Random Peptide Library for Ligand and Drug Discovery

2016 ◽  
pp. 1-24 ◽  
Author(s):  
Tai Kubo
Keyword(s):  
Drug Discovery ◽  
Peptide Library ◽  
Random Peptide Library ◽  
Random Peptide

36. Random Peptide Library Based on a Spider Neurotoxin, and Utilization of the Library in in vitro Evolution Directed to GPCR Ligands

Toxicon ◽  
2012 ◽  
Vol 60 (2) ◽  
pp. 113 ◽  
Author(s):  
Tai Kubo ◽  
Seigo Ono ◽  
Tadashi Kimura ◽  
Suzuko Kobayashi ◽  
Tetsuro Kondo ◽  
...  
Keyword(s):  
Peptide Library ◽  
In Vitro Evolution ◽  
Random Peptide Library ◽  
Random Peptide

Definition of the peptide mimotope of cellular receptor for hepatitis C virus E2 protein using random peptide library

2001 ◽  
Vol 1 (1) ◽  
pp. 77
Author(s):  
In-Hee Lee ◽  
Jae-Eun Paik ◽  
Sang-Yong Seol ◽  
Dae-Hyun Seog ◽  
Sae-Gwang Park ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Peptide Library ◽  
Cellular Receptor ◽  
E2 Protein ◽  
Random Peptide Library ◽  
Random Peptide ◽  
Definition Of

Isolation of lung tumor specific peptides from a random peptide library: generation of diagnostic and cell-targeting reagents

2003 ◽  
Vol 202 (2) ◽  
pp. 219-230 ◽  
Author(s):  
Tsuksa Oyama ◽  
Kathryn F. Sykes ◽  
Kausar N. Samli ◽  
John D. Minna ◽  
Stephen Albert Johnston ◽  
...  
Keyword(s):  
Lung Tumor ◽  
Peptide Library ◽  
Cell Targeting ◽  
Random Peptide Library ◽  
Random Peptide

scholarly journals Identification of Peptides That Inhibit the DNA Binding, trans-Activator, and DNA Replication Functions of the Human Papillomavirus Type 11 E2 Protein

2004 ◽  
Vol 78 (5) ◽  
pp. 2637-2641 ◽  
Author(s):  
Su-Jun Deng ◽  
Kenneth H. Pearce ◽  
Eric P. Dixon ◽  
Kelly A. Hartley ◽  
Thomas B. Stanley ◽  
...  
Keyword(s):  
Cell Culture ◽  
Human Papillomavirus ◽  
Dna Replication ◽  
Transcriptional Activation ◽  
Synthetic Peptides ◽  
Dna Interaction ◽  
Peptide Library ◽  
Random Peptide Library ◽  
Random Peptide

ABSTRACT Peptide antagonists of the human papillomavirus type 11 (HPV-11) E2-DNA association were identified using a filamentous bacteriophage random peptide library. Synthetic peptides antagonized the E2-DNA interaction, effectively blocked E2-mediated transcriptional activation of a reporter gene in cell culture, and inhibited E1-E2-mediated HPV-11 DNA replication in vitro. These peptides may prove to be useful tools for characterizing E2 function and for exploring the effectiveness of E2-inhibitor-based treatments for HPV-associated diseases.

Mimotope of Leptospira from phage-displayed random peptide library is reactive with both monoclonal antibodies and patients’ sera

2006 ◽  
Vol 115 (1-3) ◽  
pp. 54-63 ◽  
Author(s):  
R TUNGTRAKANPOUNG ◽  
P PITAKSAJJAKUL ◽  
N NANGARM ◽  
W CHAICUMPA ◽  
P EKPO ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Peptide Library ◽  
Random Peptide Library ◽  
Random Peptide
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