Calcium-Induced Molecular and Structural Signaling in Striated Muscle Contraction

2002 ◽  
pp. 199-245 ◽  
Author(s):  
Herbert C. Cheung
Keyword(s):  
Muscle Contraction ◽  
Striated Muscle

The Filament Lattice of Striated Muscle

1998 ◽  
Vol 78 (2) ◽  
pp. 359-391 ◽  
Author(s):  
BARRY M. MILLMAN
Keyword(s):  
Muscle Contraction ◽  
Structural Changes ◽  
Striated Muscle ◽  
Muscle Fibers ◽  
Lattice Stability ◽  
X Ray Diffraction ◽  
Thin Filaments ◽  
Intact Muscle ◽  
Radial Forces ◽  
Speed Of Shortening

Millman, Barry M. The Filament Lattice of Striated Muscle. Physiol. Rev. 78: 359–391, 1998. — The filament lattice of striated muscle is an overlapping hexagonal array of thick and thin filaments within which muscle contraction takes place. Its structure can be studied by electron microscopy or X-ray diffraction. With the latter technique, structural changes can be monitored during contraction and other physiological conditions. The lattice of intact muscle fibers can change size through osmotic swelling or shrinking or by changing the sarcomere length of the muscle. Similarly, muscle fibers that have been chemically or mechanically skinned can be compressed with bathing solutions containing very large inert polymeric molecules. The effects of lattice change on muscle contraction in vertebrate skeletal and cardiac muscle and in invertebrate striated muscle are reviewed. The force developed, the speed of shortening, and stiffness are compared with structural changes occurring within the lattice. Radial forces between the filaments in the lattice, which can include electrostatic, Van der Waals, entropic, structural, and cross bridge, are assessed for their contributions to lattice stability and to the contraction process.

Limulus Striated Muscle Provides an Unusual Model for Muscle Contraction

1984 ◽  
pp. 67-87 ◽  
Author(s):  
M. M. Dewey ◽  
P. Brink ◽  
D. E. Colflesh ◽  
B. Gaylinn ◽  
S.-F. Fan ◽  
...  
Keyword(s):  
Muscle Contraction ◽  
Striated Muscle

Effects of Cortisone on Striated Muscle Contraction

1952 ◽  
Vol 171 (2) ◽  
pp. 354-358
Author(s):  
E. C. Del Pozo ◽  
J. Negrete M. ◽  
J. Ibarra ◽  
M. Fernández L.
Keyword(s):  
Muscle Contraction ◽  
Striated Muscle

scholarly journals Poorly Understood Aspects of Striated Muscle Contraction

2015 ◽  
Vol 2015 ◽  
pp. 1-28 ◽  
Author(s):  
Alf Månsson ◽  
Dilson Rassier ◽  
Georgios Tsiavaliaris
Keyword(s):  
Muscle Contraction ◽  
Structural Changes ◽  
Striated Muscle ◽  
Three Dimensional ◽  
Skeletal Muscle Function ◽  
Tension Development ◽  
Atomic Structures ◽  
Molecular Events ◽  
Physiological Properties

Muscle contraction results from cyclic interactions between the contractile proteins myosin and actin, driven by the turnover of adenosine triphosphate (ATP). Despite intense studies, several molecular events in the contraction process are poorly understood, including the relationship between force-generation and phosphate-release in the ATP-turnover. Different aspects of the force-generating transition are reflected in the changes in tension development by muscle cells, myofibrils and single molecules upon changes in temperature, altered phosphate concentration, or length perturbations. It has been notoriously difficult to explain all these events within a given theoretical framework and to unequivocally correlate observed events with the atomic structures of the myosin motor. Other incompletely understood issues include the role of the two heads of myosin II and structural changes in the actin filaments as well as the importance of the three-dimensional order. We here review these issues in relation to controversies regarding basic physiological properties of striated muscle. We also briefly consider actomyosin mutation effects in cardiac and skeletal muscle function and the possibility to treat these defects by drugs.

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