Effects of monoamine oxidase inhibitors on the copulatory behavior of male rats

1972 ◽  
Vol 24 (2) ◽  
pp. 209-217 ◽  
Author(s):  
Donald A. Dewsbury ◽  
Harry N. Davis ◽  
Paul E. Jansen
1966 ◽  
Vol 35 (3) ◽  
pp. 217-222 ◽  
Author(s):  
U. ZOR ◽  
H. AILABOUNI ◽  
F. G. SULMAN

SUMMARY The mechanism by which combined treatment with monoamine oxidase inhibitors and a corticosteroid reduces the weight of the accessory sex glands in intact rats by about one half has been studied. Phenelzine sulphate in combination with hydrocortisone acetate given for 30 days to ovariectomized rats reduced the pituitary stores of luteinizing hormone (LH) by 33%. Similar reductions in somatotrophic hormone, corticotrophin and thyroid-stimulating hormone content were found after comparable treatment, whereas luteotrophic hormone increased. The increase of weight of the seminal vesicles and prostate gland produced by human chorionic gonadotrophin could be partly antagonized by the simultaneous administration of mebanazine and dexamethasone, but the action of testosterone on these glands in castrated animals was not inhibited. Interference with the production and effectiveness of LH is therefore the most likely mode of action by which these drugs effect the reduction of the weight of the accessory sex glands.


2013 ◽  
Vol 12 (20) ◽  
pp. 2131-2144
Author(s):  
Dolores Vina ◽  
Silvia Serra ◽  
Manuel Lamela ◽  
Giovanna Delogu

2012 ◽  
Vol 9 (10) ◽  
pp. 958-961
Author(s):  
Joana Reis ◽  
Catarina Oliveira ◽  
Nuno Milhazes ◽  
Dolores Vina ◽  
Fernanda Borges

2012 ◽  
Vol 9 (10) ◽  
pp. 958-961 ◽  
Author(s):  
Joana Reis ◽  
Catarina Oliveira ◽  
Nuno Milhazes ◽  
Dolores Vina ◽  
Fernanda Borges

2016 ◽  
Vol 12 (2) ◽  
pp. 115-122 ◽  
Author(s):  
Bijo Mathew ◽  
Githa E. Mathew ◽  
Jerad Suresh ◽  
Gülberk Ucar ◽  
Rani Sasidharan ◽  
...  

The Lancet ◽  
1963 ◽  
Vol 282 (7319) ◽  
pp. 1233-1234 ◽  
Author(s):  
H.C. Bethune ◽  
R.H. Burrell ◽  
R.H. Culpan

1992 ◽  
Vol &NA; (386) ◽  
pp. 9
Author(s):  
&NA;

Angiology ◽  
1960 ◽  
Vol 11 (1) ◽  
pp. 53-54 ◽  
Author(s):  
Morris Fishbein

1973 ◽  
Vol 2 (4) ◽  
pp. 237-239 ◽  
Author(s):  
Deirdre V. Lovecky ◽  
Donald A. Dewsbury

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