In vitro characteristics of a myxopapillary ependymoma of the filum terminale maintained in tissue and organ culture systems

1974 ◽  
Vol 27 (3) ◽  
pp. 185-200 ◽  
Author(s):  
Donald G. Rawlinson ◽  
Lucien J. Rubinstein ◽  
Mary M. Herman
Keyword(s):  
Organ Culture ◽  
Myxopapillary Ependymoma ◽  
Filum Terminale ◽  
Culture Systems ◽  
Tissue And Organ Culture

In vitro characteristics of a sacrococcygeal chordoma maintained in tissue and organ culture systems

1976 ◽  
Vol 35 (1) ◽  
pp. 13-25 ◽  
Author(s):  
Bruce C. Horten ◽  
Stephen R. Montague
Keyword(s):  
Organ Culture ◽  
Culture Systems ◽  
Tissue And Organ Culture

The Culture in vitro of Urogenital Organs of Pleurodeles waltlii

Development ◽  
1962 ◽  
Vol 10 (4) ◽  
pp. 465-470
Author(s):  
Charles L. Foote ◽  
Florence M. Foote
Keyword(s):  
Organ Culture ◽  
Germ Cells ◽  
Culture Medium ◽  
Developmental Stages ◽  
Rana Catesbeiana ◽  
Sex Differentiation ◽  
Organ Cultures ◽  
Tissue And Organ Culture ◽  
Pleurodeles Waltlii

Earlier reports (Foote & Foote, 1958a, b, 1959) describe growth and maintenance in vitro of larval organs, particularly gonads, of Rana catesbeiana and Xenopus laevis. Immature germ cells of both testes and ovaries are well maintained in vitro, especially if the culture medium is supplemented with watersoluble sex-hormonal substances, although germ cells in process of maturation become necrotic. Recently some urogenital organs from the salamander, Pleurodeles waltlii, have been grown in vitro. Tissues and organs from this amphibian might prove to be more suitable for tissue and organ culture investigations than those of Anurans. Animals at three different ages were used in this study: recently hatched larvae, metamorphosing animals, and adults. To determine whether sex differentiation would occur in vitro, trunk portions of young larvae of Pleurodeles waltlii of developmental stages 37–38 (Gallien & Durocher, 1957) were placed in organ cultures.

In vitro ovarian tissue and organ culture a review

10.2741/a892 ◽  
2002 ◽  
Vol 7 (4) ◽  
pp. d1979-1989
Author(s):  
Patricia B Hoyer
Keyword(s):  
Organ Culture ◽  
Ovarian Tissue ◽  
Tissue And Organ Culture

Studies on experimental malignant nerve sheath tumors maintained in tissue and organ culture systems

1976 ◽  
Vol 35 (1) ◽  
pp. 27-45 ◽  
Author(s):  
Alexander M. Spence ◽  
Lucien J. Rubinstein ◽  
Frances K. Conley ◽  
Mary M. Herman
Keyword(s):  
Organ Culture ◽  
Culture Systems ◽  
Nerve Sheath Tumors ◽  
Nerve Sheath ◽  
Tissue And Organ Culture

scholarly journals The antiviral activity of the compound chalcone (4-ethoxy-2-hydroxy-4, 6-dimethoxy-chalcone) against rubella virus in vitro

2008 ◽  
Vol 5 (3) ◽  
pp. 391-394 ◽  
Author(s):  
Baghdad Science Journal
Keyword(s):  
Antiviral Activity ◽  
Organ Culture ◽  
Rubella Virus ◽  
Side Effect ◽  
Therapeutic Index ◽  
Maximum Tolerated Dose ◽  
Antiviral Compound ◽  
Tissue And Organ Culture ◽  
Margin Of Safety

The studies on the antiviral compound chalcone in vitro in both tissue and organ culture systems against rubella virus glass that this compound relatively non toxic to the cell culture and organ culture of the concentration of 8 ug/ml or less, chalcone have significantly antiviral activity against rubella virus in tissue culture and organ culture. We find that a concentration of 0.03ug/ml or more inhibit the IOOTCID50 of rubella virus. The therapeutic index (TI) used in this study to evaluate the drug, the (TI) which is the ratio of the dose of drug which is just toxic (Maximum tolerated dose) to the dose which is just effective (Minimum effective dose). If this index is one or less it not possible to use the drug under the conditions outlined without causing side effect, if the index is larger than the margin of safety is accordingly great, the TI of chalcone against rubella virus more than 70, therefore this compound if used in man have no side effect .

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