Modelling bone tissue engineering. Towards an understanding of the role of scaffold design parameters

Author(s):  
José A. Sanz-Herrera ◽  
Manuel Doblaré ◽  
José M. García-Aznar
2019 ◽  
Vol 10 (1) ◽  
pp. 16 ◽  
Author(s):  
Baboucarr Lowe ◽  
Mark P. Ottensmeyer ◽  
Chun Xu ◽  
Yan He ◽  
Qingsong Ye ◽  
...  

The conventional applicability of biomaterials in the field of bone tissue engineering takes into consideration several key parameters to achieve desired results for prospective translational use. Hence, several engineering strategies have been developed to model in the regenerative parameters of different forms of biomaterials, including bioactive glass and β-tricalcium phosphate. This review examines the different ways these two materials are transformed and assembled with other regenerative factors to improve their application for bone tissue engineering. We discuss the role of the engineering strategy used and the regenerative responses and mechanisms associated with them.


2014 ◽  
Vol 36 (4) ◽  
pp. 448-457 ◽  
Author(s):  
Marta R. Dias ◽  
José M. Guedes ◽  
Colleen L. Flanagan ◽  
Scott J. Hollister ◽  
Paulo R. Fernandes

2011 ◽  
Vol 17 (5) ◽  
pp. 331-347 ◽  
Author(s):  
Ana Rita Costa-Pinto ◽  
Rui L. Reis ◽  
Nuno M. Neves

2014 ◽  
Vol 9 (10) ◽  
pp. 1133-1149 ◽  
Author(s):  
Rainer Detsch ◽  
Aldo R. Boccaccini

RSC Advances ◽  
2013 ◽  
Vol 3 (28) ◽  
pp. 11073 ◽  
Author(s):  
Jaba Mitra ◽  
Garima Tripathi ◽  
Ashutosh Sharma ◽  
Bikramjit Basu

Polymers ◽  
2021 ◽  
Vol 13 (19) ◽  
pp. 3429
Author(s):  
Oscar Fraile-Martínez ◽  
Cielo García-Montero ◽  
Alejandro Coca ◽  
Miguel Angel Álvarez-Mon ◽  
Jorge Monserrat ◽  
...  

Polymer-based composites are a group of biomaterials that exert synergic and combined activity. There are multiple reported uses of these composites in multiple biomedical areas, such as drug carriers, in wound dressings, and, more prominently, in tissue engineering and regenerative medicine. Bone grafting is a promising field in the use of polymeric composites, as this is the second most frequently transplanted organ in the United States. Advances in novel biomaterials, such as polymeric composites, will undoubtedly be of great aid in bone tissue engineering and regeneration. In this paper, a general view of bone structure and polymeric composites will be given, discussing the potential role of these components in bone tissue. Moreover, the most relevant jawbone and maxillofacial applications of polymeric composites will be revised in this article, collecting the main knowledge about this topic and emphasizing the need of further clinical studies in humans.


Author(s):  
Zhan Jing ◽  
Zhihui Liang ◽  
Liang Yang ◽  
Wenyan Du ◽  
Tao Yu ◽  
...  

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