Review of Histopathological Studies on OPLL of the Cervical Spine, with Insights into the Mechanism

OPLL ◽  
2007 ◽  
pp. 41-47 ◽  
Author(s):  
Nobuyuki Tsuzuki
2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Marshall T. Holland ◽  
Oliver E. Flouty ◽  
Liesl N. Close ◽  
Chandan G. Reddy ◽  
Matthew A. Howard

Extraskeletal Ewing’s sarcoma (EES) is a rare presentation, representing only 15% of all primary Ewing’s sarcoma cases. Even more uncommon is EES presenting as a primary focus in the spinal canal. These rapidly growing tumors often present with focal neurological symptoms of myelopathy or radiculopathy. There are no classic characteristic imaging findings and thus the physician must keep a high index of clinical suspicion. Diagnosis can only be definitively made by histopathological studies. In this report, we discuss a primary cervical spine EES in a 53-year-old man who presented with a two-month history of left upper extremity pain and acute onset of weakness. Imaging revealed a cervical spinal canal mass. After undergoing cervical decompression, histopathological examination confirmed a diagnosis of Ewing’s sarcoma. A literature search revealed fewer than 25 reported cases of primary cervical spine EES published in the past 15 years and only one report demonstrating this pathology in a patient older than 30 years of ageage=38. Given the low incidence of this pathology presenting in this age group and the lack of treatment guidelines, each patient’s plan should be considered on a case-by-case basis until further studies are performed to determine optimal evidence based treatment.


Neurosurgery ◽  
1988 ◽  
Vol 22 (2) ◽  
pp. 419-422 ◽  
Author(s):  
Curtis A. Dickman ◽  
Volker K.H. Sonntag ◽  
Peter Johnson ◽  
Marjorie Medina

Abstract This is the first published report of an amyloidoma localized to the cervical spine. Primary amyloidosis of bone is rare. Only 5 cases involving the spine have been described. We present a 74-year-old man with cervical and occipital radicular pain as the manifestations of an amyloidoma involving the 2nd cervical vertebra. The signs and symptoms of this disease, when localized to the vertebrae, are nonspecific and result from bony destruction and compression of neural structures. Diagnosis requires a high index of suspicion and, ultimately, adequate tissue biopsy for histopathological studies. Curative resection is possible for well-localized lesions. Additionally, external immobilization with a halo vest and bony grafting for fusion may be indicated when the cervical spine is involved. (Neurosurgery 22:419-422, 1988)


1998 ◽  
Vol 3 (1) ◽  
pp. 6-7
Author(s):  
Robert H. Haralson
Keyword(s):  

2004 ◽  
Vol 9 (5) ◽  
pp. 1-11
Author(s):  
Patrick R. Luers

Abstract The AMA Guides to the Evaluation of Permanent Impairment (AMA Guides), Fifth Edition, defines a motion segment as “two adjacent vertebrae, the intervertebral disk, the apophyseal or facet joints, and ligamentous structures between the vertebrae.” The range of motion from segment to segment varies, and loss of motion segment integrity is defined as “an anteroposterior motion of one vertebra over another that is greater than 3.5 mm in the cervical spine, greater than 2.5 mm in the thoracic spine, and greater than 4.5 mm in the lumbar spine.” Multiple etiologies are associated with increased motion in the cervical spine; some are physiologic or compensatory and others are pathologic. The standard radiographic evaluation of instability and ligamentous injury in the cervical spine consists of lateral flexion and extension x-ray views, but no single pattern of injury is identified in whiplash injuries. Fluoroscopy or cineradiographic techniques may be more sensitive than other methods for evaluating subtle abnormal motion in the cervical spine. The increased motion thus detected then must be evaluated to determine whether it represents normal physiologic motion, normal compensatory motion, motion related to underlying degenerative disk and/or facet disease, or increased motion related to ligamentous injury. Imaging studies should be performed and interpreted as instructed in the AMA Guides.


2005 ◽  
Vol 2 (2) ◽  
pp. 99-101 ◽  
Author(s):  
TVSP Murthy ◽  
Parmeet Bhatia ◽  
RL Gogna ◽  
T Prabhakar

2004 ◽  
Vol 1 (1) ◽  
pp. 43-47
Author(s):  
PK Sahoo ◽  
Prakash Singh ◽  
HS Bhatoe

1990 ◽  
Vol 9 (1) ◽  
pp. 13-29 ◽  
Author(s):  
Michael R. Marks ◽  
Gordon R. Reli ◽  
Francis R.S. Roumphrey

1990 ◽  
Vol 9 (2) ◽  
pp. 263-278 ◽  
Author(s):  
Michael R. Marks ◽  
Gordon R. Bell ◽  
Francis R.S. Boumphrey

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