Role of Langerhans Cells and Other Dendritic Cells in the Pathogenesis of Herpes Simplex Virus Type 1 Infection

1994 ◽  
pp. 262-280
Author(s):  
Eli Sprecher ◽  
Yechiel Becker
Keyword(s):  
Dendritic Cells ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Langerhans Cells ◽  
Simplex Virus

Role of herpes simplex virus type 1 (HSV-1) in the pathogenesis of peptic ulcer disease

2001 ◽  
Vol 120 (5) ◽  
pp. A136-A137
Author(s):  
K TSAMAKIDES ◽  
E PANOTOPOULOU ◽  
D DIMITROULOPOULOS ◽  
M CHRISTOPOULO ◽  
D XINOPOULOS ◽  
...  
Keyword(s):  
Peptic Ulcer ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Peptic Ulcer Disease ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Ulcer Disease ◽  
Simplex Virus

scholarly journals Role of the Carboxy Terminus of Herpes Simplex Virus Type 1 DNA Polymerase in its Interaction With UL42

1994 ◽  
Vol 75 (11) ◽  
pp. 3127-3135 ◽  
Author(s):  
H. S. Marsden ◽  
M. Murphy ◽  
G. L. McVey ◽  
K. A. MacEachran ◽  
A. M. Owsianka ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Dna Polymerase ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Carboxy Terminus ◽  
Simplex Virus

scholarly journals Combined cytotoxic activity of an infectious, but non-replicative herpes simplex virus type 1 and plasmacytoid dendritic cells against tumour cells

Immunology ◽  
2015 ◽  
Vol 146 (2) ◽  
pp. 327-338 ◽  
Author(s):  
Sabrina Thomann ◽  
Jan B. Boscheinen ◽  
Karin Vogel ◽  
David M. Knipe ◽  
Neal DeLuca ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Cytotoxic Activity ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Plasmacytoid Dendritic Cells ◽  
Tumour Cells ◽  
Simplex Virus

scholarly journals Early herpes simplex virus type 1 infection is dependent on regulated Rac1/Cdc42 signalling in epithelial MDCKII cells

2006 ◽  
Vol 87 (12) ◽  
pp. 3483-3494 ◽  
Author(s):  
Sven Hoppe ◽  
Mario Schelhaas ◽  
Verena Jaeger ◽  
Timo Liebig ◽  
Philipp Petermann ◽  
...  
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Dominant Negative ◽  
Actin Dynamics ◽  
Simplex Virus ◽  
Hsv 1

The aim of this study was to understand how molecular determinants of epithelial cells influence initial infection by herpes simplex virus type 1 (HSV-1). Upon infection of the epithelial MDCKII cell line, enhanced association of virus particles with cells forming actin protrusions was observed, suggesting a putative role of actin dynamics in HSV-1 infection. Thus, the impact of the small Rho-like GTPases Rac1, Cdc42 and RhoA acting as key regulators of actin dynamics was addressed. Endogenous Rac1 and Cdc42 were temporarily activated at 15 and 30 min after HSV-1 infection. When constitutively active Cdc42 or Rac1 mutants were expressed transiently, a significant decrease in infectivity was observed, whereas expression of RhoA mutants had no influence. Furthermore, dominant-negative Cdc42 led to decreased infectivity, whereas dominant-negative Rac1 had no effect. So far, the study of potential effectors indicated that Rac1/Cdc42 mutants inhibited infectivity independently of p21-activated kinase (Pak1). The inhibitory effect of Rac1/Cdc42 mutant expression on HSV-1 infection was characterized further and it was found that binding, internalization and transport of HSV-1 were not affected by expression of Rac1/Cdc42 mutants. Thus, these results provide the first evidence for a role of Rac1/Cdc42 signalling during early HSV-1 infection and suggest a mechanism relying on virus-induced regulation of Rac1/Cdc42 activities.

scholarly journals The role of natural killer cells in the development of herpes simplex virus type 1 induced stromal keratitis in mice

Eye ◽  
1994 ◽  
Vol 8 (3) ◽  
pp. 298-306 ◽  
Author(s):  
Richard R Tamesis ◽  
Elisabeth M Messmer ◽  
Beverly A Rice ◽  
James E Dutt ◽  
C Stephen Foster
Keyword(s):  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Natural Killer Cells ◽  
Natural Killer ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Stromal Keratitis ◽  
Simplex Virus

scholarly journals Both plasmacytoid dendritic cells and monocytes stimulate natural killer cells early during human herpes simplex virus type 1 infections

Immunology ◽  
2014 ◽  
Vol 143 (4) ◽  
pp. 588-600 ◽  
Author(s):  
Karin Vogel ◽  
Sabrina Thomann ◽  
Benjamin Vogel ◽  
Philipp Schuster ◽  
Barbara Schmidt
Keyword(s):  
Dendritic Cells ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Natural Killer Cells ◽  
Natural Killer ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Human Herpes ◽  
Simplex Virus

Role of herpes simplex virus type 1 (HSV-1) in the pathogenesis of peptic ulcer disease

2001 ◽  
Vol 120 (5) ◽  
pp. A136-A137
Author(s):  
Klisthenis X. Tsamakides ◽  
Evi Panotopoulou ◽  
Dimitrios A. Dimitroulopoulos ◽  
Maria Christopoulo ◽  
Dimitrios Xinopoulos ◽  
...  
Keyword(s):  
Peptic Ulcer ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Peptic Ulcer Disease ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Ulcer Disease ◽  
Simplex Virus
Sign in / Sign up

Export Citation Format

Share Document