A human-human hybridoma secreting anti-Pseudomonas aeruginosa exotoxin-A monoclonal antibody with highly potent neutralizing activity

Masato Kuriyama; Yuzo Ichimori; Susumu Iwasa; Kyozo Tsukamoto

doi:10.1007/bf00365263

A human-human hybridoma secreting anti-Pseudomonas aeruginosa exotoxin-A monoclonal antibody with highly potent neutralizing activity

Cytotechnology ◽

10.1007/bf00365263 ◽

1990 ◽

Vol 3 (1) ◽

pp. 31-37 ◽

Cited By ~ 5

Author(s):

Masato Kuriyama ◽

Yuzo Ichimori ◽

Susumu Iwasa ◽

Kyozo Tsukamoto

Keyword(s):

Monoclonal Antibody ◽

Pseudomonas Aeruginosa ◽

Exotoxin A ◽

Neutralizing Activity ◽

Pseudomonas Aeruginosa Exotoxin

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Binding of monoclonal antibody specific for domain Ia/II of Pseudomonas aeruginosa exotoxin A at pH 4 strongly neutralizes exotoxin A-induced cytotoxicity in cell culture and in vivo.

Infection and Immunity ◽

10.1128/iai.60.3.1061-1068.1992 ◽

1992 ◽

Vol 60 (3) ◽

pp. 1061-1068 ◽

Cited By ~ 3

Author(s):

H Ohtsuka ◽

K Horigome ◽

A Higuchi ◽

N Nomura ◽

H Ochi ◽

...

Keyword(s):

Cell Culture ◽

Monoclonal Antibody ◽

Pseudomonas Aeruginosa ◽

Exotoxin A ◽

Pseudomonas Aeruginosa Exotoxin

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A hyman hybrid hybridoma producing a bispecific monoclonal antibody that can target tumor cells for attack by Pseudomonas aeruginosa exotoxin A

Cytotechnology ◽

10.1007/bf00148811 ◽

1990 ◽

Vol 4 (1) ◽

pp. 59-68 ◽

Cited By ~ 5

Author(s):

Susumu Honda ◽

Yuzo Ichimori ◽

Susumu Iwasa

Keyword(s):

Monoclonal Antibody ◽

Pseudomonas Aeruginosa ◽

Tumor Cells ◽

Exotoxin A ◽

Bispecific Monoclonal Antibody ◽

Pseudomonas Aeruginosa Exotoxin

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Characterization of monoclonal antibody B7, which neutralizes the cytotoxicity of Pseudomonas aeruginosa exotoxin A.

Clinical and Diagnostic Laboratory Immunology ◽

10.1128/cdli.3.6.727-732.1996 ◽

1996 ◽

Vol 3 (6) ◽

pp. 727-732 ◽

Cited By ~ 3

Author(s):

H F Shang ◽

M L Yeh ◽

C P Lin ◽

J Hwang

Keyword(s):

Monoclonal Antibody ◽

Pseudomonas Aeruginosa ◽

Exotoxin A ◽

Pseudomonas Aeruginosa Exotoxin

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Faculty Opinions recommendation of Host translational inhibition by Pseudomonas aeruginosa Exotoxin A Triggers an immune response in Caenorhabditis elegans.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717949453.793454656 ◽

2012 ◽

Author(s):

Dominique Ferrandon

Keyword(s):

Immune Response ◽

Pseudomonas Aeruginosa ◽

Caenorhabditis Elegans ◽

Exotoxin A ◽

Translational Inhibition ◽

Pseudomonas Aeruginosa Exotoxin

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Active site of Pseudomonas aeruginosa exotoxin A. Glutamic acid 553 is photolabeled by NAD and shows functional homology with glutamic acid 148 of diphtheria toxin.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)47472-8 ◽

1987 ◽

Vol 262 (18) ◽

pp. 8707-8711 ◽

Cited By ~ 13

Author(s):

S F Carroll ◽

R J Collier

Keyword(s):

Pseudomonas Aeruginosa ◽

Glutamic Acid ◽

Active Site ◽

Diphtheria Toxin ◽

Exotoxin A ◽

Functional Homology ◽

Pseudomonas Aeruginosa Exotoxin

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Restoration of enzymic activity and cytotoxicity of mutant, E553C, Pseudomonas aeruginosa exotoxin A by reaction with iodoacetic acid.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)68762-9 ◽

1988 ◽

Vol 263 (13) ◽

pp. 6146-6149 ◽

Cited By ~ 2

Author(s):

M Lukac ◽

R J Collier

Keyword(s):

Pseudomonas Aeruginosa ◽

Iodoacetic Acid ◽

Enzymic Activity ◽

Exotoxin A ◽

Pseudomonas Aeruginosa Exotoxin

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Isolation and characterization of Pseudomonas aeruginosa exotoxin A binding glycoprotein from mouse LM cells

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)52256-0 ◽

1991 ◽

Vol 266 (4) ◽

pp. 2390-2396 ◽

Cited By ~ 3

Author(s):

M R Thompson ◽

J Forristal ◽

P Kauffmann ◽

T Madden ◽

K Kozak ◽

...

Keyword(s):

Pseudomonas Aeruginosa ◽

Exotoxin A ◽

Isolation And Characterization ◽

Pseudomonas Aeruginosa Exotoxin ◽

Binding Glycoprotein

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EGF ligand fused to truncated Pseudomonas�aeruginosa exotoxin�A specifically targets and inhibits EGFR‑positive cancer cells

Oncology Reports ◽

10.3892/or.2018.6685 ◽

2018 ◽

Cited By ~ 1

Author(s):

Saeed Hashimi ◽

Brock Grant ◽

Naif Alqurashi ◽

Faisal Alowaidi ◽

Ming Wei

Keyword(s):

Pseudomonas Aeruginosa ◽

Cancer Cells ◽

Exotoxin A ◽

Pseudomonas Aeruginosa Exotoxin

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Construction, expression, and activity of a novel immunotoxin comprising a humanized antiepidermal growth factor receptor scFv and modified Pseudomonas aeruginosa exotoxin A

Anti-Cancer Drugs ◽

10.1097/cad.0000000000000452 ◽

2017 ◽

Vol 28 (3) ◽

pp. 263-270 ◽

Cited By ~ 1

Author(s):

Bahman Akbari ◽

Safar Farajnia ◽

Nosratollah Zarghami ◽

Nejat Mahdieh ◽

Mohammad Rahmati ◽

...

Keyword(s):

Pseudomonas Aeruginosa ◽

Growth Factor ◽

Growth Factor Receptor ◽

Exotoxin A ◽

Pseudomonas Aeruginosa Exotoxin ◽

Expression And Activity

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Host-pathogen interactions: The role of Pseudomonas aeruginosa exotoxin A in modulation of Galleria mellonella immune response

Journal of Invertebrate Pathology ◽

10.1016/j.jip.2021.107706 ◽

2021 ◽

pp. 107706

Author(s):

Bartłomiej Iwański ◽

Mariola Andrejko

Keyword(s):

Immune Response ◽

Pseudomonas Aeruginosa ◽

Galleria Mellonella ◽

Exotoxin A ◽

Host Pathogen Interactions ◽

Host Pathogen ◽

Pseudomonas Aeruginosa Exotoxin

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