The afferent pathway for carotid body chemoreceptor input to the hypothalamic supraoptic nucleus in the rat

1984 ◽  
Vol 400 (1) ◽  
pp. 80-87 ◽  
Author(s):  
M. C. Harris ◽  
A. V. Ferguson ◽  
D. Banks
Keyword(s):  
Carotid Body ◽  
Supraoptic Nucleus ◽  
Afferent Pathway ◽  
Hypothalamic Supraoptic Nucleus

EFFECTS OF CHEMORECEPTOR AND BARORECEPTOR STIMULATION ON THE DISCHARGE OF HYPOTHALAMIC SUPRAOPTIC NEURONES IN RATS

1979 ◽  
Vol 82 (1) ◽  
pp. 115-125 ◽  
Author(s):  
M. C. HARRIS
Keyword(s):  
Supraoptic Nucleus ◽  
Carotid Sinus ◽  
Carotid Bifurcation ◽  
Cardiovascular Reflexes ◽  
Nacl Solution ◽  
Baroreceptor Stimulation ◽  
Vasopressin Secretion ◽  
Carotid Body Chemoreceptors ◽  
Hypothalamic Supraoptic Nucleus ◽  
Slight Inhibition

SUMMARY Experiments have been performed to examine the effects of activating the carotid body chemoreceptors and the arterial baroreceptors on the discharge of neurones within the hypothalamic supraoptic nucleus of the rat. Chemoreceptors were activated by intracarotid injection of 0·9% NaCl solution equilibrated with 100% CO2. The baroreceptors of the carotid sinus and aortic arch were activated by raising the blood pressure with an intravenous injection of phenylephrine. Chemoreceptor stimulation activated and baroreceptor stimulation inhibited the discharge of all the phasically discharging neurones tested. Neither stimulus had any consistent effect on non-phasically discharging neurones, although slight inhibition occasionally occurred. Anaesthesia of the carotid bifurcation abolished the effects of cardiovascular stimulation on the supraoptic neurones. Responses resumed when the anaesthesia wore off. However, the anaesthesia also seemed to alter the phasic pattern of discharge. The results are discussed with reference to the influence of the cardiovascular receptors upon the neurones in the supraoptic nucleus, and with reference to possible roles for the cardiovascular reflexes in control of vasopressin secretion.

Oxytocin in the periaqueductal gray mainly comes form the hypothalamic supraoptic nucleus to participate in pain modulation

Peptides ◽  
2019 ◽  
Vol 121 ◽  
pp. 170153
Author(s):  
Wen-Quan Jiang ◽  
Le-Le Bao ◽  
Fang-Jie Sun ◽  
Xi-Lin Liu ◽  
Jun Yang
Keyword(s):  
Supraoptic Nucleus ◽  
Periaqueductal Gray ◽  
Pain Modulation ◽  
Hypothalamic Supraoptic Nucleus

Urocortin 1 administered into the hypothalamic supraoptic nucleus inhibits food intake in freely fed and food-deprived rats

Amino Acids ◽  
2012 ◽  
Vol 44 (3) ◽  
pp. 879-885 ◽  
Author(s):  
A. Fatima ◽  
S. Andrabi ◽  
G. Wolf ◽  
M. Engelmann ◽  
M. G. Spina
Keyword(s):  
Food Intake ◽  
Supraoptic Nucleus ◽  
Urocortin 1 ◽  
Hypothalamic Supraoptic Nucleus
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