Influence of long-term treatment with ketanserin on blood pressure, pulmonary artery pressure, and cardiac output in patients with heart failure

1990 ◽  
Vol 4 (1) ◽  
pp. 85-87 ◽  
Author(s):  
Stephan Brune ◽  
Thomas Schmidt ◽  
Ulrich Tebbe ◽  
Heinrich Kreuzer
Keyword(s):  
Heart Failure ◽  
Blood Pressure ◽  
Cardiac Output ◽  
Pulmonary Artery ◽  
Pulmonary Artery Pressure ◽  
Term Treatment ◽  
Artery Pressure ◽  
Long Term Treatment ◽  
Patients With Heart Failure

A Comparison of the Acute Haemodynamic Effects of Propranolol and Pindolol at Rest and during Supine Exercise in Man

1980 ◽  
Vol 59 (s6) ◽  
pp. 465s-468s ◽  
Author(s):  
T. L. Svendsen ◽  
J. E. Carlsen ◽  
O. Hartling ◽  
A. McNair ◽  
J. Trap-Jensen
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Cardiac Output ◽  
Pulmonary Artery ◽  
Pulmonary Artery Pressure ◽  
Response Curves ◽  
Receptor Blocking ◽  
Artery Pressure ◽  
Arterial Blood ◽  
Β Receptor

1. Dose-response curves for heart rate, cardiac output, arterial blood pressure and pulmonary artery pressure were obtained in 16 male patients after intravenous administration of three increasing doses of pindolol, propranolol or placebo. All patients had an uncomplicated acute myocardial infarction 6–8 months earlier. 2. The dose-response curves were obtained at rest and during repeated bouts of supine bicycle exercise. The cumulative dose amounted to 0.024 mg/kg body weight for pindolol and to 0.192 mg/kg body weight for propranolol. 3. At rest propranolol significantly reduced heart rate and cardiac output by 12% and 15% respectively. Arterial mean blood pressure was reduced by 9.2 mmHg. Mean pulmonary artery pressure increased significantly by 2 mmHg. Statistically significant changes in these variables were not seen after pindolol or placebo. 4. During exercise pindolol and propranolol both reduced cardiac output, heart rate and arterial blood pressure to the same extent. After propranolol mean pulmonary artery pressure was increased significantly by 3.6 mmHg. Pindolol and placebo did not change pulmonary artery pressure significantly. 5. The study suggests that pindolol may offer haemodynamic advantages over β-receptor-blocking agents without intrinsic sympathomimetic activity during low activity of the sympathetic nervous system, and may be preferable in situations where the β-receptor-blocking effect is required only during physical or psychic stress.

Safety and accuracy of a wireless pulmonary artery pressure monitoring system in patients with heart failure

2011 ◽  
Vol 161 (3) ◽  
pp. 558-566 ◽  
Author(s):  
William T. Abraham ◽  
Philip B. Adamson ◽  
Ayesha Hasan ◽  
Robert C. Bourge ◽  
Salpy V. Pamboukian ◽  
...  
Keyword(s):  
Heart Failure ◽  
Pulmonary Artery ◽  
Monitoring System ◽  
Pulmonary Artery Pressure ◽  
Pressure Monitoring ◽  
Artery Pressure ◽  
Patients With Heart Failure

scholarly journals A Simplified Ultrasound Comet Tail Grading Scoring to Assess Pulmonary Congestion in Patients with Heart Failure

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Hong Li ◽  
Yi-Dan Li ◽  
Wei-Wei Zhu ◽  
Ling-Yun Kong ◽  
Xiao-Guang Ye ◽  
...  
Keyword(s):  
Heart Failure ◽  
Pulmonary Artery ◽  
Pulmonary Artery Pressure ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Systolic Pulmonary Artery Pressure ◽  
Pulmonary Congestion ◽  
Functional Classification ◽  
Artery Pressure ◽  
Patients With Heart Failure

Ultrasound lung comets (ULCs) are a nonionizing bedside approach to assess extravascular lung water. We evaluated a protocol for grading ULC score to estimate pulmonary congestion in heart failure patients and investigated clinical and echocardiographic correlates of the ULC score. Ninety-three patients with congestive heart failure, admitted to the emergency department, underwent pulmonary ultrasound and echocardiography. A ULC score was obtained by summing the ULC scores of 7 zones of anterolateral chest scans. The results of ULC score were compared with echocardiographic results, the New York Heart Association (NYHA) functional classification, radiologic score, and N-terminal pro-b-type natriuretic peptide (NT-proBNP). Positive linear correlations were found between the 7-zone ULC score and the following: E/e′, systolic pulmonary artery pressure, severity of mitral regurgitation, left ventricular global longitudinal strain, NYHA functional classification, radiologic score, and NT-proBNP. However, there was no significant correlation between ULC score and left ventricular ejection fraction, left ventricle diameter, left ventricular volume, or left atrial volume. A multivariate analysis identified the E/e′, systolic pulmonary artery pressure, and radiologic score as the only independent variables associated with ULC score increase. The simplified 7-zone ULC score is a rapid and noninvasive method to assess lung congestion. Diastolic rather than systolic performance may be the most important determinant of the degree of lung congestion in patients with heart failure.

Significance and prognostic impact of v wave on pulmonary artery pressure in patients with heart failure: beyond the wedge pressure

2020 ◽  
Vol 35 (8) ◽  
pp. 1079-1086
Author(s):  
Hiroyuki Iwano ◽  
Shinobu Yokoyama ◽  
Kiwamu Kamiya ◽  
Toshiyuki Nagai ◽  
Shingo Tsujinaga ◽  
...  
Keyword(s):  
Heart Failure ◽  
Pulmonary Artery ◽  
Pulmonary Artery Pressure ◽  
Prognostic Impact ◽  
Artery Pressure ◽  
Patients With Heart Failure ◽  
V Wave ◽  
Wedge Pressure

Abstract 13432: Pulmonary Artery Pressure-Guided Therapy in Patients With Heart Failure Using the CardioMEMS Device and HF Readmissions: Analysis of the National Readmissions Database

Circulation ◽  
2021 ◽  
Vol 144 (Suppl_1) ◽  
Author(s):  
Ernesto A Ruiz ◽  
Aaqib Malik ◽  
Kampaktsis Polydoros ◽  
Alexandros Briasoulis
Keyword(s):  
Heart Failure ◽  
Pulmonary Artery ◽  
Pulmonary Artery Pressure ◽  
Cox Regression ◽  
Readmission Rates ◽  
Cox Regression Analysis ◽  
Artery Pressure ◽  
Patients With Heart Failure ◽  
Nationally Representative ◽  
Guided Therapy

Introduction: Pulmonary artery pressure (PAP)-guided therapy in patients with heart failure (HF) using the CardioMEMS device (CMM), an implantable PAP sensor, has shown to reduce hospitalizations in prior studies. Hypothesis: We sought to evaluate the clinical benefit of the CMM device in regard to readmission rates using the National Readmission Database (NRD). Methods: We queried the NRD to identify patients who underwent CMM implantation (CPT code 33289) between years 2014 to 2018 and studied their HF readmissions. We compared CMM patients and their readmissions with a matched cohort of patients with HF without CMM. Multivariate Cox regression analysis was performed to adjust for other predictors of readmissions. Results: Prior to matching we identified 3,965,188 weighted HF patients without CMM and 1528 patients with CMM. After propensity score matching for several patient and hospital related characteristics, the cohort consisted of 1528 patients with CMM and 1528 with HF without CMM. Before matching CMM patients were younger, more frequently males, with higher rates of prior myocardial infarction and chronic kidney disease. Readmission rates at 30-days were 17.6% vs. 21% for patients with vs. without CMM respectively and remained statistically significant after matching (17.5% vs. 22.7%, p=0.01). The rates of 90-day (29.1% vs 36.5%, p=0.002) and 180-day (40.1% vs. 46.6%, p=0.03) readmissions were lower in the CMM group (Figure). In multivariable regression models, CMM was associated with lower risk of readmissions (HR, 0.78, 95% CI 0.64-0.94, p=0.01). Conclusions: The CardioMEMS device was associated with reduced HF rehospitalization rates in a nationally representative cohort of HF patients

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