Recombination in the class III region of the mouse major histocompatibility complex

1994 ◽  
Vol 40 (4) ◽  
Author(s):  
Masayasu Yoshino ◽  
Tomoko Sagai ◽  
KirstenFischer Lindahl ◽  
Yutaka Toyoda ◽  
Yasuaki Shirayoshi ◽  
...  
Keyword(s):  
Major Histocompatibility Complex ◽  
Major Histocompatibility ◽  
Class Iii ◽  
Mouse Major Histocompatibility Complex ◽  
Histocompatibility Complex

scholarly journals Dissection of class III major histocompatibility complex haplotypes associated with rheumatoid arthritis

2004 ◽  
Vol 50 (7) ◽  
pp. 2122-2129 ◽  
Author(s):  
Julia L. Newton ◽  
Sin�ad M. J. Harney ◽  
Andrew E. Timms ◽  
Anne-Marie Sims ◽  
Kirk Rockett ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Major Histocompatibility Complex ◽  
Major Histocompatibility ◽  
Class Iii ◽  
Histocompatibility Complex

The mouse major histocompatibility complex: some assembly required

1999 ◽  
Vol 167 (1) ◽  
pp. 211-221 ◽  
Author(s):  
Claire Amadou ◽  
Attila Kumánovics ◽  
Elsy P. Jones ◽  
Doris Lambracht-Washington ◽  
Masayasu Yoshino ◽  
...  
Keyword(s):  
Major Histocompatibility Complex ◽  
Major Histocompatibility ◽  
Mouse Major Histocompatibility Complex ◽  
Histocompatibility Complex

Tracts of high or low sequence divergence in the mouse major histocompatibility complex.

1984 ◽  
Vol 3 (12) ◽  
pp. 2995-3003 ◽  
Author(s):  
M. Steinmetz ◽  
M. Malissen ◽  
L. Hood ◽  
A. Orn ◽  
R.A. Maki ◽  
...  
Keyword(s):  
Major Histocompatibility Complex ◽  
Sequence Divergence ◽  
Major Histocompatibility ◽  
Mouse Major Histocompatibility Complex ◽  
Histocompatibility Complex

scholarly journals The G9a gene in the human major histocompatibility complex encodes a novel protein containing ankyrin-like repeats

1993 ◽  
Vol 290 (3) ◽  
pp. 811-818 ◽  
Author(s):  
C M Milner ◽  
R D Campbell
Keyword(s):  
Major Histocompatibility Complex ◽  
Amino Acid ◽  
Fusion Protein ◽  
Protein Interactions ◽  
Terminal Region ◽  
Major Histocompatibility ◽  
Class Iii ◽  
Intracellular Protein ◽  
Human Major Histocompatibility Complex ◽  
Histocompatibility Complex

The class III region of the human major histocompatibility complex spans approx. 1.1 Mbp on the short arm of chromosome 6 and is known to contain at least 36 genes. The complete nucleotide sequence of a 3.4 kb mRNA from one of these genes, G9a (or BAT8), has been determined from cDNA and genomic DNA clones. The single-copy G9a gene encodes a protein product of 1001 amino acids with a predicted molecular mass of 111,518 Da. The C-terminal region (residues 730-999) of the G9a protein has been expressed in Escherichia coli as a fusion protein with the 26 kDa glutathione S-transferase of Schistosoma japonicum (Sj26). The fusion protein has been used to raise antisera which, in Western-blot analysis, cross-react specifically with an intracellular protein of approx. 98 kDa. The function of the G9a protein is unknown. However, comparison of the derived amino acid sequence of G9a with the protein databases has revealed interesting similarities with a number of other proteins. The C-terminal region of G9a is 35% identical with a 149 amino acid segment of the Drosophila trithorax protein. In addition the G9a protein has been shown to contain six contiguous copies of a 33-amino acid repeat. This repeat, originally identified in the Notch protein of Drosophila and known as the cdc10/SW16 or ANK repeat, is also found in a number of other human proteins and may be involved in intracellular protein-protein interactions.

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