literature review

Neurología (English Edition) ◽

10.1016/j.nrleng.2018.04.002 ◽

2020 ◽

Author(s):

V. Montalván Ayala ◽

Z. Rojas Cheje ◽

R. Aldave Salazar

Keyword(s):

Literature Review ◽

Cerebrovascular Disease ◽

Acute Stroke ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Recombinant Tissue Plasminogen Activator ◽

Low Doses ◽

Tissue Plasminogen

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Negative Fluid-Attenuated Inversion Recovery- Based Intravenous Thrombolysis Using Recombinant Tissue Plasminogen Activator in Acute Stroke Patients with Unknown Onset Time

Cerebrovascular Diseases Extra ◽

10.1159/000348552 ◽

2013 ◽

Vol 3 (1) ◽

pp. 35-45 ◽

Author(s):

Junya Aoki ◽

Kazumi Kimura ◽

Kensaku Shibazaki ◽

Yuki Sakamoto

Keyword(s):

Acute Stroke ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Intravenous Thrombolysis ◽

Recombinant Tissue Plasminogen Activator ◽

Inversion Recovery ◽

Stroke Patients ◽

Tissue Plasminogen ◽

Fluid Attenuated Inversion Recovery

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Evaluation of the recombinant tissue plasminogen activator pretreatment in acute stroke patients with large vessel occlusions treated with the direct bridging approach. Is it worth the effort?

European Journal of Neurology ◽

10.1111/ene.12569 ◽

2014 ◽

Vol 22 (2) ◽

pp. 322-327 ◽

Author(s):

L. Fjetland ◽

K. D. Kurz ◽

S. Roy ◽

M. W. Kurz

Keyword(s):

Acute Stroke ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Recombinant Tissue Plasminogen Activator ◽

Large Vessel ◽

Stroke Patients ◽

Tissue Plasminogen

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Response by Barreto and Grotta to Letter Regarding Article, “Randomized, Multicenter Trial of ARTSS-2 (Argatroban With Recombinant Tissue Plasminogen Activator for Acute Stroke)”

Stroke ◽

10.1161/strokeaha.117.018294 ◽

2017 ◽

Vol 48 (9) ◽

Author(s):

Andrew D. Barreto ◽

James C. Grotta

Keyword(s):

Acute Stroke ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Recombinant Tissue Plasminogen Activator ◽

Multicenter Trial ◽

Tissue Plasminogen

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Plasma kallikrein mediates brain hemorrhage and edema caused by tissue plasminogen activator therapy in mice after stroke

Blood ◽

10.1182/blood-2016-09-740670 ◽

2017 ◽

Vol 129 (16) ◽

pp. 2280-2290 ◽

Author(s):

Fabrício Simão ◽

Tuna Ustunkaya ◽

Allen C. Clermont ◽

Edward P. Feener

Keyword(s):

Acute Stroke ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Cerebral Edema ◽

Hemorrhagic Transformation ◽

Contact System ◽

Plasma Kallikrein ◽

Brain Hemorrhage ◽

Tissue Plasminogen

Key Points tPA activates the contact system, and PKal blockade enhances tPA-mediated thrombolysis. PKal contributes to hemorrhagic transformation and cerebral edema in mice with acute stroke receiving tPA.

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