Block copolymers of L-lactide and poly(ethylene glycol) for biomedical applications

1994 ◽  
Vol 5 (6-7) ◽  
pp. 308-313 ◽  
Author(s):  
P. Cerral ◽  
M. Tricoli ◽  
L. Lelli ◽  
G. D. Guerra ◽  
R. Sbarbati Del Guerra ◽  
...  



2019 ◽  
Vol 6 (4) ◽  
pp. 107 ◽  
Author(s):  
Tomoki Maeda

Thermoresponsive hydrogels showing biocompatibility and degradability have been under intense investigation for biomedical applications, especially hydrogels composed of hydrophilic poly(ethylene glycol) (PEG) and hydrophobic poly(lactic acid-co-glycolic acid) (PLGA) as first-line materials. Even though various aspects such as gelation behavior, degradation behavior, drug-release behavior, and composition effect have been studied for 20 years since the first report of these hydrogels, there are still many outputs on parameters affecting their gelation, structure, and application. In this review, the current trends of research on linear block copolymers composed of PEG and PLGA during the last 5 years (2014–2019) are summarized. In detail, this review stresses newly found parameters affecting thermoresponsive gelation, findings from structural analysis by simulation, small-angle neutron scattering (SANS), etc., progress in biomedical applications including drug delivery systems and regeneration medicine, and nanocomposites composed of block copolymers with PEG and PLGA and nanomaterials (laponite).



2013 ◽  
Vol 23 (17) ◽  
pp. 5006-5010 ◽  
Author(s):  
Solène Passemard ◽  
Davide Staedler ◽  
Lucia Učňová ◽  
Guillaume Stéphane Schneiter ◽  
Phally Kong ◽  
...  


2017 ◽  
Vol 75 ◽  
pp. 918-925 ◽  
Author(s):  
Katarzyna Jelonek ◽  
Suming Li ◽  
Janusz Kasperczyk ◽  
Xiaohan Wu ◽  
Arkadiusz Orchel


2011 ◽  
Vol 22 (8) ◽  
pp. 1519-1525 ◽  
Author(s):  
Daniel K. Bonner ◽  
Cheuk Leung ◽  
Jane Chen-Liang ◽  
Loice Chingozha ◽  
Robert Langer ◽  
...  


2013 ◽  
Vol 27 (2) ◽  
pp. 216-226 ◽  
Author(s):  
Md. Kamal Khan ◽  
Mohammed Mizanur Rahman ◽  
Bodrun Nesa ◽  
Romana Nasrin ◽  
Swajal Molla ◽  
...  


2004 ◽  
Vol 97 (3) ◽  
pp. 567-574 ◽  
Author(s):  
Cheol-Hee Ahn ◽  
Su Young Chae ◽  
You Han Bae ◽  
Sung Wan Kim




Biomaterials ◽  
2004 ◽  
Vol 25 (2) ◽  
pp. 247-258 ◽  
Author(s):  
A.A. Deschamps ◽  
A.A. van Apeldoorn ◽  
H. Hayen ◽  
J.D. de Bruijn ◽  
U. Karst ◽  
...  


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