Oxygen uptake in saline-perfused rabbit heart is decreased to a similar extent during reductions in flow and in arterial oxygen concentration

1989 ◽  
Vol 414 (1) ◽  
pp. 82-88 ◽  
Author(s):  
J. H. G. M. van Beek ◽  
P. Bouma ◽  
N. Westerhof
Keyword(s):  
Oxygen Uptake ◽  
Oxygen Concentration ◽  
Rabbit Heart ◽  
Arterial Oxygen ◽  
Similar Extent ◽  
Perfused Rabbit Heart

High-resolution1H NMR imaging of regional ischemia in the isolated perfused rabbit heart at 4.7 T

1991 ◽  
Vol 21 (1) ◽  
pp. 144-150 ◽  
Author(s):  
John C. Chatham ◽  
Stacey Ackerman ◽  
Stephen J. Blackband
Keyword(s):  
Rabbit Heart ◽  
Nmr Imaging ◽  
Regional Ischemia ◽  
Perfused Rabbit Heart

Facilitation by ‘low sodium-urea’ medium of the washout of dopamine β-hydroxylase released by potassium ions from the perfused rabbit heart

Neuroscience ◽  
1980 ◽  
Vol 5 (2) ◽  
pp. 453-457 ◽  
Author(s):  
E. Muscholl ◽  
K. Racke ◽  
H. Ritzel
Keyword(s):  
Rabbit Heart ◽  
Potassium Ions ◽  
Low Sodium ◽  
Perfused Rabbit Heart

Oxygen pulse

2021 ◽  
pp. 51-55
Author(s):  
William J.M. Kinnear ◽  
James H. Hull
Keyword(s):  
Cardiac Output ◽  
Oxygen Uptake ◽  
Arterial Oxygen Saturation ◽  
Recovery Phase ◽  
Arterial Oxygen ◽  
Low Cardiac Output ◽  
Oxygen Pulse ◽  
A Value ◽  
Peripheral Arterial ◽  
Mixed Venous

This chapter outlines how dividing the volume of oxygen uptake (VO2) by the pulse rate gives an estimate of the stroke volume of the heart. The amount of oxygen taken up with each heartbeat is called the oxygen pulse (O2 pulse). It should increase steadily on exercise to a value above 10 ml/beat and may continue to rise during the recovery phase. A low O2 pulse can be an indicator of low cardiac output. If the maximum VO2 (VO2max) is normal, caution should be used in the interpretation of a low O2 pulse. Sometimes the O2 pulse is abnormal because of a fall in peripheral arterial oxygen saturation (SpO2) or mixed venous oxygen levels.

Stability of myocardial O2 consumption-pressure-volume area relation in red cell-perfused rabbit heart

1991 ◽  
Vol 261 (5) ◽  
pp. H1630-H1635
Author(s):  
H. Yaku ◽  
B. K. Slinker ◽  
E. S. Myhre ◽  
M. W. Watkins ◽  
M. M. Lewinter
Keyword(s):  
Diastolic Pressure ◽  
Mechanical Energy ◽  
Rabbit Heart ◽  
Cardiac Contraction ◽  
Red Cell ◽  
O2 Consumption ◽  
Perfused Rabbit Heart ◽  
Total Mechanical Energy ◽  
Heart Preparation ◽  
Myocardial O2 Consumption

We evaluated the mechanical and energetic stability of the isolated rabbit heart perfused with a suspension of bovine red cells in Krebs-Henseleit buffer in terms of the pressure-volume area (PVA) concept. PVA, the area surrounded by the end-systolic and end-diastolic pressure-volume (P-V) relations and the systolic P-V trajectory of the P-V diagram, represents the total mechanical energy generated by each cardiac contraction. Myocardial O2 consumption (VO2) per beat has been reported to be highly linearly correlated with PVA. We used the slope and VO2-axis intercept of the VO2-PVA relation as energetic parameters and the maximum P-V ratio (Emax) as a contractility index of the left ventricle (LV) and compared them every 30 min for 120 min. Emax, the slope, and VO2 intercept of the VO2-PVA relation did not change significantly over 120 min compared with their control values [7.3 +/- 2.9 mmHg.ml-1.100 g LV, (1.67 +/- 0.40) x 10(-5) ml O2.mmHg-1.ml-1, and (3.26 +/- 1.01) x 10(-2) ml O2.beat-1.100 g LV-1, respectively]. However, the goodness of the linear fit of the VO2-PVA relation decreased after 90 min (r = 0.94 control, 0.62 at 90 min, and 0.64 at 120 min). Therefore, we conclude that the isolated bovine red cell-perfused rabbit heart preparation is stable for mechanical and energetic studies for at least 60 min.

Metabolic interrelations of substrates, pH, and oxygen in perfused rabbit heart

1974 ◽  
Vol 226 (6) ◽  
pp. 1309-1314 ◽  
Author(s):  
AF Whereat ◽  
J Nelson
Keyword(s):  
Rabbit Heart ◽  
Perfused Rabbit Heart

scholarly journals Cardiac inotropic rebound effect after washout of acetylcholine is associated with electrophysiological heterogeneity in Langendorff-perfused rabbit heart

2014 ◽  
Vol 7 (3) ◽  
pp. 755-757
Author(s):  
HAIJIAN LUO ◽  
JUNQIANG SI ◽  
FENGJIE ZHANG ◽  
ZHENYU YANG ◽  
RUXING WANG
Keyword(s):  
Rebound Effect ◽  
Rabbit Heart ◽  
Perfused Rabbit Heart
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