Case Studies: Nerve Cuff Electrodes, Stimulation by Magnetic Fields

1990 ◽  
pp. 191-198
Author(s):  
Frank Rattay
Keyword(s):  
Magnetic Fields ◽  
Case Studies ◽  
Nerve Cuff ◽  
Cuff Electrodes ◽  
Nerve Cuff Electrodes

scholarly journals Selective stimulation of the ferret abdominal vagus nerve with multi-contact nerve cuff electrodes

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jonathan A. Shulgach ◽  
Dylan W. Beam ◽  
Ameya C. Nanivadekar ◽  
Derek M. Miller ◽  
Stephanie Fulton ◽  
...  
Keyword(s):  
Vagus Nerve ◽  
Nerve Fibers ◽  
The Body ◽  
Evoked Responses ◽  
Gi Tract ◽  
Selective Stimulation ◽  
Nerve Cuff ◽  
Cuff Electrodes ◽  
Nerve Cuff Electrodes ◽  
Stimulation Of

AbstractDysfunction and diseases of the gastrointestinal (GI) tract are a major driver of medical care. The vagus nerve innervates and controls multiple organs of the GI tract and vagus nerve stimulation (VNS) could provide a means for affecting GI function and treating disease. However, the vagus nerve also innervates many other organs throughout the body, and off-target effects of VNS could cause major side effects such as changes in blood pressure. In this study, we aimed to achieve selective stimulation of populations of vagal afferents using a multi-contact cuff electrode wrapped around the abdominal trunks of the vagus nerve. Four-contact nerve cuff electrodes were implanted around the dorsal (N = 3) or ventral (N = 3) abdominal vagus nerve in six ferrets, and the response to stimulation was measured via a 32-channel microelectrode array (MEA) inserted into the left or right nodose ganglion. Selectivity was characterized by the ability to evoke responses in MEA channels through one bipolar pair of cuff contacts but not through the other bipolar pair. We demonstrated that it was possible to selectively activate subpopulations of vagal neurons using abdominal VNS. Additionally, we quantified the conduction velocity of evoked responses to determine what types of nerve fibers (i.e., Aδ vs. C) responded to stimulation. We also quantified the spatial organization of evoked responses in the nodose MEA to determine if there is somatotopic organization of the neurons in that ganglion. Finally, we demonstrated in a separate set of three ferrets that stimulation of the abdominal vagus via a four-contact cuff could selectively alter gastric myoelectric activity, suggesting that abdominal VNS can potentially be used to control GI function.

Establishment of an in Vitro Model for Stress Testing of Vagal Nerve Cuff Electrodes

2013 ◽  
Author(s):  
Katja Prystaz ◽  
Christoph Ulmer ◽  
Karin H. Somerlik-Fuchs ◽  
Thilo B. Krueger
Keyword(s):  
Stress Testing ◽  
In Vitro Model ◽  
Vagal Nerve ◽  
Nerve Cuff ◽  
Cuff Electrodes ◽  
Nerve Cuff Electrodes ◽  
Vitro Model

scholarly journals Standing After Spinal Cord Injury With Four-Contact Nerve-Cuff Electrodes for Quadriceps Stimulation

2008 ◽  
Vol 16 (5) ◽  
pp. 473-478 ◽  
Author(s):  
L.E. Fisher ◽  
M.E. Miller ◽  
S.N. Bailey ◽  
J.A. Davis ◽  
J.S. Anderson ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Nerve Cuff ◽  
Cuff Electrodes ◽  
Cord Injury ◽  
Nerve Cuff Electrodes

scholarly journals “Long-term stability of stimulating spiral nerve cuff electrodes on human peripheral nerves”

2017 ◽  
Vol 14 (1) ◽  
Author(s):  
Breanne P. Christie ◽  
Max Freeberg ◽  
William D. Memberg ◽  
Gilles J. C. Pinault ◽  
Harry A. Hoyen ◽  
...  
Keyword(s):  
Peripheral Nerves ◽  
Term Stability ◽  
Long Term Stability ◽  
Nerve Cuff ◽  
Cuff Electrodes ◽  
Nerve Cuff Electrodes
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