The epidemiology of multidrug-resistant tuberculosis in the United States and other established market economies

2000 ◽  
pp. 17-28
Author(s):  
Marisa Moore ◽  
Eugene McCray ◽  
Ida M. Onorato
Keyword(s):  
United States ◽  
The United States ◽  
Multidrug Resistant ◽  
Market Economies ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis

scholarly journals Multidrug-resistant tuberculosis in the United States, 2011–2016: patient characteristics and risk factors

2020 ◽  
Vol 24 (1) ◽  
pp. 92-99 ◽  
Author(s):  
M. P. Chen ◽  
R. Miramontes ◽  
J. S. Kammerer
Keyword(s):  
United States ◽  
Risk Factors ◽  
Patient Characteristics ◽  
The United States ◽  
Multidrug Resistant ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
Recent Transmission ◽  
National Tuberculosis ◽  
Mdr Tb

OBJECTIVE: To determine risk factors for multidrug-resistant tuberculosis (MDR-TB) and describe MDR-TB according to three characteristics: previous TB disease, recent transmission of MDR-TB, and reactivation of latent MDR-TB infection.SETTING and DESIGN: We used 2011–2016 surveillance data from the US National Tuberculosis Surveillance System and National Tuberculosis Genotyping Service and used logistic regression models to estimate risk factors associated with MDR-TB.RESULTS: A total of 615/45 209 (1.4%) cases were confirmed as MDR-TB; 111/615 (18%) reported previous TB disease; 41/615 (6.7%) were attributed to recent MDR-TB transmission; and 449/615 (73%) to reactivation. Only 12/41 (29%) patients with TB attributed to recent transmission were known to be contacts of someone with MDR-TB. For non-US-born patients, the adjusted odds ratios of having MDR-TB were 32.6 (95%CI 14.6–72.6) among those who were known to be contacts of someone with MDR-TB and 6.5 (95%CI 5.1–8.3) among those who had had previous TB disease.CONCLUSION: The majority of MDR-TB cases in the United States were associated with previous TB disease or reactivation of latent MDR-TB infection; only a small proportion of MDR-TB cases were associated with recent transmission.

scholarly journals Introduction and evaluation of multidrug-resistant tuberculosis supplemental surveillance in the United States

2019 ◽  
Vol 15 ◽  
pp. 100090 ◽  
Author(s):  
Annie Belanger ◽  
Sapna Bamrah Morris ◽  
Richard Brostrom ◽  
David Yost ◽  
Neela Goswami ◽  
...  
Keyword(s):  
United States ◽  
The United States ◽  
Multidrug Resistant ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis

scholarly journals Tuberculosis in the AIDS era.

1995 ◽  
Vol 8 (2) ◽  
pp. 180-199 ◽  
Author(s):  
K A Sepkowitz ◽  
J Raffalli ◽  
L Riley ◽  
T E Kiehn ◽  
D Armstrong
Keyword(s):  
Public Health ◽  
United States ◽  
The United States ◽  
Multidrug Resistant ◽  
Laboratory Evaluation ◽  
Polymorphism Analysis ◽  
Mycobacterium Tuberculosis Infection ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
Hospital Infection Control

A resurgence of tuberculosis has occurred in recent years in the United States and abroad. Deteriorating public health services, increasing numbers of immigrants from countries of endemicity, and coinfection with the human immunodeficiency virus (HIV) have contributed to the rise in the number of cases diagnosed in the United States. Outbreaks of resistant tuberculosis, which responds poorly to therapy, have occurred in hospitals and other settings, affecting patients and health care workers. This review covers the pathogenesis, epidemiology, clinical presentation, laboratory diagnosis, and treatment of Mycobacterium tuberculosis infection and disease. In addition, public health and hospital infection control strategies are detailed. Newer approaches to epidemiologic investigation, including use of restriction fragment length polymorphism analysis, are discussed. Detailed consideration of the interaction between HIV infection and tuberculosis is given. We also review the latest techniques in laboratory evaluation, including the radiometric culture system, DNA probes, and PCR. Current recommendations for therapy of tuberculosis, including multidrug-resistant tuberculosis, are given. Finally, the special problem of prophylaxis of persons exposed to multidrug-resistant tuberculosis is considered.

scholarly journals Epidemiology of Pediatric Multidrug-Resistant Tuberculosis in the United States, 1993–2014

2017 ◽  
Vol 65 (9) ◽  
pp. 1437-1443 ◽  
Author(s):  
Sarah E Smith ◽  
Robert Pratt ◽  
Lisa Trieu ◽  
Pennan M Barry ◽  
Dzung T Thai ◽  
...  
Keyword(s):  
United States ◽  
The United States ◽  
Multidrug Resistant ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis

scholarly journals Characteristics and costs of multidrug-resistant tuberculosis in-patient care in the United States, 2005–2007

2016 ◽  
Vol 20 (4) ◽  
pp. 435-441 ◽  
Author(s):  
S. M. Marks ◽  
Y. Hirsch-Moverman ◽  
K. Salcedo ◽  
E. A. Graviss ◽  
P. Oh ◽  
...  
Keyword(s):  
United States ◽  
Patient Care ◽  
The United States ◽  
Multidrug Resistant ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis

scholarly journals Factors Associated With All-Cause Mortality Among Patients With Multidrug-Resistant Tuberculosis—United States, 1993–2013

2017 ◽  
Vol 65 (11) ◽  
pp. 1924-1926 ◽  
Author(s):  
Jorge L Salinas ◽  
Lori R Armstrong ◽  
Benjamin J Silk ◽  
Maryam B Haddad ◽  
J Peter Cegielski
Keyword(s):  
United States ◽  
Multidrug Resistant ◽  
Factors Associated ◽  
Resistant Tuberculosis ◽  
Multidrug Resistant Tuberculosis ◽  
All Cause Mortality
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