Effects of Local Bending Load on Trabecular Bone Adaptation

Author(s):  
Yoshitaka Kameo ◽  
Ken-ichi Tsubota ◽  
Taiji Adachi
2014 ◽  
Vol 225 (10) ◽  
pp. 2833-2840 ◽  
Author(s):  
Yoshitaka Kameo ◽  
Taiji Adachi

Author(s):  
Ariane C. Scheuren ◽  
Paul Vallaster ◽  
Gisela A. Kuhn ◽  
Graeme R. Paul ◽  
Angad Malhotra ◽  
...  

1999 ◽  
Author(s):  
Mark J. Eichler ◽  
Chi Hyun Kim ◽  
X. Edward Guo

Abstract The role of mechanical loading in trabecular bone adaptation is important for the understanding of bone integrity in different loading scenarios such as microgravity and for the etiology of age-related bone fractures. There have been numerous in vivo animal studies of bone adaptation, most of which are related to cortical bone remodeling, aimed at the investigation of Wolff’s Law [4], An interesting experimental model for trabecular bone adaptation has been developed in the rat tail vertebrae [2,3]. This model is attractive for trabecular bone adaptation studies because a controlled mechanical load can be applied to a whole vertebra with minimal surgical trauma, using a relatively inexpensive animal model. In addition, with advanced micro computed tomography (micro-CT) or micro magnetic resonance imaging (micro-MRI) coupled with large scale finite element modeling techniques, it is possible to characterize the three-dimensional (3D) stress/strain environment in the bone tissue close to a cellular level (∼25μm) [1]. Therefore, this in vivo rat tail model has a tremendous potential for quantification of the relationship between mechanical stimulation and biological response in trabecular bone adaptation.


2020 ◽  
Vol 22 (3) ◽  
Author(s):  
Marco C. Marques ◽  
Jorge Belinha ◽  
António F. Oliveira ◽  
Maria Cristinha M. Cespedes ◽  
Renato M. Natal Jorge

Purpose: Bone is a hierarchical material that can be characterized from the microscale to macroscale. Multiscale models make it possible to study bone remodeling, inducing bone adaptation by using information of bone multiple scales. This work proposes a computationally efficient homogenization methodology useful for multiscale analysis. This technique is capable to define the homogenized microscale mechanical properties of the trabecular bone highly heterogeneous medium. Methods: In this work, a morphology - based fabric tensor and a set of anisotropic phenomenological laws for bone tissue was used, in order to define the bone micro-scale mechanical properties. To validate the developed methodology, several examples were performed in order to analyze its numerical behavior. Thus, trabecular bone and fabricated benchmarks patches (representing special cases of trabecular bone morphologies) were analyzed under compression. Results: The results show that the developed technique is robust and capable to provide a consistent material homogenization, indicating that the homogeneous models were capable to accurately reproduce the micro-scale patch mechanical behavior. Conclusions: The developed method has shown to be robust, computationally less demanding and enabling the authors to obtain close results when comparing the heterogeneous models with equivalent homogenized models. Therefore, it is capable to accurately predict the micro-scale patch mechanical behavior in a fraction of the time required by classic homogenization techniques.


Bone ◽  
2011 ◽  
Vol 48 (2) ◽  
pp. 399-405 ◽  
Author(s):  
Hoyan Lam ◽  
Minyi Hu ◽  
Yi-Xian Qin

Bone ◽  
2013 ◽  
Vol 52 (1) ◽  
pp. 372-379 ◽  
Author(s):  
Alyssa M. Weatherholt ◽  
Robyn K. Fuchs ◽  
Stuart J. Warden

2002 ◽  
Vol 35 (2) ◽  
pp. 247-256 ◽  
Author(s):  
Zev Miller ◽  
Moshe B. Fuchs ◽  
Mircea Arcan

2013 ◽  
Vol 64 (5) ◽  
pp. 366-379 ◽  
Author(s):  
Kristofer D. Sinclair ◽  
Ryan W. Farnsworth ◽  
Theresa X. Pham ◽  
Alex N. Knight ◽  
Roy D. Bloebaum ◽  
...  

2012 ◽  
Vol 45 ◽  
pp. S531
Author(s):  
Antonia Torcasio ◽  
Katharina Jähn ◽  
Maarten Van Guyse ◽  
Pieter Spaepen ◽  
Andrea E. Tami ◽  
...  

2014 ◽  
Vol 29 (4) ◽  
pp. 355-362 ◽  
Author(s):  
Alina Levchuk ◽  
Alexander Zwahlen ◽  
Claudia Weigt ◽  
Floor M. Lambers ◽  
Sandro D. Badilatti ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document