Localization of gastrin-releasing peptide (GRP)-like immunoreactivity in the lysosomal compartment of the trigeminal ganglion cells of the rat

1992 ◽  
Vol 97 (3) ◽  
pp. 277-281
Author(s):  
M. Watanabe ◽  
H. Kominami ◽  
N. Yanaihara ◽  
H. Kondo
Keyword(s):  
Trigeminal Ganglion ◽  
Ganglion Cells ◽  
Lysosomal Compartment ◽  
Gastrin Releasing Peptide

Capsaicin and nicotine both activate a subset of rat trigeminal ganglion neurons

1996 ◽  
Vol 270 (6) ◽  
pp. C1807-C1814 ◽  
Author(s):  
L. Liu ◽  
S. A. Simon
Keyword(s):  
Trigeminal Ganglion ◽  
Acetylcholine Receptors ◽  
Ganglion Cells ◽  
Whole Cell Patch Clamp ◽  
Current Voltage ◽  
Trigeminal Ganglion Neurons ◽  
Ganglion Neurons ◽  
Relationship Of ◽  
Current Voltage Relationship ◽  
Voltage Relationship

Nicotine and capsaicin produce many similar physiological responses that include pain, irritation, and vasodilation. To determine whether neuronal nicotine acetylcholine receptors (nAChR) are present on capsaicin-sensitive neurons, whole cell patch-clamp recordings were performed on rat trigeminal ganglion cells. It was found that approximately 20% of the total number of neurons tested was activated by both 100 microM nicotine and 1 nM capsaicin. Other subsets of neurons were activated by only one of these compounds, whereas a fourth subset was not activated by either compound. At -60 mV, the magnitude of the capsaicin-activated currents was about three times larger than the magnitude of the nicotine-activated currents. The current-voltage relationship of the nAChR exhibited marked rectification, such that for voltages > or = 0 mV the current was essentially zero. In contrast, the current-voltage relationship of the capsaicin-activated current was ohmic from +/- 60 mV. These data indicate the existence of subsets of capsaicin-sensitive afferent neurons.

scholarly journals PACAP induces axonal elongation in cultured monkey trigeminal ganglion cells

2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
Emi Nakajima ◽  
Ryan D. Walkup ◽  
Thomas R. Shearer ◽  
Mitsuyoshi Azuma
Keyword(s):  
Trigeminal Ganglion ◽  
Ganglion Cells ◽  
Axonal Elongation

scholarly journals Pattern of intracranial and extracranial projections of trigeminal ganglion cells

1986 ◽  
Vol 6 (8) ◽  
pp. 2200-2207 ◽  
Author(s):  
TP O'Connor ◽  
D van der Kooy
Keyword(s):  
Trigeminal Ganglion ◽  
Ganglion Cells

scholarly journals Immunohistochemical colocalization of TREK-1, TREK-2 and TRAAK with TRP channels in the trigeminal ganglion cells

2009 ◽  
Vol 454 (2) ◽  
pp. 129-133 ◽  
Author(s):  
Yoshio Yamamoto ◽  
Taku Hatakeyama ◽  
Kazuyuki Taniguchi
Keyword(s):  
Trigeminal Ganglion ◽  
Trp Channels ◽  
Ganglion Cells

Increase of Galanin in Trigeminal Ganglion during Tooth Movement

2006 ◽  
Vol 85 (7) ◽  
pp. 658-663 ◽  
Author(s):  
T. Deguchi ◽  
T. Yabuuchi ◽  
R. Ando ◽  
H. Ichikawa ◽  
T. Sugimoto ◽  
...  
Keyword(s):  
Trigeminal Ganglion ◽  
Periodontal Ligament ◽  
Tooth Movement ◽  
Ganglion Cells ◽  
Nerve Fibers ◽  
Size Spectrum ◽  
Pain Transmission ◽  
Trigeminal Ganglion Neurons ◽  
Ganglion Neurons ◽  
Experimental Tooth Movement

It is known that nerve fibers containing neuropeptides such as galanin increase in the periodontal ligament during experimental tooth movement. However, the origin of galanin-containing nerve fibers in the periodontal ligament remains unclear. This study was conducted to examine our hypothesis that the increased galanin nerve fibers have a sensory neuronal origin, and that the peptide is associated with pain transmission and/or periodontal ligament remodeling during experimental tooth movement. In control rats, galanin-immunoreactive trigeminal ganglion cells were very rare and were observed predominantly in small ganglion cells. After 3 days of experimental tooth movement, galanin-immunoreactive trigeminal ganglion cells significantly increased, and the most marked increase was observed at 5 days after experimental tooth movement. Furthermore, their cell size spectrum also significantly changed after 3 and 5 days of movement: Medium-sized and large trigeminal ganglion cells began expressing, and continued to express, galanin until 14 days after experimental tooth movement. These findings suggest that the increase of galanin in the periodontal ligament during experimental tooth movement at least partially originates from trigeminal ganglion neurons and may play a role in pain transmission and/or periodontal remodeling.

PACAP Induces Neurite Outgrowth in Cultured Trigeminal Ganglion Cells and Recovery of Corneal Sensitivity After Flap Surgery in Rabbits

2007 ◽  
Vol 143 (2) ◽  
pp. 255-262.e1 ◽  
Author(s):  
Chiho Fukiage ◽  
Takeshi Nakajima ◽  
Yoshiko Takayama ◽  
Yoko Minagawa ◽  
Thomas R. Shearer ◽  
...  
Keyword(s):  
Neurite Outgrowth ◽  
Trigeminal Ganglion ◽  
Ganglion Cells ◽  
Flap Surgery ◽  
Corneal Sensitivity
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