Prediction of reversible perfusion defects by quantitative analysis of post-exercise electrocardiogram-gated acquisition of technetium-99m 2-methoxyisobutylisonitrile myocardial perfusion scintigraphy

1992 ◽  
Vol 19 (9) ◽  
Author(s):  
Claudio Marcassa ◽  
Paolo Marzullo ◽  
Gianmario Sambuceti ◽  
Oberdan Parodi

Author(s):  
Nikant Sabharwal ◽  
Chee Yee Loong ◽  
Andrew Kelion

Planar acquisitions 122General approach to reporting SPECT images 124Review looped cine of raw data projections 126Qualitative and semi-quantitative evaluation of tomographic slices 128Quantitative analysis 132Gated SPECT 134Attenuation correction 136Image artefacts 138Instrumentation-related artefacts 140Processing-related and display-related artefacts ...



2015 ◽  
Vol 1084 ◽  
pp. 527-531
Author(s):  
Konstantin V. Zavadovsky ◽  
Marina O. Gulya ◽  
Yuriy B. Lishmanov ◽  
Vera V. Verkhoturova

In this study we used technetium-99m-labeled lipophilic complex of methoxy-isobutyl-isonitrile (99mTc-MIBI) and iopromide to assess coronary atherosclerosis in patients with coronary artery disease (CAD). The study included 33 patients with CAD who underwent myocardial perfusion scintigraphy with 99mTc-MIBI and computed tomography angiography (MDCTA) with iopromide. Patients who have comparable with the population-wide level risk of coronary events are characterized by the presence of borderline and significant stenosis 83% and 86%, respectively. 99mTc-MIBI and iopromide can be used to assess the severity of coronary atherosclerosis in patients with CAD.





2005 ◽  
Vol 26 (2) ◽  
pp. 109-114 ◽  
Author(s):  
Ay??e Akta?? ◽  
H??lya Yalcin ◽  
Aynur Koyuncu ◽  
Alp Aydinalp ◽  
Haldun M??derrisoglu


Author(s):  
Joachim Bautz ◽  
Jörg Stypmann ◽  
Stefanie Reiermann ◽  
Hermann-Joseph Pavenstädt ◽  
Barbara Suwelack ◽  
...  

Abstract Background We aimed to compare the prognostic value of myocardial perfusion scintigraphy (MPS) and dobutamine stress echocardiography (DSE) in patients with end-stage renal disease (ESRD) without known coronary artery disease. Methods Two-hundred twenty-nine ESRD patients who applied for kidney transplantation at our centre were prospectively evaluated by MPS and DSE. The primary endpoint was a composite of myocardial infarction (MI) or all-cause mortality. The secondary endpoint included MI or coronary revascularization (CR) not triggered by MPS or DSE at baseline. Results MPS detected reversible ischemia in 31 patients (13.5%) and fixed perfusion defects in 13 (5.7%) patients. DSE discovered stress-induced wall motion abnormalities (WMAs) in 28 (12.2%) and at rest in 18 (7.9%) patients. MPS and DSE results agreed in 85.6% regarding reversible defects (κ = 0.358; P < .001) and in 90.8% regarding fixed defects (κ = 0.275; P < .001). Coronary angiography detected relevant stenosis > 50% in only 15 of 38 patients (39.5%) with pathological findings in MPS and/or DSE. At a median follow-up of 8 years and 10 months, the primary endpoint occurred in 70 patients (30.6%) and the secondary endpoint in 24 patients (10.5%). The adjusted Cox hazard ratios (HRs) for the primary endpoint were 1.77 (95% CI 1.02-3.08; P = .043) for perfusion defects in MPS and 1.36 (95% CI 0.78-2.37; P = ns) for WMA in DSE. The secondary endpoint was significantly correlated with the findings of both modalities, MPS (HR 3.21; 95% CI 1.35-7.61; P = .008) and DSE (HR 2.67; 95% CI 1.15-6.20; P = .022). Conclusion Perfusion defects in MPS are a stronger determinant of all-cause mortality, MI and the need for future CR compared with WMAs in DSE. Given the complementary functional information provided by MPS vs DSE, results are sometimes contradictory, which may indicate differences in the underlying pathophysiology.



Sign in / Sign up

Export Citation Format

Share Document