Effect of electrical stimulation of the dorsolateral funiculus on cardiac rhythm changes in acute myocardial ischemia

1985 ◽  
Vol 100 (6) ◽  
pp. 1625-1627
Author(s):  
Yu. I. Pivovarov ◽  
S. A. Lebedev ◽  
G. N. Kryzhanovskii
1990 ◽  
Vol 110 (5) ◽  
pp. 1465-1467
Author(s):  
Ya. D. Mamedov ◽  
Z. D. Ismailova ◽  
G. Sh. Garaev ◽  
Z. D. Ismailova

1977 ◽  
Vol 40 (4) ◽  
pp. 768-778 ◽  
Author(s):  
P. R. Lennard ◽  
P. S. Stein

1. Electrical stimulation applied within the dorsolateral funiculus of the spinal cord of an intact, unanesthetized turtle can elicit rhythmic limb movements similar to those observed during swimming. 2. A spontaneous display of hindlimb swimming movements is not observed in adult turtles whose spinal cord is transected at D2. Such swimming movements are observed in these "low-spinal" turtles in response to electrical stimulation applied within the dorsolateral funiculus caudad to the transection. 3. The repetition rate of these swimming movements can be altered by changing stimulus parameters, such as the frequency of electrical pulses. 4. The present results indicate that, in the turtle, a neural pattern generator contributing to the production of hindlimb movements during swimming is located mainly in structures caudad to the cervical enlargement of the spinal cord. These data support the hypothesis that a pattern generator for locomotion is largely resident within the spinal cord.


1993 ◽  
Vol 69 (5) ◽  
pp. 1607-1620 ◽  
Author(s):  
R. Mackel ◽  
E. Miyashita

1. It was the aim of this study to show that nucleus Z of the cat medulla acts as a relay between the spinal cord and the ventral lateral (VL) nucleus of the motor thalamus. For this purpose, extracellular recordings were made from neurons that were antidromically identified by stimulation in the rostral thalamus, particularly VL, and orthodromically activated by electrical stimulation of the spinal cord and/or natural stimulation of the hindlimb. The electrophysiological work was complemented by anatomic work. Here, wheat germ agglutinin-horseradish peroxidase (WGA-HRP) was injected into nucleus Z and the termination sites of bulbothalamic projections were anterogradely labeled. 2. A total of 120 neurons were antidromically identified as projecting to thalamus: 101 to VL and 19 outside VL. The recording sites in nucleus Z were marked by dye injection or by electrolytic lesion. They were confined to a small region (roughly 1 mm in diameter), 2.8-3.7 mm rostral to obex, 2.9-3.8 mm lateral from the midline, and from the surface of the medulla to a depth of 1 mm. The antidromic latencies ranged between 0.8 and 3.2 ms, with no difference in latencies associated with location of neurons in nucleus Z or thalamic projection sites. 3. Injection of WGA-HRP labeled fibers and axon terminals in the contralateral thalamus. Terminal labeling was densest in the lateral parts of the mid- and caudal region of the VL nucleus and, to a lesser extent, in the adjacent rostrodorsal part of the ventro-posterior lateral (VPL) nucleus. The sites of terminal labeling in VL corresponded with location of antidromic stimulation sites. 4. Orthodromic activation of nucleus Z neurons was tested in response to electrical stimulation of the ipsilateral dorsolateral funiculus (which includes the dorsal spinocerebellar tract) and/or the dorsal columns. All neurons responded to stimulation of the dorsolateral funiculus (45/45). The responsiveness of 44 neurons was tested to stimulation of the dorsal columns. Only 8 of 44 tested responded with a discharge. The orthodromic latencies of unitary discharges ranged from 1.1 to 4.4 ms to stimulation of the dorsolateral funiculus, and from 1.1 to 4.9 ms to stimulation of the dorsal columns. Most responses are likely to be monosynaptic. Differences in latencies were not associated with location of recording sites or thalamic projection sites of nucleus Z neurons. 5. The responsiveness of many neurons (n = 84) was tested to natural stimulation of the ipsilateral hindlimb (which provides the sensory input to nucleus Z).(ABSTRACT TRUNCATED AT 400 WORDS)


1989 ◽  
Vol 485 (2) ◽  
pp. 333-348 ◽  
Author(s):  
M.J. Guinan ◽  
J.M. Rothfeld ◽  
S. Pretel ◽  
E.S. Culhane ◽  
E. Carstens ◽  
...  

1969 ◽  
Author(s):  
H. B. Van Twyver ◽  
M. D. Fairchild ◽  
M. B. Sterman

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